Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nikoletta Pechlivani"'
Autor:
Basmah Alsayejh, Noppadol Kietsiriroje, Mansour Almutairi, Katie Simmons, Nikoletta Pechlivani, Sreenivasan Ponnambalam, Ramzi A. Ajjan
Publikováno v:
TH Open, Vol 06, Iss 04, Pp e396-e407 (2022)
Abstract The vascular obstructive thrombus is composed of a mesh of fibrin fibers with blood cells trapped in these networks. Enhanced fibrin clot formation and/or suppression of fibrinolysis are associated with an increased risk of vascular occlusi
Externí odkaz:
https://doaj.org/article/c4ed8a57ea634e09829e465ce1a35a1e
Autor:
Nikoletta Pechlivani, Ramzi A. Ajjan
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Cardiovascular disease remains the main cause of morbidity and mortality in patients with diabetes. The risk of vascular ischemia is increased in this population and outcome following an event is inferior compared to individuals with normal glucose m
Externí odkaz:
https://doaj.org/article/45d4a024465741d9b532324a61b3fb5b
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12537, p 12537 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Thrombus formation remains a major cause of morbidity and mortality worldwide. Current antiplatelet and anticoagulant therapies have been effective at reducing vascular events, but at the expense of increased bleeding risk. Targeting proteins that in
Autor:
Khalid M. Naseem, Robert A. S. Ariëns, Rhodri King, Fraser L. Macrae, Katherine J. Kearney, Ramzi A. Ajjan, Christian Tiede, Kerrie A. Smith, Benjamin E. J. Spurgeon, Iain W. Manfield, Ramsah Cheah, Fladia Phoenix, Katie J. Simmons, Darren C. Tomlinson, Nikoletta Pechlivani, Michael J. McPherson
Publikováno v:
Blood. 133:1233-1244
Bleeding complications secondary to surgery, trauma, or coagulation disorders are important causes of morbidity and mortality. Although fibrin sealants are considered to minimize blood loss, this is not widely adopted because of its high cost and/or
Autor:
Minnah Sheikh, Gabrielle Whitney, Julia Burns, Marina Saisana, Athanasios Kaldis, Elizabeth R McCain, Vasilis C. Gegas, Amy T. Hark, Hanna Caiola, Athanasios Makris, Panagiotis Papoutsoglou, Jenna Kotak, Konstantinos E. Vlachonasios, John H. Doonan, Cyrus E. Kuschner, Nikoletta Pechlivani, Ashley Kendig
Publikováno v:
Planta. 248:613-628
The histone acetyltransferase GCN5 and associated transcriptional coactivator ADA2b are required to couple endoreduplication and trichome branching. Mutation of ADA2b also disrupts the relationship between ploidy and leaf cell size. Dynamic chromatin
Autor:
Fladia Phoenix, Natalie Oxley, Ramzi Ajjan, Nikolaos Kyriakakis, Khyatisha Seejore, Robert D Murray, Julie Lynch, Steve Orme, Nikoletta Pechlivani
Publikováno v:
Endocrine Abstracts.
Autor:
Natalie Oxley, Nikolaos Kyriakakis, Robert D Murray, Nikoletta Pechlivani, Julie Lynch, Ramzi A. Ajjan, Steve M. Orme, Khyatisha Seejore, Fladia Phoenix
Publikováno v:
European journal of endocrinology. 182(5)
Objective There remains increased cardiovascular mortality in patients with acromegaly. This study aims to evaluate whether GH/IGF-1 excess increases vascular disease by adversely affecting fibrin network characteristics. Design Cross-sectional study
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 3170, p 3170 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 3170, p 3170 (2021)
Hypofibrinolysis is a key abnormality in diabetes and contributes to the adverse vascular outcome in this population. Plasminogen activator inhibitor (PAI)-1 is an important regulator of the fibrinolytic process and levels of this antifibrinolytic pr