Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nilesh Gaud"'
Autor:
Mirosława Gładysz, Maciej Rogacki, Łukasz Dudek, Kinga Michalik, Jolanta Mazurek, Marcin Leś, Aleksandra Poczkaj, Peter Littlewood, Krzysztof Brzózka, Aniela Golas, Stefan Chmielewski, Justyna Jabłońska, Raghuram Tangirala, Magnus Widegren, Kamil Kuś, Urszula Głowniak-Kwitek, Nilesh Gaud, Izabela Strojny, Katarzyna Dziedzic, Arkadiusz Białas, Magdalena Zawadzka, Grzegorz Ćwiertnia
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A799-A799
BackgroundSTimulator of INterferon Genes (STING) is a key signaling protein involved in activation of the immune system in response to self-DNA. In recent years, STING signaling has been demonstrated to play a major role in activating the antitumor i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c00502def4d384b672f8d068e4507738
https://doi.org/10.1136/jitc-2021-sitc2021.764
https://doi.org/10.1136/jitc-2021-sitc2021.764
Autor:
Prashant Kole, Anoop Kumar, Sandhya Mandlekar, Vinay K. Holenarsipur, Nilesh Gaud, Muralikrishna Matta, Srikanth Sridhar
Publikováno v:
European Journal of Pharmaceutical Sciences. 99:272-278
Rat is commonly used for pharmacokinetic screening during pharmaceutical lead optimization. To handle the large number of compounds, rats with a single jugular vein cannulation are commonly utilized for intravenous pharmacokinetic studies, where the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e510d42829b1bfb60578226d7216672f
https://doi.org/10.1016/j.ejps.2016.12.025
https://doi.org/10.1016/j.ejps.2016.12.025
Autor:
Vinay K. Holenarsipur, Robert Langish, Jun Dai, Petia Shipkova, Yaofeng Cheng, Nilesh Gaud, Sabariya Selvam, Sandhya Mandlekar, Prabhakar Rajanna, Onkar Date, Senthilkumar Murugesan, Hong Shen, Yurong Lai, Punit Marathe, William G. Humphreys
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 358:397-404
In the present study, an open-label, three-treatment, three-period clinical study of rosuvastatin (RSV) and rifampicin (RIF) when administered alone and in combination was conducted in 12 male healthy subjects to determine if coproporphyrin I (CP-I)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2cb8ca6157a8822d34a80fec7887e81
https://doi.org/10.1124/jpet.116.234914
https://doi.org/10.1124/jpet.116.234914
Autor:
Nilesh Gaud, Tarun Sharma, Punit Marathe, Sheelendra Pratap Singh, Sundeep Paruchury, Sandhya Mandlekar, Rambabu Arla, Murali Subramanian, Vinay K. Holenarsipur, Priyadeep Bhutani, Sankara Sivaprasad, Jaydeep Sinha
Publikováno v:
Biopharmaceutics & Drug Disposition. 36:385-397
In recent years prodrug strategy has been used extensively to improve the pharmacokinetic properties of compounds exhibiting poor bioavailability. Mechanistic understanding of the absorption and the role of intestine and liver in the activation of or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401d16c45f093a8780ed7da6e0f53970
https://doi.org/10.1002/bdd.1950
https://doi.org/10.1002/bdd.1950
Autor:
Vinay K, Holenarsipur, Nilesh, Gaud, Jaydeep, Sinha, Sankara, Sivaprasad, Priyadeep, Bhutani, Murali, Subramanian, Sheelendra Pratap, Singh, Rambabu, Arla, Sundeep, Paruchury, Tarun, Sharma, Punit, Marathe, Sandhya, Mandlekar
Publikováno v:
Biopharmaceuticsdrug disposition. 36(6)
In recent years prodrug strategy has been used extensively to improve the pharmacokinetic properties of compounds exhibiting poor bioavailability. Mechanistic understanding of the absorption and the role of intestine and liver in the activation of or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee324df7f66f4693a7782827b0e6679c
https://pubmed.ncbi.nlm.nih.gov/25832562
https://pubmed.ncbi.nlm.nih.gov/25832562
Publikováno v:
Laboratory animals. 44(3)
The zinc disc implantation-induced urinary bladder calculi model in the rat is commonly used for preclinical evaluation of the antiurolithiatic activity of test compounds. Certain published reports state that relatively long durations for which zinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806410b5feb949c2c9035f8088fb0ab7
https://pubmed.ncbi.nlm.nih.gov/20385652
https://pubmed.ncbi.nlm.nih.gov/20385652
Autor:
Gabor-Worwa, Ewelina, Kowal-Chwast, Anna, Gaud, Nilesh, Gogola, Dawid, Littlewood, Peter, Smoluch, Marek, Brzózka, Krzysztof, Kus, Kamil
Publikováno v:
European Journal of Drug Metabolism & Pharmacokinetics; May2024, Vol. 49 Issue 3, p393-403, 11p
Publikováno v:
Clinical Pharmacology & Therapeutics; Feb2023, Vol. 113 Issue 2, p212-217, 6p
Publikováno v:
Drug Week; 9/6/2024, p1969-1969, 1p