Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Nilesh Sudhakar, Ambhore"'
Autor:
Nilesh Sudhakar Ambhore, Premanand Balraj, Ashish Kumar, Mohammad Irshad Reza, Yogaraj S. Ramakrishnan, Jacob Tesch, Sahil Lohana, Venkatachalem Sathish
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background In asthma, sex-steroids signaling is recognized as a critical regulator of disease pathophysiology. However, the paradoxical role of sex-steroids, especially estrogen, suggests that an upstream mechanism or even independent of est
Externí odkaz:
https://doaj.org/article/1374b887534941a691c4103e49c319ef
Autor:
Barbara Ruaro, Riccardo Pozzan, Alessia Giovanna Andrisano, Marco Confalonieri, Nilesh Sudhakar Ambhore
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/594716896b9746bc9160386d60753197
Autor:
Priyanka Banerjee, Premanand Balraj, Nilesh Sudhakar Ambhore, Sarah A. Wicher, Rodney D. Britt, Christina M. Pabelick, Y. S. Prakash, Venkatachalem Sathish
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Airway smooth muscle (ASM) is known for its role in asthma exacerbations characterized by acute bronchoconstriction and remodeling. The molecular mechanisms underlying multiple gene interactions regulating gene expression in asthma remain el
Externí odkaz:
https://doaj.org/article/8b34563885034ee5adaba98fb6aef59d
Autor:
Niyati A. Borkar, Nilesh Sudhakar Ambhore, Rama Satyanarayana Raju Kalidhindi, Christina M. Pabelick, Y.S. Prakash, Venkatachalem Sathish
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Sex and gender disparity in asthma is recognized and suggests a modulatory role for sex steroids, particularly estrogen. However, there is a dichotomous role for estrogen in airway remodeling, making it unclear whether sex hormones are protective or
Externí odkaz:
https://doaj.org/article/b370b7edd28042ea9617b99dd9c2c7bc
Autor:
Rama Satyanarayana Raju Kalidhindi, Nilesh Sudhakar Ambhore, Sangeeta Bhallamudi, Jagadish Loganathan, Venkatachalem Sathish
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2020)
Epidemiological data suggests increased prevalence of asthma in females than males, suggesting a plausible role for sex-steroids, especially estrogen in the lungs. Estrogen primarily acts through estrogen-receptors (ERα and ERβ), which play a diffe
Externí odkaz:
https://doaj.org/article/4d3b5000f8e14b25be88f6cbb7a699a0
Autor:
Niyati A Borkar, Nilesh Sudhakar Ambhore, Premanand Balraj, Yogaraj S Ramakrishnan, Venkatachalem Sathish
Publikováno v:
The Journal of Pathology.
Autor:
Rodney D. Britt, Y. S. Prakash, Venkatachalem Sathish, Christina M. Pabelick, S.A. Wicher, Priyanka Banerjee, Nilesh Sudhakar Ambhore, Premanand Balraj
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Airway smooth muscle (ASM) is known for its role in asthma exacerbations characterized by acute bronchoconstriction and remodeling. The molecular mechanisms underlying multiple gene interactions regulating gene expression in asthma remain elusive. He
Autor:
Taylor Schmidt, Rama Satyanarayana Raju Kalidhindi, Premanand Balraj, Venkatachalem Sathish, Nilesh Sudhakar Ambhore, M. Nadeem Khan
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Epidemiological studies demonstrate an apparent sex-based difference in the prevalence of asthma, with a higher risk in boys than girls, which is reversed postpuberty, where women become more prone to asthma than men, suggesting a plausible beneficia
Autor:
Venkatachalem Sathish, Nilesh Sudhakar Ambhore, Rama Satyanarayana Raju Kalidhindi, Christina M. Pabelick, Y. S. Prakash, Niyati A. Borkar
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
The incidence, severity, and mortality of ongoing coronavirus infectious disease 19 (COVID-19) is greater in men compared with women, but the underlying factors contributing to this sex difference are still being explored. In the current study, using
Autor:
Shubhashri Mohire, K. Elango, Mahesh Thondawada, Karthik Yamjala, Vishakantha Murthy, Nilesh Sudhakar Ambhore, Shashank Mulukutla, Rama Satyanarayana Raju Kalidhindi
Publikováno v:
Journal of Young Pharmacists. 12:55-62
Objectives: Epidemiological data suggests the highest density of histamine H3-receptors (H3R) in basal ganglia of central nervous system (CNS) wherein they function as inhibitory auto-receptors and control the release of many neurotransmitters. Inhib