Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Niloofar Ghadirian"'
Autor:
Arash Keshavarzi Arshadi, Julia Webb, Milad Salem, Emmanuel Cruz, Stacie Calad-Thomson, Niloofar Ghadirian, Jennifer Collins, Elena Diez-Cecilia, Brendan Kelly, Hani Goodarzi, Jiann Shiun Yuan
Publikováno v:
Frontiers in Artificial Intelligence, Vol 3 (2020)
SARS-COV-2 has roused the scientific community with a call to action to combat the growing pandemic. At the time of this writing, there are as yet no novel antiviral agents or approved vaccines available for deployment as a frontline defense. Underst
Externí odkaz:
https://doaj.org/article/dc313295629747798bfad07f2859c280
Autor:
Christopher J. Zerio, Jared Sivinski, E. M. Kithsiri Wijeratne, Ya-Ming Xu, Duc T. Ngo, Andrew J. Ambrose, Luis Villa-Celis, Niloofar Ghadirian, Michael W. Clarkson, Donna D. Zhang, Nancy C. Horton, A. A. Leslie Gunatilaka, Raimund Fromme, Eli Chapman
Publikováno v:
Journal of medicinal chemistry.
A pulldown using a biotinylated natural product of interest in the 17β-hydroxywithanolide (17-BHW) class, physachenolide C (PCC), identified the bromodomain and extra-terminal domain (BET) family of proteins (BRD2, BRD3, and BRD4), readers of acetyl
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36
Publikováno v:
J Virol
Two new structures of the N-terminal domain of the main replication protein, NS1, of human parvovirus B19 (B19V) are presented here. This domain (NS1-nuc) plays an important role in the “rolling hairpin” replication of the single-stranded B19V DN
Publikováno v:
Journal of Biological Chemistry. 298:101760
Enzyme filamentation is a widespread phenomenon that mediates enzyme regulation and function. For the filament-forming sequence-specific DNA endonuclease SgrAI, the process of filamentation both accelerates its DNA cleavage activity and expands its D
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Scientia Iranica.
An improved and efficient method for the synthesis of 1- & 5-substituted 1H-tetrazole derivatives has been described in the presence of nano-ordered MCM-41-SO3H as an effective heterogeneous catalyst. This metal-free protocol, [2+3] cycloaddition of
Autor:
Nancy C. Horton, Niloofar Ghadirian
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Desirae M. Heitman, Claudia Barahona, Juan A. Sanchez, Kassidy J. Tompkins, Nancy C. Horton, L. Emilia Basantes, Barbara I. Chukwu, Jonathan L. Sanchez, Niloofar Ghadirian, Chad K. Park
Publikováno v:
Journal of virology. 93(5)
Here, we investigate an unusual antiviral mechanism developed in the bacterium Streptomyces griseus. SgrAI is a type II restriction endonuclease that forms run-on oligomer filaments when activated and possesses both accelerated DNA cleavage activity