In silico, in vitro and in vivo characterization of host-associated Latilactobacillus curvatus strains for potential probiotic applications in farmed Atlantic salmon (Salmo salar)

Autor: Hannah S. Cathers, Shrinivasrao P. Mane, Nilesh R. Tawari, Jayanth Balakuntla, Germán Plata, Madan Krishnamurthy, Alicia MacDonald, Marilyn Wolter, Niel Baxter, Julian Briones, Akshitha Nagireddy, Gregory Millman, Roberto E. Martin, Arvind Kumar (Mahajan), Dharanesh Gangaiah

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)

Abstract Salmon aquaculture is the fastest growing animal protein production system in the world; however, intensive farming leads to poor weight gain, stress, and disease outbreaks. Probiotics offer the potential to enhance growth performance and fe

Externí odkaz: https://doaj.org/article/c80f24ede0294ad2a32b79ba15cf0ebe

Whole-Genome Resequencing Identifies the Molecular Genetic Cause for the Absence of a Gy5 Glycinin Protein in Soybean PI 603408

Autor: Jason D. Gillman, Won-Seok Kim, Bo Song, Nathan W. Oehrle, Nilesh R. Tawari, Shanshan Liu, Hari B. Krishnan

Publikováno v: G3: Genes, Genomes, Genetics, Vol 7, Iss 7, Pp 2345-2352 (2017)

During ongoing proteomic analysis of the soybean (Glycine max (L.) Merr) germplasm collection, PI 603408 was identified as a landrace whose seeds lack accumulation of one of the major seed storage glycinin protein subunits. Whole genomic resequencing

Externí odkaz: https://doaj.org/article/d992c1dbce764612909ab278b96f870d

Singapore Undiagnosed Disease Program: Genomic Analysis aids Diagnosis and Clinical Management

Autor: Breana Cham, Jiin Ying Lim, Wendy K.M. Liew, Yuen-Ming Tan, Jyn-Ling Kuan, Bruno Reversades, Raman Sethi, Alvin Yu Jin Ng, Nathalie Escande-Beillard, Alexander Lezhava, Sumanty Tohari, Heming Wei, Arun George Devasia, Deepa Subramanian, Sylvia Kam, Woei Kang Liew, Min Xie, Kanika Jain, Saumya Shekhar Jamuar, Hai-Yang Law, Ee Shien Tan, Nilesh R. Tawari, Swati Tomar, Ene-Choo Tan, Ivy Ng, Carine Bonnard, Grace Lin, Angeline Lai, Chew Yin Jasmine Goh, Perumal Dharuman, Poh San Lai, Arthi Shanmugasundaram, Huilin Chin, Neha Singh Bhatia, Denise L.M. Goh, Maggie Brett, Célia Bosso-Lefèvre, Grace K. Tan, Teck Wah Ting, Roger Foo, Sarah B Ng, Cheuk Ka Tong, Byrappa Venkatesh, Zenia Tiang

Publikováno v: Archives of Disease in Childhood. 106:31-37

ObjectiveUse next-generation sequencing (NGS) technology to improve our diagnostic yield in patients with suspected genetic disorders in the Asian setting.DesignA diagnostic study conducted between 2014 and 2019 (and ongoing) under the Singapore Undi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bba7015302a03439efc4b46889a6c9
https://doi.org/10.1136/archdischild-2020-319180

The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels

Autor: Shrinivas Mane, Alberto Del Rio-Espinola, Åsa Ohlsson, Åke Hedhammar, Philippe Gruet, Jens Häggström, Mats E. Pettersson, Nilesh R. Tawari, Erik Axelsson, Troy Hawkins, Karolina Engdahl, Lisbeth H. Olsen, Ingrid Ljungvall, Ragnvi Hagman, Dmytro Kryvokhyzha, Olivier Grenet, Jeanette Hanson, Eva Murén, Jonathan G. Moggs, Kerstin Lindblad-Toh, Priyasma Bhoumik, Laura Bas Conn, Christian Epe, Bruce Taillon

Publikováno v: Axelsson, E, Ljungvall, I, Bhoumik, P, Conn, L B, Muren, E, Ohlsson, Å, Olsen, L H, Engdahl, K, Hagman, R, Hanson, J, Kryvokhyzha, D, Pettersson, M, Grenet, O, Moggs, J, Del Rio-Espinola, A, Epe, C, Taillon, B, Tawari, N, Mane, S, Hawkins, T, Hedhammar, Å, Gruet, P, Häggström, J & Lindblad-Toh, K 2021, ' The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels : [+ correction] ', PLOS Genetics, vol. 17, no. 9, e1009726 . https://doi.org/10.1371/journal.pgen.1009726
PLoS Genetics, 17 (9)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 9, p e1009726 (2021)

Selective breeding for desirable traits in strictly controlled populations has generated an extraordinary diversity in canine morphology and behaviour, but has also led to loss of genetic variation and random entrapment of disease alleles. As a conse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da38d6d836f08dd0ce14e097ac93696

Reanalysis of genome sequences of tomato accessions and its wild relatives: development of Tomato Genomic Variation (TGV) database integrating SNPs and INDELs polymorphisms

Autor: Sameera Devulapalli, Rameshwar Sharma, Yellamaraju Sreelakshmi, Nilesh R. Tawari, Prateek K. Gupta, Pankaj Singh Dholaniya

Publikováno v: Bioinformatics (Oxford, England). 36(20)

MotivationFacilitated by technological advances and expeditious decrease in the sequencing costs, whole-genome sequencing (WGS) is increasingly implemented to uncover variations in cultivars/accessions of many crop plants. In tomato (Solanum lycopers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334ad696c1eb0c838760bc314e576ea3
https://pubmed.ncbi.nlm.nih.gov/32829394