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pro vyhledávání: '"Nikos Papalexis"'
Publikováno v:
When Things Go Wrong-Diseases and Disorders of the Human Brain
Since its discovery in the PC12 rat pheochromocytoma cell line (Montminy & Bilezikjian 1987) the cAMP Response Element Binding (CREB) protein has been implicated in a variety of neuronal responses such as excitation, long-term memory formation, neura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b85aa6ee97229bbba78e4aea3691c9
http://www.intechopen.com/articles/show/title/creb-signaling-in-neural-stem-progenitor-cells-implications-for-a-role-in-brain-tumors
http://www.intechopen.com/articles/show/title/creb-signaling-in-neural-stem-progenitor-cells-implications-for-a-role-in-brain-tumors
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 34(4)
This paper discusses the evidence for the role of CREB in neural stem/progenitor cell (NSPC) function and oncogenesis and how these functions may be important for the development and growth of brain tumours. The cyclic-AMP response element binding (C
Autor:
Giovanna M. D'Abaco, Nikos Papalexis, Paul M. Daniel, Daniel Brown, Robert G. Ramsay, Frédéric Hollande, Gulay Filiz, Theo Mantamadiotis, Wayne A. Phillips, Jordane Malaterre, Michael Gonzales
Publikováno v:
Oncogenesis
The cyclic-AMP response element binding (CREB) protein has been shown to have a pivotal role in cell survival and cell proliferation. Transgenic rodent models have revealed a role for CREB in higher-order brain functions, such as memory and drug addi