Zobrazeno 1 - 10
of 349
pro vyhledávání: '"Nikolić Katarina"'
Publikováno v:
Acta Stomatologica Naissi, Vol 38, Iss 85, Pp 2352-2369 (2022)
Introduction: Oral cavity is the colonization site of most diverse microorganisms. The homeostasis of oral microbioma is affected by numerous factors. Periodontal diseases occur as a consequence of disturbed oral microbioma homeostasis, when an infla
Externí odkaz:
https://doaj.org/article/387051906177495db16be57741bc5f11
Publikováno v:
Arhiv za farmaciju, Vol 71, Iss 2, Pp 73-100 (2021)
Today, we are witnessing an explosion of scientific concepts in cancer chemotherapy. It has been considered for a long time that genetic instability in cancer should be treated with drugs that directly damage the DNA. Understanding the molecular basi
Externí odkaz:
https://doaj.org/article/75df15ceba1a42f7a8ebfa8c3c2a4111
Publikováno v:
Vojnosanitetski Pregled, Vol 78, Iss 9, Pp 1005-1008 (2021)
Introduction. The exact prevalence of benign familial neonatal epilepsy (BFNE) is unknown due to the likelihood of overlooking the disease and not diagnosing the affected patients correctly. The rare autosomal dominant inherited disorder usually occu
Externí odkaz:
https://doaj.org/article/9bd72d49d7684de38cc905a7e85cac2f
Publikováno v:
Arhiv za farmaciju, Vol 71, Iss 4, Pp 225-256 (2021)
Drug discovery and development is a very challenging, expensive and time-consuming process. Impressive technological advances in computer sciences and molecular biology have made it possible to use computer-aided drug design (CADD) methods in various
Externí odkaz:
https://doaj.org/article/689794985f5740c293310cd52fb619a0
Autor:
Nikolić Katarina, Vlajković Marina
Publikováno v:
Medicinski Podmladak, Vol 71, Iss 1, Pp 26-32 (2020)
Introduction: Neuroblastoma cells show the expression of norepinephrine transporters enabling the intercellular location of mIBG, which turned out to be ideal for the visualization of neuroblastoma, as well as for the treatment of these tumors in cer
Externí odkaz:
https://doaj.org/article/689cde8116f649c0b0a17890b3a0351f
Autor:
Nikolić Katarina, Vlajković Marina
Publikováno v:
Medicinski Podmladak, Vol 70, Iss 2, Pp 30-36 (2019)
Introduction: Differentiated thyroid carcinoma (DTC) derived from follicular cells is the most frequent endocrine malignancy, which most commonly occurs in patients with thyroid nodules. Aim: The aim of this retrospective analysis is to examine the t
Externí odkaz:
https://doaj.org/article/f109279f6deb45b59fd86e34cc03a286
Publikováno v:
Arhiv za farmaciju, Vol 68, Iss 4, Pp 860-873 (2018)
The importance of the activation of phosphatidylinositol-3-kinase (PI3K) in the processes of tumor cell formation and growth has brought great interest in the development of new antitumor drugs that inhibit the PI3K-Akt signaling pathway. Recent stud
Externí odkaz:
https://doaj.org/article/a3ac120c092541459cb74de0759fd753
Publikováno v:
Arhiv za farmaciju, Vol 67, Iss 3, Pp 165-179 (2017)
All tested compounds show agonistic activity onserotonin5-HT2areceptors, which activation causes neuronal excitations, behavioral changes and platelet aggregation. The main aims of this study were to create 3D-QSAR(3D-Quantitative structure-activity
Externí odkaz:
https://doaj.org/article/111574adc2a547da87d7416ebc6cedfc
Publikováno v:
Arhiv za farmaciju, Vol 67, Iss 4, Pp 233-247 (2017)
Creation of a statistically reliable 3D-QSAR (Quantitative Structure Activity Relationships) model enables definition of the structure of the pharmacophore for antagonists of serotonin 5-HT2A receptors and selection of the key molecular determinants
Externí odkaz:
https://doaj.org/article/bb2fcfef06d04d7d92be86daebeb3a57
Publikováno v:
Arhiv za farmaciju, Vol 65, Iss 5, Pp 287-303 (2015)
Drug discovery based on development of selective ligands for a specific target intended to modulate its activity and revert pathophysiological process is now recognized as too simplistic to design effective agent for complex multifactorial diseases,
Externí odkaz:
https://doaj.org/article/ae7a2ea78afd4136b5c4d0350d0f58fa