Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Nilüfer Bayrak"'
Autor:
Ayse Tarbin Jannuzzi, Ayse Mine Yilmaz Goler, Abanish Biswas, Subodh Mondal, Vinay N. Basavanakatti, Hatice Yıldırım, Mahmut Yıldız, Nilüfer Bayrak, Venkatesan Jayaprakash, Amaç Fatih TuYuN
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1241 (2024)
The evaluation of in vitro biological activity of several previously reported quinolinequinones (AQQ1–5) against 60 human cancer cell lines (NCI-60) used by the National Cancer Institute’s Developmental Therapeutics Program (DTP) contributed to o
Externí odkaz:
https://doaj.org/article/3e5951f9dc914568955154d85a63a275
Autor:
Nilüfer Bayrak, Belgin Sever, Halilibrahim Ciftci, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 50 (2023)
The development of new anticancer drugs is still ongoing as a solution to the unsatisfactory results obtained by chemotherapy patients. Our previous studies on natural product-based anticancer agents led us to synthesize a new series of Plastoquinone
Externí odkaz:
https://doaj.org/article/4577f53f83d848ab95e92f56d64b7780
Autor:
Halilibrahim Ciftci, Belgin Sever, Nusret Kaya, Nilüfer Bayrak, Mahmut Yıldız, Hatice Yıldırım, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN
Publikováno v:
Molecules, Vol 28, Iss 1, p 77 (2022)
Colorectal cancer (CRC), breast cancer, and chronic myeloid leukemia (CML) are life-threatening malignancies worldwide. Although potent therapeutic and screening strategies have been developed so far, these cancer types are still major public health
Externí odkaz:
https://doaj.org/article/0ea0513370444aff92ed135226582c63
Publikováno v:
Antibiotics, Vol 11, Iss 10, p 1397 (2022)
Microorganisms are responsible for hospital infections, and methicillin-resistant Staphylococcus aureus is one of them. In looking for the most effective lead structures to cope with the rise of antimicrobial (antibiotic) resistance, we evaluated the
Externí odkaz:
https://doaj.org/article/176ccb5945c24cd8ab07b01fe32fee11
Autor:
Halilibrahim Ciftci, Belgin Sever, Nilüfer Bayrak, Mahmut Yıldız, Hatice Yıldırım, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1266 (2022)
Colorectal cancer (CRC) and breast cancer are leading causes of death globally, due to significant challenges in detection and management. The late-stage diagnosis and treatment failures require the discovery of potential anticancer agents to achieve
Externí odkaz:
https://doaj.org/article/2163f81d14724c4ba2ba6d721b438be3
Autor:
Ayse Tarbin Jannuzzi, Ayse Mine Yilmaz Goler, Nilüfer Bayrak, Mahmut Yıldız, Hatice Yıldırım, Betul Karademir Yilmaz, Deepak Shilkar, Raghusrinivasan Jayaprakash Venkatesan, Venkatesan Jayaprakash, Amaç Fatih TuYuN
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 777 (2022)
Plastoquinone analogs are privileged structures among the known antiproliferative natural product-based compound families. Exploiting one of these analogs as a lead structure, we report the investigation of the brominated PQ analogs (BrPQ) in collabo
Externí odkaz:
https://doaj.org/article/a9c5bcc818f548319639bd28c324120f
Autor:
Hatice Yıldırım, Mahmut Yıldız, Nilüfer Bayrak, Emel Mataracı-Kara, Mohamed Osman Radwan, Ayse Tarbin Jannuzzi, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 586 (2022)
In the present study, we designed and synthesized thiolated VK3 analogs (VK3a–g) along with an extensive antimicrobial study. After the evaluation of the antibacterial and antifungal activity against various bacterial and fungal strains, we present
Externí odkaz:
https://doaj.org/article/f0ee5dd5c886417e906972626573682d
Autor:
Hatice Yıldırım, Nilüfer Bayrak, Mahmut Yıldız, Fatıma Nur Yılmaz, Emel Mataracı-Kara, Deepak Shilkar, Venkatesan Jayaprakash, Amaç Fatih TuYuN
Publikováno v:
Molecules, Vol 27, Iss 9, p 2923 (2022)
Two subseries of aminated quinolinequinones (AQQs, AQQ1–16) containing electron-withdrawing group (EWG) or electron-donating group (EDG) in aryl amine moiety were successfully synthesized. Antimicrobial activity assessment indicates that some of th
Externí odkaz:
https://doaj.org/article/1e1dae92a0dc47e4a340e8e04f37195d
Autor:
Halilibrahim Ciftci, Belgin Sever, Firdevs Ocak, Nilüfer Bayrak, Mahmut Yıldız, Hatice Yıldırım, Hasan DeMirci, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN
Publikováno v:
Molecules, Vol 27, Iss 3, p 693 (2022)
Plants have paved the way for the attainment of molecules with a wide-range of biological activities. However, plant products occasionally show low biological activities and/or poor pharmacokinetic properties. In that case, development of their deriv
Externí odkaz:
https://doaj.org/article/fbd69e78f95b4f9cb9c77ce8e8a04c5d
Autor:
Amaç Fatih Tuyun, Nilüfer Bayrak, Hatice Yıldırım, Nihal Onul, Emel Mataraci Kara, Berna Ozbek Celik
Publikováno v:
Journal of Chemistry, Vol 2015 (2015)
A series of 2-arylamino-3-chloro-1,4-naphthoquinone derivatives (3a–h) by the reaction of 2,3-dichloro-1,4-naphthoquinone with aryl amines (2a–h) and benzo[b]phenazine-6,11-dione derivatives (4a–c) by the treatment of 2-arylamino-3-chloro-1,4-n
Externí odkaz:
https://doaj.org/article/649a935b45f54177a43f0b4ae1ba3a1f