Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Nikolina Papac"'
Autor:
Mathilde Meyenberg, Anna Hakobyan, Nikolina Papac-Milicevic, Laura Göderle, Franziska L. Langner, Mateo Markovic, Ji-Hyun Lee, Bon-Kyoung Koo, Georg A. Busslinger, Israel Tojal da Silva, Christoph J. Binder, Jörg Menche, Joanna I. Loizou
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Obesity is a modifiable risk factor in cancer development, especially for gastrointestinal cancer. While the etiology of colorectal cancer is well characterized by the adenoma-carcinoma sequence, it remains unclear how obesity influences col
Externí odkaz:
https://doaj.org/article/05d48a159fbb40c28d4a3ee121140e64
Autor:
Damien Bierschenk, Nikolina Papac-Milicevic, Ian P. Bresch, Valentina Kovacic, Serena Bettoni, Mateusz Dziedzic, Rick A. Wetsel, Susanne Eschenburg, Christoph J. Binder, Anna M. Blom, Ben C. King
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Dysregulated NLRP3 inflammasome activation drives a wide variety of diseases, while endogenous inhibition of this pathway is poorly characterised. The serum protein C4b-binding protein (C4BP) is a well-established inhibitor of complement with emergin
Externí odkaz:
https://doaj.org/article/99cd06018276418c8529742dbe8a4176
Autor:
Sarah Irmscher, Svante L. H. Zipfel, Luke D. Halder, Lia Ivanov, Andres Gonzalez-Delgado, Christoph Waldeyer, Moritz Seiffert, Fabian J. Brunner, Monika von der Heide, Ina Löschmann, Sonia Wulf, Darina Czamara, Nikolina Papac-Milicevic, Olaf Strauß, Stefan Lorkowski, Hermann Reichenspurner, Michael V. Holers, Nirmal K. Banda, Tania Zeller, Elisabeth B. Binder, Christoph J. Binder, Thorsten Wiech, Peter F. Zipfel, Christine Skerka
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Atherosclerotic cardiovascular disease (ACVD) is a lipid-driven inflammatory disease and one of the leading causes of death worldwide. Lipid deposits in the arterial wall lead to the formation of plaques that involve lipid oxidation, cellula
Externí odkaz:
https://doaj.org/article/f4fef222f3624b56b6f873bb7fc7bb7a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cellular death, aging, and tissue damage trigger inflammation that leads to enzymatic and non-enzymatic lipid peroxidation of polyunsaturated fatty acids present on cellular membranes and lipoproteins. This results in the generation of highly reactiv
Externí odkaz:
https://doaj.org/article/16c208496ab3477f91a3af6f1b0ea2cb
Autor:
Máté G. Kiss, Mária Ozsvár-Kozma, Florentina Porsch, Laura Göderle, Nikolina Papac-Miličević, Barbara Bartolini-Gritti, Dimitrios Tsiantoulas, Matthew C. Pickering, Christoph J. Binder
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Complement factor H (CFH) has a pivotal role in regulating alternative complement activation through its ability to inhibit the cleavage of the central complement component C3, which links innate and humoral immunity. However, insights into the role
Externí odkaz:
https://doaj.org/article/25e4cad9ee3249c3b30102ef7b31604f
Autor:
Dimitrios Tsiantoulas, Thomas Perkmann, Taras Afonyushkin, Andreas Mangold, Thomas A. Prohaska, Nikolina Papac-Milicevic, Vincent Millischer, Caroline Bartel, Sohvi Hörkkö, Chantal M. Boulanger, Sotirios Tsimikas, Michael B. Fischer, Joseph L. Witztum, Irene M. Lang, Christoph J. Binder
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 440-448 (2015)
Oxidation-specific epitopes (OSEs) present on apoptotic cells and oxidized low density lipoprotein (OxLDL) represent danger-associated molecular patterns that are recognized by different arcs of innate immunity, including natural IgM antibodies. Here
