Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties.

Autor: Hudson AR; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States. Electronic address: andyrhudson@gmail.com., Santora VJ; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Petroski RE; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Almos TA; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Anderson G; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Barido R; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Basinger J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Bellows CL; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Bookser BC; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Broadbent NJ; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Cabebe C; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Chai CK; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Chen M; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Chow S; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Chung M; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Heger L; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Danks AM; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Freestone GC; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Gitnick D; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Gupta V; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Hoffmaster C; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Kaplan AP; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Kennedy MR; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Lee D; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Limberis J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Ly K; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Mak CC; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Masatsugu B; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Morse AC; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Na J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Neul D; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Nikpur J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Renick J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Sebring K; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Sevidal S; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Tabatabaei A; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Wen J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Xia S; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Yan Y; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Yoder ZW; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Zook D; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Peters M; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Breitenbucher JG; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Jul 15; Vol. 30 (14), pp. 127214. Date of Electronic Publication: 2020 Apr 25.

Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties.

Autor: Santora VJ; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Almos TA; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Barido R; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Basinger J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Bellows CL; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Bookser BC; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Breitenbucher JG; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Broadbent NJ; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Cabebe C; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Chai CK; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Chen M; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Chow S; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Chung M; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Crickard L; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Danks AM; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Freestone GC; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Gitnick D; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Gupta V; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Hoffmaster C; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Hudson AR; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Kaplan AP; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Kennedy MR; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Lee D; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Limberis J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Ly K; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Mak CC; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Masatsugu B; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Morse AC; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Na J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Neul D; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Nikpur J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Peters M; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Petroski RE; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Renick J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Sebring K; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Sevidal S; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Tabatabaei A; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Wen J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Yan Y; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Yoder ZW; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Zook D; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2018 Jul 26; Vol. 61 (14), pp. 6018-6033. Date of Electronic Publication: 2018 Jul 11.

Reaction of 1‐Phenacylidene pyrrolo[3,2,1‐ij]quinolin‐2‐ones with Cyclic/Acyclic Enaminones and the Anticoagulant Activity of Synthesized Pyrrole‐Quinoline Derivatives.

Autor: Skoptsova, Anna A.¹ (AUTHOR), Shestakov, Alexander S.¹ (AUTHOR), Ledenyova, Irina V.¹ (AUTHOR), Stolpovskaya, Nadezhda V.¹ (AUTHOR), Podoplelova, Nadezhda A.² (AUTHOR), Panteleev, Mikhail A.² (AUTHOR), Paponov, Boris V.³ (AUTHOR), Sidorenko, Oleg E.¹ (AUTHOR), Shikhaliev, Khidmet S.¹ (AUTHOR), Novichikhina, Nadezhda P.¹ (AUTHOR) novichikhina@chem.vsu.ru

Publikováno v: ChemistrySelect. 12/13/2022, Vol. 7 Issue 46, p1-8. 8p.

Conditioning processes contribute to severity of naloxone-precipitated withdrawal from acute opioid dependence.

Autor: Schulteis, Gery¹ gschulteis@vapop.ucsd.edu, Morse, Andrew C.^1,2,3, Jian Liu¹

Publikováno v: Psychopharmacology. 2004, Vol. 175 Issue 4, p463-472. 10p. 1 Chart, 4 Graphs.

Applications of Heterocycles in the Design of Drugs and Agricultural Products

Autor: Nicholas A. Meanwell, Marco L. Lolli

Applications of Heterocycles in the Design of Drugs and Agricultural Products, Volume 134 in the Advances in Heterocyclic Chemistry series represents the most definitive series in the field - one of great importance to organic chemists, polymer chemi