Identification of risk loci with shared effects on five major psychiatric disorders:a genome-wide analysis

Autor: Smoller, J.W., Ripke, S., Lee, P.H., Neale, B., Nurnberger, J.I., Santangelo, S., Sullivan, P.F., Perlis, R.H., Purcell, S.M., Fanous, A., Neale, M.C., Rietschel, M., Schulze, T.G., Thapar, A., Anney, R., Buitelaar, J.K., Farone, S.V., Hoogendijk, W.J.G., Levinson, D.F., Lesch, K.P., Riley, B., Schachar, R., Sonuga-Barke, E.J., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O.A., Anjorin, A., Arking, D., Asherson, P., Azevedo, M.H., Backlund, L., Badner, J.A., Banaschewski, T., Barchas, J.D., Barnes, M.R., Bass, N., Bauer, M.C.R., Bellivier, F., Bergen, S.E., Berrettini, W., Bettecken, T., Biederman, J, Binder, E.B., Black, D.W., Blackwood, D.H., Bloss, C.S., Boehnke, M., Boomsma, D.I., Breen, G., Breuer, R., Buccola, N.G., Bunner, W.E., Burmeister, M., Buxbaum, J.D., Byerley, W. F., Sian, C., Cantor, R.M., Chakravarti, A., Chambert, K., Chicon, S., Cloniger, C.R., Collier, D.A., Cook, E., Coon, H., Corvin, A., Coryell, W.H., Craig, D.W., Craig, I.W., Curtis, D., Czamara, D., Daly, M., Datta, S., Day, R., de Geus, E.J.C., Degenhardt, F., Devlin, B., Srdjan, D., Doyle, A.E., Duan, J., Dudbridge, F., Edenberg, H.J., Elkin, A., Etain, B., Farmer, A.E., Ferreira, M.A.R., Ferrier, I.N., Flickinger, M., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N.B., Friedl, M., Frisén, L., Gejman, P.V., Georgieva, L., Gershon, E.S., Giegling, I., Gill, M., Gordon, S.D., Gordon-Smith, K., Green, E.K., Greenwood, T.A., Gross, M., Grozeva, D., Guan, W., Gurling, H., Gustafsson, O., Hakonarson, H., Hamilton, S.P., Hamshere, M.L., Hansen, T.F., Hartmann, A.M., Hautzinger, M., Heath, A.C., Henders, A.K., Herms, S., Hickie, I.B., Hipolito, M., Hoefels, S., Holmans, P.A., Holsboer, F., Hottenga, J.J., Hultman, C. M., Ingason, A., Ising, M., Jamain, S., Jones, E.G., Jones, L., Jones, I., Jung-Ying, T., Kahler, A., Kandaswamy, R., Keller, M.C., Kelsoe, J., Kennedy, J.L., Kenny, E., Kim, Y., Kirov, G. K., Knowles, J.A., Kohli, M.A., Koller, D.L., Konte, B., Korszun, A., Krasucki, R., Kuntsi, J., Phoenix, K., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W.B., Leboyer, M., Lencz, T., Lewis, C.M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D., Liu, C., Lohoff, F.W., Loo, S.K., Lucae, S., MacIntyre, D.J., Madden, P.A.F., Magnusson, P., Mahon, P.B., Maier, W., Malhotra, A.K., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S., McGhee, K.A., McGough, J.J., McGrath, P.J., McGuffin, P., McInnis, M.G., McIntosh, A., McKinney, R., McClean, A.W., McMahon, F.J., McQuillin, A., Medeiros, H., Medland, S.E., Meier, S., Melle, I., Meng, F., Middeldorp, C.M., Middleton, L., Vihra, M., Mitchell, P.B., Montgomery, G.W., Moran, J., Morken, G., Morris, D.W., Moskvina, V., Mowry, B. J., Muglia, P., Mühleisen, T.W., Muir, W.J., Müller-Myhsok, B., Myers, R.M., Nelson, S.F., Nievergelt, C.M., Nikolovq, I., Nimgaonkar, V.L., Nolen, W.A., Nöthen, M.M., Nwulia, E.A., Nyholt, DR, O'Donovan, M.C., O'Dushlaine, C., Oades, R.D., Olincy, A., Olsen, L., Ophoff, R.A., Osby, U., Óskarsson, H., Owen, M.J., Palotie, A., Pato, M.T., Pato, C.N., Penninx, B.W.J.H., Pergadia, M.L., Petursson, H., Pickard, B.S., Pimm, J., Piven, J., Porgeirsson, P., Posthuma, D., Potash, J.B., Propping, J., Puri, V., Quested, D., Quinn, E.M., Rasmussen, H.B., Raychaudhuri, S., Rehnström, K., Reif, A., Rice, J., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A.R., Schalling, M., Schatzberg, A.F., Scheftner, W.A., Schellenberg, G.D., Schofield, P.R., Schork, N.J., Schumacher, J., Schwarz, M.M., Scolnick, E., Scott, L.J., Shi, J., Shillling, P.D., Shyn, S.I., Sigurdsson, E., Silverman, J.M., Sklar, P., Slager, S.L., Smalley, S.L., Smit, J.H., Smith, E.N., Sonuga-Barke, E., St Clair, D., State, M., Stefansson, K., Stefansson, H., Steffans, M., Steinberg, S., Steinhausen, H.C., Strauss, J., Strohmaier, J., Stroup, T.S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R.C., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E.J., Grootheest, G., Vieland, V., Vincent, J.B., Visscher, P.M., Watson, S.J., Weissman, M.M., Werge, T., Wienker, T.F., Willemsen, G., Williamson, R., Witt, S.H., Wray, N.R., Wright, A., Xu, W., Young, A.H., Zammit, S., Zandi, P.P., Zhang, P., Zitman, F.G., Zöllner, S., Kendler, K.S.

Publikováno v: Cross-Disorder Group of the Psychiatric Genomics Consortium 2013, ' Identification of risk loci with shared effects on five major psychiatric disorders : a genome-wide analysis ', Lancet, vol. 381, no. 9875, pp. 1371-9 . https://doi.org/10.1016/S0140-6736(12)62129-1
The Lancet (London), 381, 1371-9
Lancet, 381(9875), 1371-1379. Elsevier Limited
Smoller, J W, Ripke, S, Lee, P H, Neale, B, Nurnberger, J I, Santangelo, S, Sullivan, P F, Perlis, R H, Purcell, S M, Fanous, A, Neale, M C, Rietschel, M, Schulze, T G, Thapar, A, Anney, R, Buitelaar, J K, Farone, S V, Hoogendijk, W J G, Levinson, D F, Lesch, K P, Riley, B, Schachar, R, Sonuga-Barke, E J, Absher, D, Agartz, I, Akil, H, Amin, F, Andreassen, O A, Anjorin, A, Arking, D, Asherson, P, Azevedo, M H, Backlund, L, Badner, J A, Banaschewski, T, Barchas, J D, Barnes, M R, Bass, N, Bauer, M C R, Bellivier, F, Bergen, S E, Berrettini, W, Bettecken, T, Biederman, J, Binder, E B, Black, D W, Blackwood, D H, Bloss, C S, Boehnke, M, Boomsma, D I, Breen, G, Breuer, R, Buccola, N G, Bunner, W E, Burmeister, M, Buxbaum, J D, Byerley, W F, Sian, C, Cantor, R M, Chakravarti, A, Chambert, K, Chicon, S, Cloniger, C R, Collier, D A, Cook, E, Coon, H, Corvin, A, Coryell, W H, Craig, D W, Craig, I W, Curtis, D, Czamara, D, Daly, M, Datta, S, Day, R, de Geus, E J C, Degenhardt, F, Devlin, B, Srdjan, D, Doyle, A E, Duan, J, Dudbridge, F, Edenberg, H J, Elkin, A, Etain, B, Farmer, A E, Ferreira, M A R, Ferrier, I N, Flickinger, M, Foroud, T, Frank, J, Franke, B, Fraser, C, Freedman, R, Freimer, N B, Friedl, M, Frisén, L, Gejman, P V, Georgieva, L, Gershon, E S, Giegling, I, Gill, M, Gordon, S D, Gordon-Smith, K, Green, E K, Greenwood, T