Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nilesh J. Bokil"'
Autor:
Lin Luo, Nilesh J. Bokil, Adam A. Wall, Ronan Kapetanovic, Natalie M. Lansdaal, Faustine Marceline, Belinda J. Burgess, Samuel J. Tong, Zhong Guo, Kirill Alexandrov, Ian L. Ross, Margaret L. Hibbs, Jennifer L. Stow, Matthew J. Sweet
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Toll-like receptors engage TIR domain-containing adaptors to control proinflammatory gene expression in response to pathogens and tissue damage. Here the authors show that the non-TIR domain-containing transmembrane protein SCIMP is a previously unre
Externí odkaz:
https://doaj.org/article/836a68fa90214766a1565bfa90175cad
Autor:
Jessica L Pedersen, Simone E Barry, Nilesh J Bokil, Magda Ellis, YuRong Yang, Guangyu Guan, Xiaolin Wang, Alen Faiz, Warwick J Britton, Bernadette M Saunders
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract Objectives Non‐sputum‐based tests to accurately identify active tuberculosis (TB) disease and monitor response to therapy are urgently needed. This study examined the biomarker capacity of a panel of plasma proteins alone, and in conjunc
Externí odkaz:
https://doaj.org/article/f867fb630b26495eb9943fc9365a6dbb
Autor:
James EB Curson, Lin Luo, Liping Liu, Belinda J Burgess, Nilesh J Bokil, Adam A Wall, Tomas Brdicka, Ronan Kapetanovic, Jennifer L Stow, Matthew J Sweet
Publikováno v:
Immunology & Cell Biology. 100:267-284
Toll-like receptor (TLR) signaling relies on Toll/interleukin-1 receptor homology (TIR) domain-containing adaptor proteins that recruit downstream signaling molecules to generate tailored immune responses. In addition, the palmitoylated transmembrane
Autor:
Nilesh J. Bokil, Warwick J. Britton, Bernadette M. Saunders, Guy B. Marks, Jennifer Ho, Greg J. Fox, Phuong Thi Bich Nguyen, Nathan J. Hare, Thu Anh Nguyen, Michael Liu
Publikováno v:
Journal of Infection. 81:72-80
Summary Objectives Global tuberculosis (TB) control is restricted by the failure to detect an estimated 3.3 million TB cases annually. In the majority of TB endemic settings, sputum smear microscopy is used to diagnose TB, but this test is insensitiv
Autor:
Kate M. Peters, Ronan Kapetanovic, Claudia J. Stocks, James E. B. Curson, Nilesh J. Bokil, Darren Foo, Minh-Duy Phan, Jessica B. von Pein, Robert G. Parton, Matthew J. Sweet, Mark A. Schembri, Taiho Kambe, James Rae
Publikováno v:
Journal of Leukocyte Biology
TLR‐inducible zinc toxicity is an antimicrobial mechanism utilized by macrophages, however knowledge of molecular mechanisms mediating this response is limited. Here, we show that E. coli exposed to zinc stress within primary human macrophages resi
Autor:
Morten Thaysen-Andersen, Rebeca Kawahara, Alexander Pralow, Bernadette M. Saunders, Nilesh J. Bokil, Jessica L Pedersen, Hannes Hinneburg, Erdmann Rapp, Falko Schirmeister
Publikováno v:
Glycobiology. 30:679-694
Protein glycosylation impacts the development and function of innate immune cells. The glycophenotypes and the glycan remodelling associated with the maturation of macrophages from monocytic precursor populations remain incompletely described. Herein
Autor:
Warwick J. Britton, Simone E. Barry, Yu Rong Yang, Xiaolin Wang, Nilesh J. Bokil, Magda K. Ellis, Jessica L Pedersen, Alen Faiz, Bernadette M. Saunders, Guangyu Guan
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Clinical & Translational Immunology
Clinical & Translational Immunology
Objectives Non‐sputum‐based tests to accurately identify active tuberculosis (TB) disease and monitor response to therapy are urgently needed. This study examined the biomarker capacity of a panel of plasma proteins alone, and in conjunction with
© 2019 Elsevier Ltd Efforts to reduce the global TB burden are hindered by the lack of simple, reliable non-sputum based diagnostics. To date studies investigating the biomarker potential of circulating host proteins and mRNA have not shown sufficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17e966199e065a9ab2e36b53a37785c
https://hdl.handle.net/10453/135875
https://hdl.handle.net/10453/135875
Autor:
Ronan Kapetanovic, Bernadette M. Saunders, Maud E. S. Achard, Katryn J. Stacey, Minh-Duy Phan, Matthew J. Sweet, Kate M. Peters, Mark A. Schembri, Cheryl-lynn Y. Ong, Mercedes Monteleone, Nilesh J. Bokil, Mark J. Walker, Claudia J. Stocks, Katharine M. Irvine, Alastair G. McEwan, Kate Schroder
Publikováno v:
The FASEB Journal. 30:1901-1912
We aimed to characterize antimicrobial zinc trafficking within macrophages and to determine whether the professional intramacrophage pathogen Salmonella enterica serovar Typhimurium (S Typhimurium) subverts this pathway. Using both Escherichia coli a
Autor:
Timothy Ravasi, Makrina Totsika, Kolja Schaale, Charalampos Harris Mavromatis, Asha Kakkanat, Carlo Vittorio Cannistraci, Nilesh J. Bokil, Scott A. Beatson, Matthew J. Sweet, Mark A. Schembri, Taewoo Ryu, Glen C. Ulett
Publikováno v:
Cellular Microbiology
Summary Urinary tract infections (UTI) are among the most common infections in humans. Uropathogenic E scherichia coli (UPEC) can invade and replicate within bladder epithelial cells, and some UPEC strains can also survive within macrophages. To unde