Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Nikolay G. Kolev"'
An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
A Variant Surface Glycoprotein (VSG) coat protects bloodstream form T. brucei. Applying super-resolution microscopy Budzak et al. characterize a set of nuclear bodies, which associate with the active expression site in bloodstream form T. brucei and
Externí odkaz:
https://doaj.org/article/512b5528a291459196d3659ae386f264
Autor:
Justin Y. Toh, Agathe Nkouawa, Saúl Rojas Sánchez, Huafang Shi, Nikolay G. Kolev, Christian Tschudi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Trypanosoma brucei is a protozoan parasite that causes important human and livestock diseases in sub-Saharan Africa. By overexpressing a single RNA-binding protein, RBP6, in non-infectious procyclics trypanosomes, we previously recapitulated
Externí odkaz:
https://doaj.org/article/da1fde26a8c943f3b0cd78d7331bc63a
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011438 (2023)
Cold shock proteins are members of a family of DNA- and RNA-binding proteins with one or more evolutionarily conserved cold shock domain (CSD). These proteins have a wide variety of biological functions, including DNA-damage repair, mRNA stability, a
Externí odkaz:
https://doaj.org/article/3fc52aa053994c9e83f5327530c67c7e
Autor:
Kazimierz T. Tycowski, Huafang Shi, Shulamit Michaeli, Justin Y. Toh, K. Shanmugha Rajan, Yuling Lei, Nikolay G. Kolev, Christian Tschudi
Publikováno v:
Journal of Biological Chemistry. 294:15559-15574
The vault ribonucleoprotein (RNP), comprising vault RNA (vtRNA) and telomerase-associated protein 1 (TEP1), is found in many eukaryotes. However, previous studies of vtRNAs, for example in mammalian cells, have failed to reach a definitive conclusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63dae7b7e8b4f5d900f1704f835e9ed6
https://doi.org/10.1074/jbc.ra119.008580
https://doi.org/10.1074/jbc.ra119.008580
Autor:
Justin Y. Toh, Christian Tschudi, Saúl Rojas Sánchez, Nikolay G. Kolev, Huafang Shi, Agathe Nkouawa
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Trypanosoma brucei is a protozoan parasite that causes important human and livestock diseases in sub-Saharan Africa. By overexpressing a single RNA-binding protein, RBP6, in non-infectious procyclics trypanosomes, we previously recapitulated in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20900dc52ce426af36586aa82eb7ee32
https://pubmed.ncbi.nlm.nih.gov/33707699
https://pubmed.ncbi.nlm.nih.gov/33707699
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002678 (2012)
The introduction ten years ago of RNA interference (RNAi) as a tool for molecular exploration in Trypanosoma brucei has led to a surge in our understanding of the pathogenesis and biology of this human parasite. In particular, a genome-wide RNAi scre
Externí odkaz:
https://doaj.org/article/2c76ab3c1b384ddcab99fb13a4f36f53
Publikováno v:
Molecular and Biochemical Parasitology. 226:20-23
Trypanosoma brucei relies on two types of variant surface glycoprotein (VSG) expression sites (ESs) for RNA polymerase I (Pol I) transcription of VSG pre-mRNA. Trypanosomes developing into infectious metacyclic cells in the tsetse vector use metacycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9dba5276e47c0eff126cc640f93881c
https://doi.org/10.1016/j.molbiopara.2018.10.003
https://doi.org/10.1016/j.molbiopara.2018.10.003
Autor:
Nikolay G Kolev, Joseph B Franklin, Shai Carmi, Huafang Shi, Shulamit Michaeli, Christian Tschudi
Publikováno v:
PLoS Pathogens, Vol 6, Iss 9, p e1001090 (2010)
The genome of Trypanosoma brucei, the causative agent of African trypanosomiasis, was published five years ago, yet identification of all genes and their transcripts remains to be accomplished. Annotation is challenged by the organization of genes tr
Externí odkaz:
https://doaj.org/article/4fd61784825c4fec8d4c9042d7891286
Autor:
Tirza Doniger, Shulamit Michaeli, Smadar Cohen-Chalamish, Nikolay G. Kolev, Elisabetta Ullu, Nasreen Hag Yahia, Sachin Kumar Gupta, Christian Tschudi, Hiba Waldman Ben-Asher, Liat Kolet, Vaibhav Chikne, K. Shanmugha Rajan, Ron Unger
Publikováno v:
Journal of Molecular Biology. 429:3301-3318
The parasite Trypanosoma brucei is the causative agent of African sleeping sickness and is known for its unique RNA processing mechanisms that are common to all the kinetoplastidea including Leishmania and Trypanosoma cruzi. Trypanosomes possess two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07420ad1b6e987cea9a0edcc521528c
https://doi.org/10.1016/j.jmb.2017.04.015
https://doi.org/10.1016/j.jmb.2017.04.015
Autor:
Romain Christiano, Tobias C. Walther, Huafang Shi, Nikolay G. Kolev, Christian Tschudi, Elisabetta Ullu
Publikováno v:
Molecular Microbiology. 106:74-92
The infectious metacyclic forms of Trypanosoma brucei result from a complex development in the tsetse fly vector. When they infect mammals, they cause African sleeping sickness in humans. Due to scarcity of biological material and difficulties of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d88791c2d1f9805c30534315881b23d
https://doi.org/10.1111/mmi.13754
https://doi.org/10.1111/mmi.13754