A, Gross, M, Grozeva, D, Guan, W, Gurling, H, Gustafsson, O, Hakonarson, H, Hamilton, S P, Hamshere, M L, Hansen, T F, Hartmann, A M, Hautzinger, M, Heath, A C, Henders, A K, Herms, S, Hickie, I B, Hipolito, M, Hoefels, S, Holmans, P A, Holsboer, F, Hottenga, J J, Hultman, C M, Ingason, A, Ising, M, Jamain, S, Jones, E G, Jones, L, Jones, I, Jung-Ying, T, Kahler, A, Kandaswamy, R, Keller, M C, Kelsoe, J, Kennedy, J L, Kenny, E, Kim, Y, Kirov, G K, Knowles, J A, Kohli, M A, Koller, D L, Konte, B, Korszun, A, Krasucki, R, Kuntsi, J, Phoenix, K, Landén, M, Langstrom, N, Lathrop, M, Lawrence, J, Lawson, W B, Leboyer, M, Lencz, T, Lewis, C M, Li, J, Lichtenstein, P, Lieberman, J A, Lin, D, Liu, C, Lohoff, F W, Loo, S K, Lucae, S, MacIntyre, D J, Madden, P A F, Magnusson, P, Mahon, P B, Maier, W, Malhotra, A K, Mattheisen, M, Matthews, K, Mattingsdal, M, McCarroll, S, McGhee, K A, McGough, J J, McGrath, P J, McGuffin, P, McInnis, M G, McIntosh, A, McKinney, R, McClean, A W, McMahon, F J, McQuillin, A, Medeiros, H, Medland, S E, Meier, S, Melle, I, Meng, F, Middeldorp, C M, Middleton, L, Vihra, M, Mitchell, P B, Montgomery, G W, Moran, J, Morken, G, Morris, D W, Moskvina, V, Mowry, B J, Muglia, P, Mühleisen, T W, Muir, W J, Müller-Myhsok, B, Myers, R M, Nelson, S F, Nievergelt, C M, Nikolovq, I, Nimgaonkar, V L, Nolen, W A, Nöthen, M M, Nwulia, E A, Nyholt, DR, O'Donovan, M C, O'Dushlaine, C, Oades, R D, Olincy, A, Olsen, L, Ophoff, R A, Osby, U, Óskarsson, H, Owen, M J, Palotie, A, Pato, M T, Pato, C N, Penninx, B W J H, Pergadia, M L, Petursson, H, Pickard, B S, Pimm, J, Piven, J, Porgeirsson, P, Posthuma, D, Potash, J B, Propping, J, Puri, V, Quested, D, Quinn, E M, Rasmussen, H B, Raychaudhuri, S, Rehnström, K, Reif, A, Rice, J, Rossin, L, Rothenberger, A, Rouleau, G, Ruderfer, D, Rujescu, D, Sanders, A R, Schalling, M, Schatzberg, A F, Scheftner, W A, Schellenberg, G D, Schofield, P R, Schork, N J, Schumacher, J, Schwarz, M M, Scolnick, E, Scott, L J, Shi, J, Shillling, P D, Shyn, S I, Sigurdsson, E, Silverman, J M, Sklar, P, Slager, S L, Smalley, S L, Smit, J H, Smith, E N, Sonuga-Barke, E, St Clair, D, State, M, Stefansson, K, Stefansson, H, Steffans, M, Steinberg, S, Steinhausen, H C, Strauss, J, Strohmaier, J, Stroup, T S, Sutcliffe, J, Szatmari, P, Szelinger, S, Thirumalai, S, Thompson, R C, Tozzi, F, Treutlein, J, Uhr, M, van den Oord, E J, Grootheest, G, Vieland, V, Vincent, J B, Visscher, P M, Watson, S J, Weissman, M M, Werge, T, Wienker, T F, Willemsen, G, Williamson, R, Witt, S H, Wray, N R, Wright, A, Xu, W, Young, A H, Zammit, S, Zandi, P P, Zhang, P, Zitman, F G, Zöllner, S & Kendler, K S 2013, ' Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis ', Lancet, vol. 381, no. 9875, pp. 1371-1379 . https://doi.org/10.1016/S0140-6736(12)62129-1
Lancet, 381(9875), 1371-1379. Elsevier Science
The Lancet (London), 381, 9875, pp. 1371-9

Item does not contain fulltext BACKGROUND: Findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specific variants underlying g

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