Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Nili Jin"'
Autor:
Jian Liu, Sung-Nam Cho, Bindu Akkanti, Nili Jin, Jianqiang Mao, Weiwen Long, Tenghui Chen, Yiqun Zhang, Ximing Tang, Ignacio I. Wistub, Chad J. Creighton, Farrah Kheradmand, Francesco J. DeMayo
Publikováno v:
Cell Reports, Vol 10, Iss 9, Pp 1599-1613 (2015)
Lung cancer remains the leading cause of cancer death. Genome sequencing of lung tumors from patients with squamous cell carcinoma has identified SMAD4 to be frequently mutated. Here, we use a mouse model to determine the molecular mechanisms by whic
Externí odkaz:
https://doaj.org/article/ae48df414dea413c8150a8ac7da7547d
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14171 (2010)
Fluid accumulation is critical for lung distension and normal development. The multi-subunit γ-amino butyric acid type A receptors (GABAA) mainly act by mediating chloride ion (Cl-) fluxes. Since fetal lung actively secretes Cl--rich fluid, we inves
Externí odkaz:
https://doaj.org/article/b7195c75f43f477fba765a1476b3ad27
Autor:
San-Pin Wu, Jennifer L. Gilbert, Nili Jin, Ignacio I. Wistuba, Sung Nam Cho, Francesco J. DeMayo, Seyed Javad Moghaddam, Jian Liu
Publikováno v:
Lung Cancer. 112:47-56
Objectives Lung cancer is the leading cause of cancer related deaths worldwide and mutation activating KRAS is one of the most frequent mutations found in lung adenocarcinoma. Identifying regulators of KRAS may aid in the development of therapies to
Autor:
Chad J. Creighton, Nili Jin, Jianqiang Mao, Sung Nam Cho, Jian Liu, Ignacio I. Wistub, Tenghui Chen, Ximing Tang, Bindu Akkanti, Weiwen Long, Yiqun Zhang, Farrah Kheradmand, Francesco J. DeMayo
Publikováno v:
Cell Reports, Vol 10, Iss 9, Pp 1599-1613 (2015)
Cell reports
Cell reports
SUMMARY Lung cancer remains the leading cause of cancer death. Genome sequencing of lung tumors from patients with squamous cell carcinoma has identified SMAD4 to be frequently mutated. Here, we use a mouse model to determine the molecular mechanisms
Autor:
Sung Nam Cho, Yvonne Smith, Francesco J. DeMayo, Nili Jin, Ignacio I. Wistuba, Christopher M. Evans, M. Gabriela Raso, Yanan Yang, Thomas Ludwig, Jae Wook Jeong, Jonathan M. Kurie, Rudolph Yen
Publikováno v:
Development. 136:3347-3356
Mitogen-inducible gene 6 [Mig-6; Errfi1 (ErbB receptor feedback inhibitor 1); RALT (receptor-associated late transducer); gene 33] is a ubiquitously expressed adaptor protein containing CRIB, SH3 and 14-3-3 interacting domains and has been shown to n
Autor:
Yujie Guo, Tingting Weng, Zhongming Chen, Nili Jin, Lin Liu, Jiwang Chen, Narendranath Reddy Chintagari, Manoj Bhaskaran, Li Gao
Publikováno v:
Free Radical Biology and Medicine. 43:628-642
Alveolar epithelial cell (AEC) injury and repair during hyperoxia exposure and recovery have been investigated for decades, but the molecular mechanisms of these processes are not clear. To identify potentially important genes involved in lung injury
Publikováno v:
genesis. 45:716-721
Mitogen-inducible gene 6 (Mig-6) is a stress-induced gene that serves as a negative regulator of epidermal growth factor (EGF) signaling and acts as a tumor suppressor. Ablation of Mig-6 results in a significant percentage of embryo lethality as well
Autor:
Narendranath Reddy Chintagari, Manoj Bhaskaran, Telugu Narasaraju, Nili Jin, Zhongming Chen, Lin Liu, Jiwang Chen
Publikováno v:
The Journal of Physiology. 572:625-638
The lung alveolar surface is covered by two morphologically and functionally distinct cells: alveolar epithelial cell types I and II (AEC I and II). The functions of AEC II, including surfactant release, cell differentiation and ion transport, have b
Publikováno v:
Cell and Tissue Research. 321:173-183
Although type A gamma-aminobutyric acid (GABA) receptors (ligand-gated Cl(-) channels) have been extensively studied in the central nervous system, no information is available on this receptor in lung cells. We have examined the expression of GABA(A)