Externí odkaz:
https://doaj.org/article/3716a646b8944c4283de81d5bdef220c
Autor:
Larissa Cardilo‐Reis, Sabrina Gruber, Sabine M. Schreier, Maik Drechsler, Nikolina Papac‐Milicevic, Christian Weber, Oswald Wagner, Herbert Stangl, Oliver Soehnlein, Christoph J. Binder
Publikováno v:
EMBO Molecular Medicine, Vol 4, Iss 10, Pp 1072-1086 (2012)
Abstract Atherosclerotic lesions are characterized by the accumulation of oxidized LDL (OxLDL) and the infiltration of macrophages and T cells. Cytokine expression in the microenvironment of evolving lesions can profoundly contribute to plaque develo
Externí odkaz:
https://doaj.org/article/27e9db6fa6f848059c7ae41fbd6fc517
Autor:
Tim Hendrikx, Florentina Porsch, Máté G. Kiss, Dragana Rajcic, Nikolina Papac-Miličević, Constanze Hoebinger, Laura Goederle, Anastasiya Hladik, Lisa E. Shaw, Hauke Horstmann, Sylvia Knapp, Sophia Derdak, Martin Bilban, Lena Heintz, Marcin Krawczyk, Rafael Paternostro, Michael Trauner, Matthias Farlik, Dennis Wolf, Christoph J. Binder
Publikováno v:
Journal of Hepatology, 77(5), 1373-1385. Elsevier Science
BACKGROUND & AIMS: Previous single-cell RNA-sequencing analyses have shown that Trem2-expressing macrophages are present in the liver during obesity, non-alcoholic steatohepatitis (NASH) and cirrhosis. Herein, we aimed to functionally characterize th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc35e9ab4202dfa69601804f0eecf88
https://doi.org/10.1016/j.jhep.2022.06.004
https://doi.org/10.1016/j.jhep.2022.06.004
Autor:
M. Leontien van der Bent, Hailiang Mei, Reinier A. Boon, Daphne A L van den Homberg, Paul H.A. Quax, Johann Wojta, Veerle Kremer, Nikolina Papac-Milicevic, A. Yaël Nossent, Eva van Ingen
Publikováno v:
van Ingen, E, van den Homberg, D A L, van der Bent, M L, Mei, H, Papac-Milicevic, N, Kremer, V, Boon, R A, Quax, P H A, Wojta, J & Nossent, A Y 2022, ' C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation ', Human Molecular Genetics, vol. 31, no. 7, pp. 1051-1066 . https://doi.org/10.1093/hmg/ddab304
Human Molecular Genetics, 31(7), 1051-1066. OXFORD UNIV PRESS
Human Molecular Genetics, 31(7), 1051-1066. Oxford University Press
Human Molecular Genetics, 31(7), 1051-1066. OXFORD UNIV PRESS
Human Molecular Genetics, 31(7), 1051-1066. Oxford University Press
We have previously shown that C/D box small nucleolar RNAs (snoRNAs) transcribed from the DLK1-DIO3 locus on human chromosome 14 (14q32) are associated with cardiovascular disease. DLK1-DIO3 snoRNAs are ‘orphan snoRNAs’ that have no known targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b58e08eb44713352dff1899c53be85
https://research.vumc.nl/en/publications/6e40b26c-732c-409a-ae7e-ad9a7fce5582
https://research.vumc.nl/en/publications/6e40b26c-732c-409a-ae7e-ad9a7fce5582
Autor:
Christoph J. Binder, Maria Ozsvar-Kozma, Nikolina Papac-Milicevic, Elisabeth B. Binder, Gregor Hoermann, Darina Czamara, Christine Skerka, Lejla Alic, Stefanie Haslinger-Hutter, Andrea Hartmann, Ramona B. Rudnick, Michael Gurbisz, Peter F. Zipfel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Dysregulation of the alternative complement pathway due to impaired binding of complement factor H (CFH) to self-ligands or altered self-ligands (e.g. malondialdehyde [MDA]-modified molecules) involved in homeostasis can promote the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c560779ec92f8d732161f8b3715629
http://europepmc.org/articles/PMC7211993
http://europepmc.org/articles/PMC7211993