Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nilima A. Patwardhan"'
Publikováno v:
Endocrine pathology. 10(2)
Downregulation of apoptosis and high expression of bcl-2 play an important role in the development of follicular lymphoma. However, little is known about apoptosis in thyroid disease, particularly with respect to the development of papillary carcinom
Autor:
Nilima A. Patwardhan, R. K. Brynes, V. Nelson, Sherif Rezk, Ashraf Khan, Andrew H. Fischer, M. Thein
Publikováno v:
Endocrine Pathology. 15:329-338
The morphologic distinction of benign and malignant thyroid follicular lesions can sometimes be challenging, therefore an immunohistochemical marker to aid in this distinction would be useful. beta-Catenin is one such potential marker. It is part of
Publikováno v:
Endocrine Pathology. 14:249-255
Previous studies have established that calcitonin (CT) and the calcitonin generelated peptide (CGRP) are synthesized and stored in subsets of hyperplastic parathyroid cells that also contain chromogranin B (Schmid, KW, et al. Lab Invest 73:90, 1995).
Autor:
Ricardo V. Lloyd, Marjorie Safran, Ashraf Khan, Songtao Wang, Nilima A. Patwardhan, Igor B. Rosenwald, Michael J. Hutzler
Publikováno v:
Thyroid. 11:1101-1107
Cell growth and proliferation depend on protein synthesis that is regulated, in part, by two eukaryotic translation initiation factors, eIF-4E and eIF-2alpha. These factors are transiently increased as normal cells respond to growth factors and are c
Autor:
Michael J. Hutzler, Songtao Wang, Ashraf Khan, Nilima A. Patwardhan, Marjorie Safran, Ricardo V. Lloyd
Publikováno v:
Modern Pathology. 13:882-887
Cell cycle progression is facilitated by cyclin-dependent kinases that are activated by cyclins including cyclin D1 and inactivated by cyclin-dependent kinase inhibitors (CDKIs) such as p27. Our previous studies have demonstrated decreased p27 expres
Publikováno v:
Endocrine Pathology. 11:331-340
Cyclins are prime cell-cycle regulators central to the control of cell proliferation in eukaryotic cells. The formation of cyclin/cyclin-dependent kinases (CDK) complexes activates the kinases and initiates a cascade of events, which directs cells th
Publikováno v:
Endocrine Pathology. 9:117-123
Previous studies have established that thyroid follicular neoplasms of higher malignant potential show a high p53 and low bc1-2 expression. This however has not been well studied in Oncocytic (Hurthle cell) neoplasms, the management of which remains
Publikováno v:
Journal of Endocrinological Investigation. 19:714-718
We evaluated the benefits of bilateral deep cervical plexus block regional anesthesia in healthy and high risk patients undergoing thyroid and parathyroid surgery and assessed its effects on respiratory function. Twenty-one patients undergoing thyroi
Autor:
Nilima A. Patwardhan, Michael D. Wertheimer, David A. Phillips, Richard Swanson, John K. Zawacki
Publikováno v:
Surgery. 119:714-717
LOCALIZING THE SOURCE o f i n t e rmi t t en t acute b l e e d i n g o f the small bowel is a diagnost ic chal lenge. In contrast , the source for con t inuous acute small bowel b l eed ing is usually easily local ized with d i rec t visual inspec t
Publikováno v:
Surgical Clinics of North America. 75:449-464
Papillary cancer is the most common thyroid cancer occurring in all age groups and is usually an indolent tumor, and patients have an excellent prognosis. The majority of patients with papillary cancer do well. It is for the small number of patients