Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nikoleta Pavlaki"'
Autor:
Axel E. Kraft, Nadja I. Bork, Hariharan Subramanian, Nikoleta Pavlaki, Antonio V. Failla, Bernd Zobiak, Marco Conti, Viacheslav O. Nikolaev
Publikováno v:
Cells, Vol 13, Iss 6, p 476 (2024)
The ubiquitous second messenger 3′,5′-cyclic adenosine monophosphate (cAMP) regulates cardiac excitation-contraction coupling (ECC) by signaling in discrete subcellular microdomains. Phosphodiesterase subfamilies 4B and 4D are critically involved
Externí odkaz:
https://doaj.org/article/c82bc06ba3af4c549615d0745de94c45
Autor:
Tobias Benkel, Mirjam Zimmermann, Julian Zeiner, Sergi Bravo, Nicole Merten, Victor Jun Yu Lim, Edda Sofie Fabienne Matthees, Julia Drube, Elke Miess-Tanneberg, Daniela Malan, Martyna Szpakowska, Stefania Monteleone, Jak Grimes, Zsombor Koszegi, Yann Lanoiselée, Shannon O’Brien, Nikoleta Pavlaki, Nadine Dobberstein, Asuka Inoue, Viacheslav Nikolaev, Davide Calebiro, Andy Chevigné, Philipp Sasse, Stefan Schulz, Carsten Hoffmann, Peter Kolb, Maria Waldhoer, Katharina Simon, Jesus Gomeza, Evi Kostenis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Carvedilol is among the most effective β-blockers for improving survival after myocardial infarction. Yet the mechanisms by which carvedilol achieves this superior clinical profile are still unclear. Beyond blockade of β1-adrenoceptors, ar
Externí odkaz:
https://doaj.org/article/31913551d70443ecbc6be0521f89476a
Autor:
Nikoleta Pavlaki, Kirstie A. De Jong, Birgit Geertz, Viacheslav O. Nikolaev, Alexander Froese
Publikováno v:
Cells, Vol 10, Iss 3, p 535 (2021)
3′,5′-Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger which plays critical roles in cardiac function and disease. In adult mouse ventricular myocytes (AMVMs), several distinct functionally relevant microdomains with tightly
Externí odkaz:
https://doaj.org/article/3f4994f0220a42a5876fb76751398b50
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 4 (2018)
Cyclic nucleotides 3′,5′-cyclic adenosine monophosphate (cAMP) and 3′,5′-cyclic guanosine monophosphate (cGMP) are important second messengers that regulate cardiovascular function and disease by acting in discrete subcellular microdomains. S
Externí odkaz:
https://doaj.org/article/87b4661b3f6449548477c25bec17255c
Autor:
Catherine D. E. Wilder, Ellice Caldwell-Dunn, Michael J. Curtis, Antonella Ranieri, Tutku Dursun, Hannah R. Lewis, Paul Gyimah, Nikoleta Pavlaki
Publikováno v:
British Journal of Pharmacology. 175:1669-1690
BACKGROUND & PURPOSE: Antiarrhythmic β-blockers are used in patients at risk of myocardial ischaemia, but the survival benefit and mechanisms are unclear. We hypothesised that β-blockers do not prevent ventricular fibrillation (VF), but instead inh
Autor:
Kirstie A. De Jong, Viacheslav O. Nikolaev, Birgit Geertz, Nikoleta Pavlaki, Alexander Froese
Publikováno v:
Cells, Vol 10, Iss 535, p 535 (2021)
Cells
Volume 10
Issue 3
Cells
Volume 10
Issue 3
3′,5′-Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger which plays critical roles in cardiac function and disease. In adult mouse ventricular myocytes (AMVMs), several distinct functionally relevant microdomains with tightly
Publikováno v:
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 4 (2018)
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 4 (2018)
Cyclic nucleotides 3′,5′-cyclic adenosine monophosphate (cAMP) and 3′,5′-cyclic guanosine monophosphate (cGMP) are important second messengers that regulate cardiovascular function and disease by acting in discrete subcellular microdomains. S
Autor:
Catherine D E, Wilder, Nikoleta, Pavlaki, Tutku, Dursun, Paul, Gyimah, Ellice, Caldwell-Dunn, Antonella, Ranieri, Hannah R, Lewis, Michael J, Curtis
Publikováno v:
British journal of pharmacology. 175(10)
BACKGROUND AND PURPOSE: Antiarrhythmic β‐blockers are used in patients at risk of myocardial ischaemia, but the survival benefit and mechanisms are unclear. We hypothesized that β‐blockers do not prevent ventricular fibrillation (VF) but instea