Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Nikolce Gjorevski"'
Autor:
S Jordan Kerns, Chaitra Belgur, Debora Petropolis, Marianne Kanellias, Riccardo Barrile, Johannes Sam, Tina Weinzierl, Tanja Fauti, Anne Freimoser-Grundschober, Jan Eckmann, Carina Hage, Martina Geiger, Patrick Ray Ng, William Tien-Street, Dimitris V Manatakis, Virginie Micallef, Regine Gerard, Michael Bscheider, Ekaterina Breous-Nystrom, Anneliese Schneider, Anna Maria Giusti, Cristina Bertinetti-Lapatki, Heather Shannon Grant, Adrian B Roth, Geraldine A Hamilton, Thomas Singer, Katia Karalis, Annie Moisan, Peter Bruenker, Christian Klein, Marina Bacac, Nikolce Gjorevski, Lauriane Cabon
Publikováno v:
eLife, Vol 10 (2021)
Traditional drug safety assessment often fails to predict complications in humans, especially when the drug targets the immune system. Here, we show the unprecedented capability of two human Organs-on-Chips to evaluate the safety profile of T-cell bi
Externí odkaz:
https://doaj.org/article/65e3b07242e4472a8bccea9ce9f5ca1b
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Intestinal stem cells are located at the base of the crypts and are surrounded by a complex structure called niche. This environment is composed mainly of epithelial cells and stroma which provides signals that govern cell maintenance, proliferation,
Externí odkaz:
https://doaj.org/article/1f1d21106f6245fc8e551d5e8272225d
Autor:
Gerald Schwank, Sylke Hoehnel, Matthias P. Lutolf, Nikolce Gjorevski, Fabien Kuttler, Camilla Ceroni, Krisztian Homicsko, Nathalie Brandenberg, Till Ringel, George Coukos, Gerardo Turcatti
Publikováno v:
Nature Biomedical Engineering. 4:863-874
Stem-cell-derived epithelial organoids are routinely used for the biological and biomedical modelling of tissues. However, the complexity, lack of standardization and quality control of stem cell culture in solid extracellular matrices hampers the ro
Autor:
Anne Freimoser-Grundschober, Ekaterina Breous-Nystrom, Heather Shannon Grant, Chaitra Belgur, Carina Hage, Anna Maria Giusti, Régine Gérard, Patrick Ray Ng, Martina Geiger, Lauriane Cabon, Adrian Roth, Katia Karalis, Nikolce Gjorevski, Tanja Fauti, Dimitris V. Manatakis, Johannes Sam, Christian Klein, William Tien-Street, Tina Weinzierl, Virginie Micallef, Thomas Singer, Anneliese Schneider, Debora B. Petropolis, Annie Moisan, Peter Bruenker, Jan Eckmann, Geraldine A. Hamilton, S. Jordan Kerns, Cristina Bertinetti-Lapatki, Riccardo Barrile, Michael Bscheider, Marina Bacac, Marianne Kanellias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3636b0fb4a5bf02fa3e3ab9b2eb29a8
https://doi.org/10.7554/elife.67106.sa2
https://doi.org/10.7554/elife.67106.sa2
Autor:
Katia Karalis, Anneliese Schneider, Riccardo Barrile, Annie Moisan, Peter Bruenker, William Tien-Street, Michael Bscheider, Patrick Ray Ng, Régine Gérard, Tanja Fauti, Anna Maria Giusti, Debora B. Petropolis, Ekaterina Breous-Nystrom, Marina Bacac, Johannes Sam, Thomas Singer, Adrian Roth, Nikolce Gjorevski, Tina Weinzierl, Virginie Micallef, Lauriane Cabon, Dimitris V. Manatakis, Carina Hage, Cristina Bertinetti-Lapatki, Jan Eckmann, Geraldine A. Hamilton, Christian Klein, S. Jordan Kerns, Chaitra Belgur, Marianne Kanellias, Anne Freimoser-Grundschober, Heather Shannon Grant, Martina Geiger
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Traditional drug safety assessment often fails to predict complications in humans, especially when the drug targets the immune system. Here, we show the unprecedented capability of two Organs-on-Chips to evaluate the safety profile of T-cell bispecif
Autor:
Mikhail Nikolaev, Yoji Tabata, Nathalie Brandenberg, Nicolas Broguiere, Matthias P. Lutolf, Olga Mitrofanova, Sara Geraldo, Nikolce Gjorevski
Organoids derived from epithelial stem cells have emerged as powerful platforms to model development and disease in a dish1-3. However, the current mismatch in anatomy, lifespan and size between native organs and their in vitro counterparts severely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7635e22ca302e18430694f77f1f76e4b
https://doi.org/10.21203/rs.3.pex-903/v1
https://doi.org/10.21203/rs.3.pex-903/v1
Autor:
Annie Moisan, Adrian Roth, Nikolce Gjorevski, Blandine Avignon, Lauriane Cabon, Régine Gérard, Michael Bscheider
Publikováno v:
Lab on a chip. 20(18)
The multiphasic etiology of tissue inflammation and the fundamental immunological differences between species render inflammatory pathologies difficult to recapitulate in animal models, and account for the paucity of therapies that are successfully t
Publikováno v:
Advanced Functional Materials
Publikováno v:
Biomaterials. 276:121020
Organoids are a new class of biological model systems that have garnered significant interest in the life sciences. When provided with the proper 3D matrix and biochemical factors, stem cells can self-organize and form tissue-specific organoids. Thus
Autor:
Nathalie, Brandenberg, Sylke, Hoehnel, Fabien, Kuttler, Krisztian, Homicsko, Camilla, Ceroni, Till, Ringel, Nikolce, Gjorevski, Gerald, Schwank, George, Coukos, Gerardo, Turcatti, Matthias P, Lutolf
Publikováno v:
Nature biomedical engineering. 4(9)
Stem-cell-derived epithelial organoids are routinely used for the biological and biomedical modelling of tissues. However, the complexity, lack of standardization and quality control of stem cell culture in solid extracellular matrices hampers the ro