Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Nilima Shukla"'
Autor:
Yanping Liu, Jamie Y. Jeremy, Shaun L. Sandow, Nilima Shukla, David C. Ellinsworth, David D. Gutterman
Publikováno v:
Microcirculation. 23:15-32
Myocardial perfusion and coronary vascular resistance are regulated by signalling metabolites released from the local myocardium that act either directly on the vascular smooth muscle cells (VSMC) or indirectly via stimulation of the endothelium. A p
Publikováno v:
2018 3rd IEEE International Conference on Recent Trends in Electronics, Information & Communication Technology (RTEICT).
The bandwidth and gain improvement of microstrip array antenna using stacked layer of parasitic patches and air as an efficient substrate is proposed. An array of 2x2 microstrip patches is suspended on air. This increases the efficiency as well as ga
Publikováno v:
Cardiovascular Research. 102:9-16
Endothelium-dependent smooth muscle hyperpolarization (EDH) increasingly predominates over endothelium-derived nitric oxide (NO) as a participant in vasodilation as vessel size decreases. Its underlying nature is highly variable between vessel types,
Publikováno v:
Journal of Cellular Physiology. 227:1941-1950
The protective actions of prostacyclin (PGI(2) ) are mediated by cyclic AMP (cAMP) which is reduced by type 4 phosphodiesterases (PDE4) which hydrolyze cAMP. Superoxide (O2(-)) from NADPH oxidase (Nox) is associated with impaired PGI(2) bioactivity.
Publikováno v:
European Journal of Pharmacology. 658:187-192
Thromboxane A 2 (TXA 2 ) upregulates and activates NADPH oxidase (Nox) both of which are associated with cardiovascular disease. The aim of this study, therefore, was to investigate the relationship between thromboxane A 2 synthase (TXAS) status and
Publikováno v:
BJU International. 106:1794-1798
OBJECTIVES To explore the possible role of of 8-isoprostane F2α (8-IPF2α) in the aetiology of erectile dysfunction (ED), as the over-production of superoxide (O2-) derived from nicotinamide adenine dinucleotide phosphate (NADPH) oxidase results in
Publikováno v:
Diabetologia. 53:980-988
There is evidence that plasma homocysteine augments vein graft failure and that it augments both micro- and macro-angiopathy in patients with diabetes mellitus. It is therefore suggested that homocysteine may augment vein graft thickening, a major ca
Autor:
Gianni D Angelini, Nilima Shukla, Saima Muzaffar, Jamie Y. Jeremy, Anna Sparatore, P. Del Soldato
Publikováno v:
British Journal of Pharmacology. 155:984-994
Background and purpose: Superoxide (O2•−), derived from nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, is associated with acute respiratory distress syndrome (ARDS). NADPH oxidase activity and expression are blocked by nitric oxide
Autor:
Graciela B. Sala-Newby, Jamie Y. Jeremy, Mark Bond, Gianni D Angelini, Saima Muzaffar, Andrew C. Newby, Nilima Shukla
Publikováno v:
British Journal of Pharmacology. 155:847-856
Background and purpose: To determine whether there is an association between vascular NADPH oxidase (NOX), superoxide, the small GTPase Rac1 and PDE type 5 (PDE5) in human vascular smooth muscle cell (hVSMCs). Experimental approach: hVSMCs were incub
Autor:
Raj Persad, Gianni D Angelini, Nick S. Greaves, Matthew Hotston, Jonathon Bloor, Jamie Y. Jeremy, Nilima Shukla
Publikováno v:
Asian Journal of Andrology. 10:905-913
To study the effects of homocysteine and copper on type 5 phosphodiesterase (PDE5) expression in cavernosal vascular smooth muscle cells (CVSMCs) and to investigate superoxide (O(2)(.-)) derived from nicotinamide adenine dinucleotide phosphate oxidas