Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nilakshee Bhattacharya"'
Autor:
Mario Mietzsch, J. Kennon Smith, Jennifer C. Yu, Vibhu Banala, Shanan N. Emmanuel, Ariana Jose, Paul Chipman, Nilakshee Bhattacharya, Robert McKenna, Mavis Agbandje-McKenna
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 362-373 (2020)
Affinity-based purification of adeno-associated virus (AAV) vectors has replaced density-based methods for vectors used in clinical settings. This method utilizes camelid single-domain antibodies recognizing AAV capsids. These include AVB Sepharose (
Externí odkaz:
https://doaj.org/article/28d7c2f26301459a88a2ed347f353059
Autor:
Jennifer Chun Yu, Mario Mietzsch, Amriti Singh, Alberto Jimenez Ybargollin, Shweta Kailasan, Paul Chipman, Nilakshee Bhattacharya, Julia Fakhiri, Dirk Grimm, Amit Kapoor, Indrė Kučinskaitė-Kodzė, Aurelija Žvirblienė, Maria Söderlund-Venermo, Robert McKenna, Mavis Agbandje-McKenna
Publikováno v:
Viruses, Vol 13, Iss 2, p 330 (2021)
Human bocavirus 1 (HBoV1) has gained attention as a gene delivery vector with its ability to infect polarized human airway epithelia and 5.5 kb genome packaging capacity. Gorilla bocavirus 1 (GBoV1) VP3 shares 86% amino acid sequence identity with HB
Externí odkaz:
https://doaj.org/article/44a5004850054f418bcd4dc8d9e1ce4e
Autor:
Mario Mietzsch, Ariana Jose, Paul Chipman, Nilakshee Bhattacharya, Nadia Daneshparvar, Robert McKenna, Mavis Agbandje-McKenna
Publikováno v:
Viruses, Vol 13, Iss 1, p 101 (2021)
The capsid structures of most Adeno-associated virus (AAV) serotypes, already assigned to an antigenic clade, have been previously determined. This study reports the remaining capsid structures of AAV7, AAV11, AAV12, and AAV13 determined by cryo-elec
Externí odkaz:
https://doaj.org/article/e6fad670049f433a91ad07adeecd5a0e
Autor:
Nancy F. Ramia, Michael Spilman, Li Tang, Yaming Shao, Joshua Elmore, Caryn Hale, Alexis Cocozaki, Nilakshee Bhattacharya, Rebecca M. Terns, Michael P. Terns, Hong Li, Scott M. Stagg
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1610-1617 (2014)
Summary: The Cmr complex is the multisubunit effector complex of the type III-B clustered regularly interspaced short palindromic repeats (CRISPR)-Cas immune system. The Cmr complex recognizes a target RNA through base pairing with the integral CRISP
Externí odkaz:
https://doaj.org/article/2c5352f1fab84d3189ed7347de470f5b
Autor:
Nilakshee Bhattacharya, Ariana Jose, Jennifer C. Yu, J. Kennon Smith, Shanan N Emmanuel, Mario Mietzsch, Vibhu Banala, Mavis Agbandje-McKenna, Paul R. Chipman, Robert McKenna
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 362-373 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Affinity-based purification of adeno-associated virus (AAV) vectors has replaced density-based methods for vectors used in clinical settings. This method utilizes camelid single-domain antibodies recognizing AAV capsids. These include AVB Sepharose (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1e9858e7671d3535f990872bfb70c3
http://www.sciencedirect.com/science/article/pii/S2329050120302059
http://www.sciencedirect.com/science/article/pii/S2329050120302059
Autor:
Mario Mietzsch, Joshua A. Hull, Victoria E. Makal, Alberto Jimenez Ybargollin, Jennifer C. Yu, Kedrick McKissock, Antonette Bennett, Judit Penzes, Bridget Lins-Austin, Qian Yu, Paul Chipman, Nilakshee Bhattacharya, Duncan Sousa, David Strugatsky, Peter Tijssen, Robert McKenna, Mavis Agbandje-McKenna
