Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Nikolina Mihaylova"'
Design, Development and Immunogenicity Study of a Multi-Epitope Vaccine Prototype Against SARS-CoV-2
Autor:
Mariyana Atanasova, Ivan Dimitrov, Nikola Ralchev, Aleksandar Markovski, Iliyan Manoylov, Silviya Bradyanova, Nikolina Mihaylova, Andrey Tchorbanov, Irini Doytchinova
Publikováno v:
Pharmaceuticals, Vol 17, Iss 11, p 1498 (2024)
Objectives: SARS-CoV-2 caused the COVID-19 pandemic, which overwhelmed global healthcare systems. Over 776 million COVID-19 cases and more than 7 million deaths were reported by WHO in September 2024. COVID-19 vaccination is crucial for preventing in
Externí odkaz:
https://doaj.org/article/754cb726211547698e7a7e624bfe30a8
Autor:
Emiliya Stoyanova, Nikolina Mihaylova, Nikola Ralchev, Silviya Bradyanova, Iliyan Manoylov, Yuliana Raynova, Krassimira Idakieva, Andrey Tchorbanov
Publikováno v:
Marine Drugs, Vol 22, Iss 10, p 462 (2024)
Melanoma is one of the most common tumors worldwide, and new approaches and antitumor drugs for therapy are being investigated. Among the promising biomolecules of natural origin for antitumor research are gastropodan hemocyanins—highly immunogenic
Externí odkaz:
https://doaj.org/article/6060ec9bd7084ff7a0caffbbf2782aeb
Autor:
Emiliya Stoyanova, Nikolina Mihaylova, Nikola Ralchev, Silviya Bradyanova, Iliyan Manoylov, Yuliana Raynova, Krassimira Idakieva, Andrey Tchorbanov
Publikováno v:
Marine Drugs, Vol 22, Iss 5, p 220 (2024)
The development of antitumor drugs and therapy requires new approaches and molecules, and products of natural origin provide intriguing alternatives for antitumor research. Gastropodan hemocyanins-multimeric copper-containing glycoproteins have been
Externí odkaz:
https://doaj.org/article/536fdf99279347beb26bb404c9cfc328
Autor:
Blagovesta Boneva, Andrey Marchev, Kristiana Amirova, Petya Ganova, Milen Georgiev, Andrey Tchorbanov, Nikolina Mihaylova
Publikováno v:
Life, Vol 13, Iss 4, p 894 (2023)
Objectives: Osteoarthritis (OA) is an age-related joint disease that involves the degeneration of cartilage and is the most prevalent form of arthritis, affecting a large part of the population. OA is a multifactorial disorder, and no single etiologi
Externí odkaz:
https://doaj.org/article/c3f140ea8b14463fa451b6ea401343e3
Publikováno v:
Life, Vol 12, Iss 11, p 1938 (2022)
Objectives: Osteoarthritis (OA) is a chronic degenerative disorder of the joint characterized by cartilage breakdown and synovial inflammation. A number of different cells of innate and adaptive immunity contribute to joint pathology during OA inflam
Externí odkaz:
https://doaj.org/article/34334c4c6f06403cb3de084f5929533e
Autor:
Ganka Chaneva, Alexander Tomov, Momchil Paunov, Viktoria Hristova, Valentina Ganeva, Nikolina Mihaylova, Svetoslav Anev, Nikolay Krumov, Zhenya Yordanova, Boris Tsenov, Valya Vassileva, Georgi Bonchev, Miroslava Zhiponova
Publikováno v:
Plants, Vol 11, Iss 22, p 3181 (2022)
Ludisia discolor is commonly known as a jewel orchid due to its variegated leaves. Easy maintenance of the orchid allows it to be used as a test system for various fertilizers and nutrient sources, including aquaponic water (AW). First, we applied DN
Externí odkaz:
https://doaj.org/article/75f9fe6d97dd4fa7a18edf11693b905f
Autor:
Emiliya Stoyanova, Nikolina Mihaylova, Nikola Ralchev, Petya Ganova, Silviya Bradyanova, Iliyan Manoylov, Yuliana Raynova, Krassimira Idakieva, Andrey Tchorbanov
Publikováno v:
Marine Drugs, Vol 20, Iss 6, p 392 (2022)
Finding new effective compounds of natural origin for composing anti-tumor vaccines is one of the main goals of antitumor research. Promising anti-cancer agents are the gastropodan hemocyanins–multimeric copper-containing glycoproteins used so far
Externí odkaz:
https://doaj.org/article/b434c656d8c546509b9c68df39d8142e
Autor:
Nikolina Mihaylova, Silviya Bradyanova, Petroslav Chipinski, Melinda Herbáth, Stela Chausheva, Dobroslav Kyurkchiev, József Prechl, Andrey I. Tchorbanov
Publikováno v:
Autoimmunity, Vol 50, Iss 4, Pp 257-268 (2017)
Systemic lupus erythematosus (SLE) is a polygenic pathological disorder which involves multiple organs. Self-specific B cells play a main role in the lupus pathogenesis by generating autoantibodies as well as by serving as important autoantigen-prese
Externí odkaz:
https://doaj.org/article/b637d452e0664a0697b94700e5d22f04
Autor:
Vladimir Isachenko, Plamen Todorov, Evgenia Isachenko, Gohar Rahimi, Andrey Tchorbanov, Nikolina Mihaylova, Iliyan Manoylov, Peter Mallmann, Markus Merzenich
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212961 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0129108.].
Externí odkaz:
https://doaj.org/article/3a1c9108df0d47d1a2451541126ac34c
Autor:
Vladimir Isachenko, Plamen Todorov, Evgenia Isachenko, Gohar Rahimi, Andrey Tchorbanov, Nikolina Mihaylova, Iliyan Manoylov, Peter Mallmann, Markus Merzenich
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129108 (2015)
ObjectivesTo translocation (externalization) of phosphatidylserine lead at least the five negative effects observed during cells cryopreservation: hypoxia, increasing of intracellular Ca2+, osmotic disruption of cellular membranes, generation of reac
Externí odkaz:
https://doaj.org/article/a78efe5456a449e9869403490b82e633