Zobrazeno 1 - 10
of 808
pro vyhledávání: '"Nilanjana, Maulik"'
Autor:
Andrew Kemerley, Abhishek Gupta, Mahesh Thirunavukkarasu, Monica Maloney, Sean Burgwardt, Nilanjana Maulik
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 1904-1920 (2024)
The SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) virus and the resulting COVID-19 pandemic have had devastating and lasting impact on the global population. Although the main target of the disease is the respiratory tract, clinical ou
Externí odkaz:
https://doaj.org/article/4193e0f0c0c74b969e9c9c9bba9cbb85
Autor:
Mahesh Thirunavukkarasu, Santosh Swaminathan, Andrew Kemerley, Seetur R. Pradeep, Sue Ting Lim, Diego Accorsi, Rickesha Wilson, Jacob Campbell, Ibnalwalid Saad, Siu-Pok Yee, J. Alexander Palesty, David W. McFadden, Nilanjana Maulik
Publikováno v:
Cells, Vol 12, Iss 11, p 1527 (2023)
Objectives: Intra-abdominal sepsis is commonly diagnosed in the surgical population and remains the second most common cause of sepsis overall. Sepsis-related mortality remains a significant burden in the intensive care unit despite advances in criti
Externí odkaz:
https://doaj.org/article/a934038cd1a44ee48250cd648ac486d1
Autor:
Subhadip Ghatak, Savita Khanna, Sashwati Roy, Mahesh Thirunavukkarasu, Seetur R. Pradeep, Brian C. Wulff, Mohamed S. El Masry, Anu Sharma, Ravichand Palakurti, Nandini Ghosh, Yi Xuan, Traci A. Wilgus, Nilanjana Maulik, Mervin C. Yoder, Chandan K. Sen
Publikováno v:
Molecular Therapy. 31:454-470
Fetal cutaneous wound closure and repair differ from that in adulthood. In this work, we identify an oxidant stress sensor protein, nonselenocysteine-containing phospholipid hydroperoxide glutathione peroxidase (NPGPx), that is abundantly expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185fb23bbad5882c23bdca816e83c17d
https://doi.org/10.1016/j.ymthe.2022.09.002
https://doi.org/10.1016/j.ymthe.2022.09.002
Autor:
Mahesh Thirunavukkarasu, Vaithinathan Selvaraju, Mandip Joshi, Vladimir Coca‐Soliz, Leonidas Tapias, IbnalWalid Saad, Craig Fournier, Aaftab Husain, Jacob Campbell, Siu‐Pok Yee, Juan A. Sanchez, J. Alexander Palesty, David W. McFadden, Nilanjana Maulik
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 18 (2018)
Background The present study demonstrates that the ubiquitin E3 ligase, Pellino‐1 (Peli1), is an important angiogenic molecule under the control of vascular endothelial growth factor (VEGF) receptor 2/Flk‐1. We have previously reported increased
Externí odkaz:
https://doaj.org/article/9134b53757234dfdba8213340f4c0907
Autor:
Seetur R Pradeep, Sue Ting Lim, Mahesh Thirunavukkarasu, Mandip Joshi, Bryan Cernuda, J Alexander Palesty, Nilanjana Maulik
Publikováno v:
Journal of the American College of Surgeons. 235(2)
Our earlier studies showed that inhibiting prolyl-4-hydroxylase enzymes (PHD-1 and PHD-3) improves angiogenesis, heart function, and limb perfusion in mouse models via stabilizing hypoxia-inducible transcription factor-alpha (HIF-1α). The present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620e1ea93a05f8bdff89f7dce7fd29b2
https://pubmed.ncbi.nlm.nih.gov/35839399
https://pubmed.ncbi.nlm.nih.gov/35839399
Autor:
Sue-Ting Lim, Seetur R Pradeep, Mahesh Thirunavukkarasu, Santosh Swaminathan, Diego Accorsi, J Alexander Palesty, Nilanjana Maulik
Publikováno v:
Circulation. 144
Introduction: Increased production of reactive oxygen species contributes to the etiology of diabetic complications. It acts as an intracellular antioxidant by scavenging reactive oxygen species (ROS) and protect the cells against oxidative stress an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f221d0fa5b48c89536964fc3409d160
https://doi.org/10.1161/circ.144.suppl_1.11457
https://doi.org/10.1161/circ.144.suppl_1.11457
Autor:
Shikhar Mehrotra, Xue-Zhong Yu, Anusara Daenthanasanmak, Supinya Iamsawat, Junfei Jin, M. Hanief Sofi, Jessica Heinrichs Voss, David Bastian, Shanmugam Panneer Selvam, Steven Schutt, Besim Ogretmen, Nilanjana Maulik, Yongxia Wu, Min Dai, Hung Nguyen, Chen Liu
Publikováno v:
Journal of Clinical Investigation. 129:2760-2774
Oxidative stress is elevated in the recipients of allogeneic hematopoietic transplantation (allo-HCT) and likely contributes to the development of graft-versus-host disease (GVHD). GVHD is characterized by activation, expansion, cytokine production a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b30d650c900dbee45d94ffecdd5c039
https://doi.org/10.1172/jci122899
https://doi.org/10.1172/jci122899
Autor:
Vamsi K. Gangaraju, Shikhar Mehrotra, Besim Ogretmen, Gary Hardiman, Annika Dalheim, Nilanjana Maulik, Supinya Iamsawat, Paramita Chakraborty, Elizabeth G. Hill, Shilpak Chatterjee, Pravin Kesarwani, Gina Scurti, Shanmugam Panneer Selvam, Hung Nguyen, Xue-Zhong Yu, Nancy Klauber-DeMore, Krishnamurthy Thyagarajan, Mark P. Rubinstein, Patrick Nasarre, Lauren E. Ball, Michael I. Nishimura
Publikováno v:
J Biol Chem
Adoptive transfer of tumor epitope–reactive T cells has emerged as a promising strategy to control tumor growth. However, chronically-stimulated T cells expanded for adoptive cell transfer are susceptible to cell death in an oxidative tumor microen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed84919875ad357535de5e545361c84
https://doi.org/10.1074/jbc.ra118.006753
https://doi.org/10.1074/jbc.ra118.006753
Publikováno v:
Proinflammatory and Antiinflammatory Peptides ISBN: 9781003064695
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70bde87e0145268fe3d729124096528a
https://doi.org/10.1201/9781003064695-17
https://doi.org/10.1201/9781003064695-17
Autor:
Diego Accorsi, Seetur R. Pradeep, Santosh Swaminathan, Nilanjana Maulik, Mahesh Thirunavukkarasu, J. Alexander Palesty, Jacob Campbell, Rickesha I Wilson
Publikováno v:
Circulation. 142
Introduction: Sepsis remains a significant cause of mortality in the intensive care unit till today. Recent research suggests nearly one in four deaths in people with heart failure is caused by sepsis. Overexpression of mammalian Pellino-1 (Peli1), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989c4991f2382c4bb8f528eee65ef113
https://doi.org/10.1161/circ.142.suppl_3.14673
https://doi.org/10.1161/circ.142.suppl_3.14673