Publikováno v:
J Virol
Adeno-associated viruses (AAVs) are being developed as clinical gene therapy vectors. One issue undermining their broad use in the clinical setting is the high prevalence of circulating antibodies in the general population capable of neutralizing AAV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04a8a862c9fd3f640f341b011cb7cd8
https://europepmc.org/articles/PMC9175632/
https://europepmc.org/articles/PMC9175632/
Autor:
Rick Huang, Judit J Pénzes, Mavis Agbandje-McKenna, Robert McKenna, Allison Zeher, Paul R. Chipman, Nilakshee Bhattacharya
Publikováno v:
J Virol
Adeno-associated viruses (AAVs) are small nonenveloped single-stranded DNA (ssDNA) viruses that are currently being developed as gene therapy biologics. After cell entry, AAVs traffic to the nucleus using the endo-lysosomal pathway. The subsequent de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f00dcf83bb5687c25582cca4f9e1237
https://europepmc.org/articles/PMC8428384/
https://europepmc.org/articles/PMC8428384/
Autor:
Momona Yamagami, Mavis Agbandje-McKenna, Nilakshee Bhattacharya, Duncan Sousa, Sunkuk Kwon, Junghae Suh, Caitlin M. Guenther, Eva M. Sevick-Muraca, Julie Voss, Weitong Chen, Michael T Lam, Michelle L. Ho, Antonette Bennett, Banghe Zhu, Mitchell J. Brun, Annicka C. Evans
Publikováno v:
Molecular Therapy. 27:611-622
Adeno-associated virus (AAV) has emerged as a promising gene delivery vector because of its non-pathogenicity, simple structure and genome, and low immunogenicity compared to other viruses. However, its adoption as a safe and effective delivery vecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee89f633e78eed0b84a9266b3226c1af
https://doi.org/10.1016/j.ymthe.2019.01.015
https://doi.org/10.1016/j.ymthe.2019.01.015
Autor:
Julia Fakhiri, Aurelija Žvirblienė, Indrė Kučinskaitė-Kodzė, Paul R. Chipman, Jennifer C. Yu, Alberto Jimenez Ybargollin, Mavis Agbandje-McKenna, Amriti Singh, Nilakshee Bhattacharya, Shweta Kailasan, Robert McKenna, Mario Mietzsch, Dirk Grimm, Maria Söderlund-Venermo, Amit Kapoor
Publikováno v:
Viruses
Viruses, Vol 13, Iss 330, p 330 (2021)
Volume 13
Issue 2
Viruses, Basel : MDPI, 2021, vol. 13, iss. 2, art. no. 330, p. [1-17]
Viruses, Vol 13, Iss 330, p 330 (2021)
Volume 13
Issue 2
Viruses, Basel : MDPI, 2021, vol. 13, iss. 2, art. no. 330, p. [1-17]
Human bocavirus 1 (HBoV1) has gained attention as a gene delivery vector with its ability to infect polarized human airway epithelia and 5.5 kb genome packaging capacity. Gorilla bocavirus 1 (GBoV1) shares 86% amino acid sequence identity with HBoV1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e0a93aa7713b0f188f7056aacf061d
http://hdl.handle.net/10138/329129
http://hdl.handle.net/10138/329129
Autor:
Nilakshee Bhattacharya, Paul R. Chipman, Mavis Agbandje-McKenna, Robert McKenna, Ariana Jose, Mario Mietzsch, Nadia Daneshparvar
Publikováno v:
Viruses
Viruses, Vol 13, Iss 101, p 101 (2021)
Volume 13
Issue 1
Viruses, Vol 13, Iss 101, p 101 (2021)
Volume 13
Issue 1
The capsid structures of most Adeno-associated virus (AAV) serotypes, already assigned to an antigenic clade, have been previously determined. This study reports the remaining capsid structures of AAV7, AAV11, AAV12, and AAV13 determined by cryo-elec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda76bf56248f236efd321ce5a973b27
https://pubmed.ncbi.nlm.nih.gov/33450892
https://pubmed.ncbi.nlm.nih.gov/33450892