Zobrazeno 1 - 3
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pro vyhledávání: '"Nikolina Prtenjaca"'
Autor:
Nikolina Prtenjaca, Matea Rob, Muhammad S. Alam, Andrea Markovinovic, Cristiana Stuani, Emanuele Buratti, Ivana Munitic
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6829 (2022)
Mutations in optineurin, a ubiquitin-binding adaptor protein, cause amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease of motor neurons linked to chronic inflammation and protein aggregation. The majority of ALS patients, includin
Externí odkaz:
https://doaj.org/article/6a1832d3947d402ea9603aa034434013
Autor:
Marin Dominovic, Josip Peradinovic, Rozalija Šajn, Ivana Munitic, Andrea Markovinovic, Nikolina Prtenjaca
Publikováno v:
Periodicum biologorum
Volume 121-122
Issue 1-2
Volume 121-122
Issue 1-2
Mutations in optineurin have been linked to amyotrophic lateral sclero- sis (ALS) a decade ago, but its exact role in the neurodegenerative process is still unclear. As a lysine 63 (K63)- and methionine (M1)-linked polyubiq- uitin-binding protein, op
Publikováno v:
The Journal of Immunology. 206:52.22-52.22
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease marked by protein aggregation and neuroinflammation. Protein aggregates in >95% of ALS cases are cytoplasmic and contain ubiquitinated and phosphorylated TAR DNA binding protein 43 kD