Výsledky vyhledávání - "Nikunj Mapara"

Self-Assembled Oleic Acid Nanoparticle Mediated Inhibition of Mitogen-Activated Protein Kinase Signaling in Combination with DNA Damage in Cancer Cells

Autor: Jyothi Nagraj, Nikunj Mapara, Rajdeep Chowdhury, Sudipta Basu, Sandeep Palvai, Piyush More

Publikováno v: ChemNanoMat. 2:201-211

Mitogen-activated protein kinase (MAPK) signaling has been dysregulated in different types of cancers. However, targeting MAPK signaling with small molecules leads to severe toxic side effects to the patients as well as manifestation of drug resistan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7fc975a099f07fc3e68a7823c1301c6
https://doi.org/10.1002/cnma.201500195

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Chimeric Nanoparticle: A Platform for Simultaneous Targeting of Phosphatidylinositol-3-Kinase Signaling and Damaging DNA in Cancer Cells

Autor: Sandeep Palvai, Sudipta Basu, Nikunj Mapara, Piyush More

Publikováno v: ACS Applied Materials & Interfaces. 7:18327-18335

Phosphatidylinositol-3-kinase (PI3K) signaling has been hijacked in different types of cancers. Hence, PI3K inhibitors have emerged as novel targeted therapeutics in cancer treatment as mono and combination therapy along with other DNA damaging drugs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786fa15526c516b0c18b8888852cd5e2
https://doi.org/10.1021/acsami.5b04015

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Dual drug loaded vitamin D3 nanoparticle to target drug resistance in cancer

Autor: Nikunj Mapara, Sandeep Palvai, Rajdeep Chowdhury, Sudipta Basu, Jyothi Nagraj

Publikováno v: RSC Adv.. 4:57271-57281

Overcoming drug resistance is one of the most challenging problems in cancer chemotherapy. Drug cocktails can overcome the drug resistance. However, multiple drug combinations lead to multifold increment of off-target toxicity, as well as the deliver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dda2ce62162683cc8835ab8873db6705
https://doi.org/10.1039/c4ra06475e

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Antimicrobial potentials of Helicteres isora silver nanoparticles against extensively drug-resistant (XDR) clinical isolates of Pseudomonas aeruginosa

Autor: Renu Bharadwaj, Kakasaheb C. Mohite, Mansi Sharma, Varsha Shriram, Vinay Kumar, Nikunj Mapara

Publikováno v: Applied microbiology and biotechnology. 99(24)

Pseudomonas aeruginosa is a leading opportunistic pathogen and its expanding drug resistance is a growing menace to public health. Its ubiquitous nature and multiple resistance mechanisms make it a difficult target for antimicrobial chemotherapy and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dad993f89c1dea079cf8e9ba7fa819a
https://pubmed.ncbi.nlm.nih.gov/26362684

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