Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nileshwari Vaghela"'
Autor:
Sonia Vallet, Loredana Santo, Jesse Schoonmaker, Edie Weller, Teru Hideshima, Hiroshi Ikeda, Diana Cirstea, Siddhartha Mukherjee, Nileshwari Vaghela, Nikhil C. Munshi, Wanling Xie, Noopur Raje, Yutaka Okawa, Samantha Pozzi, Eyal Rosen, Tanyel Kiziltepe, Mary L. Bouxsein, Kenneth C. Anderson
Publikováno v:
Clinical Cancer Research. 15:5829-5839
Purpose: The increasing incidence of osteonecrosis of the jaw and its possible association with high cumulative doses of bisphosphonate led us to study the effects of high doses of zoledronic acid (ZA) on bone remodeling. Experimental Design: Five-we
Autor:
Aliyah R. Sohani, Loredana Santo, Nileshwari Vaghela, David T. Scadden, Nikhil C. Munshi, Samantha Pozzi, Jesse Schoonmaker, Jasbir Seehra, Noopur Raje, Dharminder Chauhan, Edie Weller, Eyal C. Attar, Kenneth C. Anderson, Michael Churchill, Diana Cirstea, Teru Hideshima, Siddhartha Mukherjee, Ralph Weissleder, Sonia Vallet, A.R. Guimaraes, Wanling Xie, Mariateresa Fulciniti, Kishan Patel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(11)
Understanding the pathogenesis of cancer-related bone disease is crucial to the discovery of new therapies. Here we identify activin A, a TGF-β family member, as a therapeutically amenable target exploited by multiple myeloma (MM) to alter its micro
Autor:
Nileshwari Vaghela, Mario Boccadoro, Shweta Chhetri, Klaus Podar, Diana Cirstea, Noopur Raje, Samantha Pozzi, Kenji Ishitsuka, Janice Jin, Yutaka Okawa, Siddhartha Mukherjee, Hiroshi Yasui, Teru Hideshima, Sonia Vallet, Tanyel Kiziltepe, Hiroshi Ikeda, Enrique M. Ocio, Norihiko Shiraishi, Iris Breitkreutz, Kenneth C. Anderson, Marco Ladetto
The interaction between osteoclasts (OCs) and multiple myeloma (MM) cells plays a key role in the pathogenesis of MM-related osteolytic bone disease (OBD). MM cells promote OC formation and, in turn, OCs enhance MM cell proliferation. Chemokines are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d7e835ea6572c40ee4f7c7afa0e4cf
https://europepmc.org/articles/PMC2077320/
https://europepmc.org/articles/PMC2077320/
Autor:
Gullu Gorgun, NC Munshi, Diana Cirstea, Noopur Raje, Elisabetta Calabrese, Giulia Perrone, Sonia Vallet, Yutaka Okawa, H Loferer, Nileshwari Vaghela, Kishan Patel, G Motyckova, KC Anderson, Teru Hideshima, Samantha Pozzi, Hiroshi Ikeda, Loredana Santo
Publikováno v:
Clinical Lymphoma and Myeloma. 9:S139-S140
Autor:
KC Anderson, Kishan Patel, G Motyckova, Gullu Gorgun, Diana Cirstea, Scott J. Rodig, Yutaka Okawa, Elisabetta Calabrese, N Desai, V Trieu, Noopur Raje, Samantha Pozzi, Hiroshi Ikeda, Giulia Perrone, Loredana Santo, Sonia Vallet, Peter Sportelli, NC Munshi, T Currie, Nileshwari Vaghela, Teru Hideshima
Publikováno v:
Clinical Lymphoma and Myeloma. 9:S138-S139
Autor:
Chirayu G. Patel, Siddhartha Mukherjee, NC Munshi, Teru Hideshima, Jesse Schoonmaker, Jasbir Seehra, Edie Weller, Nileshwari Vaghela, Sonia Vallet, Loredana Santo, KC Anderson, David T. Scadden, Eyal C. Attar, Noopur Raje, Wanling Xie, Mariateresa Fulciniti, Aliyah Rahemtullah, Samantha Pozzi, Diana Cirstea
Publikováno v:
Clinical Lymphoma and Myeloma. 9:S126-S127
Autor:
Gullu Gorgun, Samantha Pozzi, Loredana Santo, Mario Boccadoro, Noopur Raje, T Cirstea, NC Munshi, Hiroshi Ikeda, Nileshwari Vaghela, Teru Hideshima, KC Anderson, Marco Ladetto, Sonia Vallet, Yutaka Okawa, Squires
Publikováno v:
Clinical Lymphoma and Myeloma. 9:S137-S138
Autor:
Jesse Schoonmaker, Samantha Pozzi, Aliyah Rahemtullah, Alexander R. Guimaraes, Michael Churchill, David T. Scadden, Diana Cirstea, Teru Hideshima, Noopur Raje, Kenneth C. Anderson, Eyal C. Attar, Nileshwari Vaghela, Nikhil C. Munshi, Dharminder Chauhan, Sonia Vallet, Kishan Patel, Wanling Xie, Mariateresa Fulciniti, Chirayu G. Patel, Loredana Santo, Jasbir Seehra, Edie Weller, Siddhartha Mukherjee
Publikováno v:
ResearcherID
Abstract 1789 Poster Board I-815 Understanding the pathogenesis of cancer-related bone disease is critical to the discovery of new therapies. The development of osteolytic lesions in multiple myeloma (MM) results from unopposed osteoclast activity du
Autor:
Mariateresa Fulciniti, Diana Cirstea, Teru Hideshima, David T. Scadden, Siddhartha Mukherjee, Kishan Patel, Samantha Pozzi, Petter Veiby, Noopur Raje, Loredana Santo, Nileshwari Vaghela, Kenneth C. Anderson, Sonia Vallet
Publikováno v:
Blood. 114:739-739
Abstract 739 A common feature of bone disease in cancer is hyperactivity of osteoclasts (OC). However, osteoblast (OB) inhibition is critical to the development of osteolytic lesions. Tumor-OC interactions have been extensively studied, the mechanism
Autor:
David T. Scadden, KC Anderson, Samantha Pozzi, Stuart Kuhstoss, Noopur Raje, Kishan Patel, Mariateresa Fulciniti, Diana Cirstea, Siddhartha Mukherjee, Sonia Vallet, Loredana Santo, Nileshwari Vaghela, Teru Hideshima, H Yan, L Schirtzinger
Publikováno v:
Clinical Lymphoma and Myeloma. 9:S111