Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nilda E, Rodríguez"'
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Worldwide, an estimated 12 million people are infected with Leishmania spp. and an additional 350 million are at risk of infection. Leishmania are intracellular parasites that cause disease by suppressing macrophage microbicidal responses. Infection
Externí odkaz:
https://doaj.org/article/84db6537304a4499a7de2f860affd7d4
Publikováno v:
Exp Parasitol
The parasitic protozoan Leishmania infantum resides primarily in macrophages throughout mammalian infection. Infection is initiated by deposition of the metacyclic promastigote into the dermis of a mammalian host by the sand fly vector. Promastigotes
Autor:
Ryan D. Lockard, Selma M. B. Jeronimo, Eliana L. Nascimento, Mary E. Wilson, Upasna Gaur Dixit, Nilda E. Rodríguez, Hemali Batra-Sharma, Iraci D. Lima, Elizabeth A. Turcotte
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 98:142-145
Leishmania infantum causes visceral leishmaniasis (VL) in Brazil. We previously observed that VL is more common in males than females living in endemic neighborhoods, despite similar exposure. Using a larger sample, we document that VL is more common
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19000 (2011)
The life stages of Leishmania spp. include the infectious promastigote and the replicative intracellular amastigote. Each stage is phagocytosed by macrophages during the parasite life cycle. We previously showed that caveolae, a subset of cholesterol
Externí odkaz:
https://doaj.org/article/c5c12e680d6140a485dd2a25a6da259b
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Journal of Immunology Research
Journal of Immunology Research
Worldwide, an estimated 12 million people are infected with Leishmania spp. and an additional 350 million are at risk of infection. Leishmania are intracellular parasites that cause disease by suppressing macrophage microbicidal responses. Infection
Autor:
Nilda E, Rodríguez, Iraci D, Lima, Upasna, Gaur Dixit, Elizabeth A, Turcotte, Ryan D, Lockard, Hemali, Batra-Sharma, Eliana L, Nascimento, Selma M B, Jeronimo, Mary E, Wilson
Publikováno v:
The American journal of tropical medicine and hygiene. 98(1)
Leishmania infantum causes visceral leishmaniasis (VL) in Brazil. We previously observed that VL is more common in males than females living in endemic neighborhoods, despite similar exposure. Using a larger sample, we document that VL is more common
Publikováno v:
Cellular Microbiology. 11:1827-1841
The obligate intracellular protozoan, Leishmania infantum chagasi (Lic) undergoes receptor-mediated phagocytosis by macrophages, followed by a transient delay in phagolysosome maturation. We found differences in the pathway through which virulent Lic
Publikováno v:
Cellular Microbiology. 8:1106-1120
Summary Caveolae are membrane microdomains enriched in cholesterol, ganglioside M1 (GM1) and caveolin-1. We explored whether caveolae facilitate the entry of Leishmania chagasi into murine macrophages. Tran- sient depletion of macrophage membrane cho
Publikováno v:
Infection and Immunity. 72:2111-2122
Leishmaniaspp. are protozoans that survive and replicate intracellularly in mammalian macrophages. Antileishmanial immunity requires gamma interferon (IFN-γ)-mediated macrophage activation and generation of microbicidal effector molecules. The prese
Autor:
Thomas J. Recker, Eliana T. Nascimento, Stacey Schultz-Cherry, Nilda E. Rodríguez, Mary E. Wilson, Todd L. Goldman, Melissa A. Miller, Selma M. B. Jeronimo, Kira R. Gantt
Publikováno v:
The Journal of Immunology. 170:2613-2620
TGF-β is a potent regulatory cytokine that suppresses expression of inducible NO synthase and IFN-γ, and suppresses Th1 and Th2 cell development. We examined whether functionally active TGF-β is present in the local environment surrounding the inv