Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Nili Avidan"'
Autor:
Rana Khsheibun, Tamar Paperna, Anat Volkowich, Izabella Lejbkowicz, Nili Avidan, Ariel Miller
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102331 (2014)
The effects of interferon-beta (IFN-β), one of the key immunotherapies used in multiple sclerosis (MS), on peripheral blood leukocytes and T cells have been extensively studied. B cells are a less abundant leukocyte type, and accordingly less is kno
Externí odkaz:
https://doaj.org/article/51da5319c1cd46cbbd058a2e0aec2dd2
Autor:
Noa Henig, Nili Avidan, Ilana Mandel, Elsebeth Staun-Ram, Elizabeta Ginzburg, Tamar Paperna, Ron Y Pinter, Ariel Miller
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62366 (2013)
BACKGROUND: Monocytes, which are key players in innate immunity, are outnumbered by neutrophils and lymphocytes among peripheral white blood cells. The cytokine interferon-β (IFN-β) is widely used as an immunomodulatory drug for multiple sclerosis
Externí odkaz:
https://doaj.org/article/203915761d7b4fdf8629bd981c0b7a94
Autor:
Jubran Boulos, Itai Ehrlich, Nili Avidan, Omer Shkedi, Lilac Haimovich-Caspi, Noam Kaplan, Izhak Kehat
It is essential to regulate the expression of genes, such as those encoding the proteins of the cardiac sarcomere. This regulation is often mediated by cis regulatory elements termed enhancers and repressors that recruit transcription factors to gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::833e66952a11d55af740ece4ab3fb9dc
https://doi.org/10.1101/2022.02.03.478957
https://doi.org/10.1101/2022.02.03.478957
Autor:
Marc H. De Baets, Sonia Berrih-Aknin, Laurent Servais, Frédérique Truffault, Nili Avidan, Bruno Eymard, Ariel Miller, Shimrat Mamrut, Mélinée Frenkian, Jiri Pitha, Elsebeth Staun-Ram, Tarek Sharshar
Publikováno v:
Journal of Autoimmunity, 82, 62-73. Elsevier Science
Objective: To identify novel genetic and epigenetic factors associated with Myasthenia gravis (MG) using an identical twins experimental study design.Methods: The transcriptome and methylome of peripheral monocytes were compared between mono zygotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea58756ea96530bb336a331a4f9c066a
https://ora.ox.ac.uk/objects/uuid:66d8358b-4df4-4093-8b5a-e7f074681ae4
https://ora.ox.ac.uk/objects/uuid:66d8358b-4df4-4093-8b5a-e7f074681ae4
Publikováno v:
Journal of Autoimmunity
Journal of Autoimmunity, Elsevier, 2014, 52, pp.146-153. ⟨10.1016/j.jaut.2013.12.001⟩
Journal of Autoimmunity, Elsevier, 2014, 52, pp.146-153. ⟨10.1016/j.jaut.2013.12.001⟩
Myasthenia gravis (MG) is a rare autoimmune disease characterized by the production of autoantibodies against proteins of the postsynaptic membrane in the neuromuscular junction. The estimated number of MG patients is steadily increasing, and it had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1e17b80c637739c5ba093838b0e3ac
Autor:
Orly Dgany, Nili Avidan, Ali Shamseddine, Paresh Vyas, Laila Zahed, Anne-Marie O'Hea, Aref Chehal, Hannah Tamary, Nicola Bienz, William G. Wood, Jacqui S. Beckmann, Joud H. Haidar, Momin Ahmed, Sunitha N. Wickramasinghe, Ali T. Taher, Douglas R. Higgs
The congenital dyserythropoietic anemias (CDAs) are a heterogeneous group of genetic disorders of erythropoiesis characterized by anemia secondary to ineffective erythropoiesis and striking morphologic abnormalities of erythroblasts (reviewed in Wick
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2470a98478a3168f56dc493093f58b73
https://ora.ox.ac.uk/objects/uuid:7d196392-4918-4b4e-88c1-85221bc91fcd
https://ora.ox.ac.uk/objects/uuid:7d196392-4918-4b4e-88c1-85221bc91fcd
Tailored therapeutics based on diagnostic tests—theranostics—is shaping future health care. We describe recent progress in the search for biomarkers for multiple sclerosis (MS) related to drug response. Robust and clinically validated predictive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db53a9dd35b39feaeeb87b257ff59de
https://doi.org/10.1016/b978-0-12-801914-6.00028-3
https://doi.org/10.1016/b978-0-12-801914-6.00028-3
Autor:
Sudha Veeraraghavan, Ralph J. Johnson, Dianna M. Milewicz, James T. Willerson, Van Tran-Fadulu, Dongchuan Guo, Eric Boerwinkle, Donna M. Muzny, Dong H. Kim, Ellen S. Regalado, Joseph S. Coselli, Christina L. Papke, Scott A. LeMaire, Ronald L. Dalman, Elizabeth Sparks, Anthony L. Estrera, James C. Grotta, Reed E. Pyeritz, Chander Raman, Ali J. Marian, Robert Yu, David A. Wheeler, Sanjay Shete, Steven E. Scherer, Nili Avidan, Hariyadarshi Pannu, Michael N. Singh, Marcia C. Willing, Lorraine Frazier, L. Maximilian Buja, Hazim J. Safi
Publikováno v:
The American Journal of Human Genetics. 84:617-627
The vascular smooth muscle cell (SMC)-specific isoform of alpha-actin (ACTA2) is a major component of the contractile apparatus in SMCs located throughout the arterial system. Heterozygous ACTA2 mutations cause familial thoracic aortic aneurysms and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec8ccf2af1c37831d9f671291e815dc
https://doi.org/10.1016/j.ajhg.2009.04.007
https://doi.org/10.1016/j.ajhg.2009.04.007
Autor:
Lea Glass-Marmor, Nili Avidan, Noa Tzunz-Henig, Ron Y. Pinter, Izabella Lejbkowicz, Ariel Miller, Tamar Paperna
Publikováno v:
Journal of the Neurological Sciences. 274:68-75
In recent years the realization that the concept 'one drug fits all' - does not work, created the need to shift gears from 'treating the disease' to 'treating the patient', and implementation of 'Personalized Medicine' where treatment is tailored to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a03a504057bb07f73930b5e5a89f49f
https://doi.org/10.1016/j.jns.2008.07.028
https://doi.org/10.1016/j.jns.2008.07.028
Autor:
Chul Ahn, Chander Raman, Steve Scherer, Christina L. Papke, Anthony L. Estrera, Van Tran-Fadulu, Richard A. Lewis, Robert Yu, Hariyadarshi Pannu, Colin E. Willoughby, Vivienne McConnell, Marcia C. Willing, Dong H. Kim, Sanjay Shete, Elizabeth Sparks, Nili Avidan, David J. Amor, Poyee P. Tung, Dianna M. Milewicz, Hazim J. Safi, Scott Bourgeois, Dongchuan Guo, L. Maximilian Buja, Lesley C. Adès, Dianne N. Abuelo
Publikováno v:
Nature Genetics. 39:1488-1493
The major function of vascular smooth muscle cells (SMCs) is contraction to regulate blood pressure and flow. SMC contractile force requires cyclic interactions between SMC alpha-actin (encoded by ACTA2) and the beta-myosin heavy chain (encoded by MY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d004d16d8ac0149b01cd661b19715c
https://doi.org/10.1038/ng.2007.6
https://doi.org/10.1038/ng.2007.6