Transforming the prostatic tumor microenvironment with oncolytic virotherapy.

Autor: Atherton MJ; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada., Stephenson KB; Turnstone Biologics, Ottawa, Canada., Tzelepis F; Centre for Cancer Therapeutics, The Ottawa Hospital Research Institute, Ottawa, Canada., Bakhshinyan D; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, Canada.; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, Canada., Nikota JK; Turnstone Biologics, Ottawa, Canada., Son HH; Centre for Cancer Therapeutics, The Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Canada., Jirovec A; Centre for Cancer Therapeutics, The Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Canada., Lefebvre C; Stojdl Lab, CHEO Research Institute, Children's Hospital of Eastern Ontario, Ottawa, Canada., Dvorkin-Gheva A; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada., Ashkar AA; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada., Wan Y; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada., Stojdl DF; Turnstone Biologics, Ottawa, Canada.; Stojdl Lab, CHEO Research Institute, Children's Hospital of Eastern Ontario, Ottawa, Canada., Belanger EC; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada., Breau RH; Department of Surgery, The Ottawa Hospital, Ottawa, Canada., Bell JC; Turnstone Biologics, Ottawa, Canada.; Centre for Cancer Therapeutics, The Ottawa Hospital Research Institute, Ottawa, Canada., Saad F; Department of Surgery, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Canada., Singh SK; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, Canada.; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, Canada.; Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, Canada.; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Canada., Diallo JS; Centre for Cancer Therapeutics, The Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Canada., Lichty BD; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada.; Turnstone Biologics, Ottawa, Canada.

Publikováno v: Oncoimmunology [Oncoimmunology] 2018 Mar 27; Vol. 7 (7), pp. e1445459. Date of Electronic Publication: 2018 Mar 27 (Print Publication: 2018).

Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice.

Autor: Shen P; Medical Sciences Graduate Program, McMaster University, Hamilton, Ontario, Canada., Morissette MC; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada., Vanderstocken G; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada., Gao Y; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada., Hassan M; Honours Biology and Pharmacology Co-op Program, McMaster University, Hamilton, Ontario, Canada., Roos A; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada.; Department of Experimental Medical Science, Lund University, Lund, Sweden., Thayaparan D; Honours Molecular Biology and Genetics Co-op Program, McMaster University, Hamilton, Ontario, Canada., Merlano M; Honours Bachelor of Health Sciences Undergraduate Program, McMaster University, Hamilton, Ontario, Canada., Dorrington MG; Medical Sciences Graduate Program, McMaster University, Hamilton, Ontario, Canada., Nikota JK; Medical Sciences Graduate Program, McMaster University, Hamilton, Ontario, Canada., Bauer CMT; Hoffmann-La Roche, pRED, Pharma Research and Early Development, DTA Inflammation, Nutley, New Jersey, USA., Kwiecien JM; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Neurosurgery and Paediatric Neurosurgery, Medical University of Lublin, Lublin, Poland., Labiris R; Department of Medicine, Division of Respirology, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, Firestone Institute for Respiratory Health at St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada., Bowdish DME; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada., Stevenson CS; Hoffmann-La Roche, pRED, Pharma Research and Early Development, DTA Inflammation, Nutley, New Jersey, USA., Stämpfli MR; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada stampfli@mcmaster.ca.; Department of Medicine, Firestone Institute for Respiratory Health at St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada.

Publikováno v: Infection and immunity [Infect Immun] 2016 Apr 22; Vol. 84 (5), pp. 1536-1547. Date of Electronic Publication: 2016 Apr 22 (Print Publication: 2016).

Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in mice.

Autor: Nikota JK; Medical Sciences Graduate Program, McMaster University, Hamilton, Ontario L8S 4K1, Canada;, Shen P; Medical Sciences Graduate Program, McMaster University, Hamilton, Ontario L8S 4K1, Canada;, Morissette MC; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario L8S 4K1, Canada;, Fernandes K; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario L8S 4K1, Canada;, Roos A; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario L8S 4K1, Canada;, Chu DK; Medical Sciences Graduate Program, McMaster University, Hamilton, Ontario L8S 4K1, Canada;, Barra NG; Medical Sciences Graduate Program, McMaster University, Hamilton, Ontario L8S 4K1, Canada;, Iwakura Y; Center for Experimental Medicine and Systems Biology, Institute of Medical Science, University of Tokyo, Tokyo 113-8654, Japan;, Kolbeck R; MedImmune LLC, Gaithersburg, MD 20878; and., Humbles AA; MedImmune LLC, Gaithersburg, MD 20878; and., Stampfli MR; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario L8S 4K1, Canada; Department of Medicine, Firestone Institute for Respiratory Health at St. Joseph's Healthcare, McMaster University, Hamilton, Ontario L8N 4A6, Canada.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2014 Sep 15; Vol. 193 (6), pp. 3134-45. Date of Electronic Publication: 2014 Aug 04.

Alterations in skeletal muscle cell homeostasis in a mouse model of cigarette smoke exposure.

Autor: Caron MA; Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Québec, and Laval University, Quebec City, Quebec, Canada., Morissette MC, Thériault ME, Nikota JK, Stämpfli MR, Debigaré R

Publikováno v: PloS one [PLoS One] 2013 Jun 14; Vol. 8 (6), pp. e66433. Date of Electronic Publication: 2013 Jun 14 (Print Publication: 2013).

Cigarette smoke-induced inflammation and respiratory host defense: Insights from animal models.

Autor: Nikota JK; Medical Sciences Graduate Program, McMaster University, Hamilton, Canada., Stämpfli MR

Publikováno v: Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2012 Aug; Vol. 25 (4), pp. 257-62. Date of Electronic Publication: 2012 May 24.