Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nikolay E. Kushlinskii"'
Autor:
Olga V. Kovaleva, Polina A. Podlesnaya, Ekaterina S. Kudinova, Valeria V. Mochalnikova, Nikolay E. Kushlinskii, Alexey N. Gratchev
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 4, Pp 189-196 (2024)
Rationale: Long non-coding RNAs (lncRNAs) influence tumor cell properties during the onset and progression of lung malignancies; however, their diagnostic and prognostic significance has not been determined. We have previously shown that when non-sma
Externí odkaz:
https://doaj.org/article/ffe96e95ecd94f978e550508008dc21d
Autor:
Nikolay E. Kushlinskii, Olga V. Kovaleva, Arseniy G. Basov, Yurii B. Kuzmin, Aleksandr A. Alferov, Svetlana D. Bezhanova, Aleksey V. Kolpashchikov, Igor A. Klimanov, Alexey N. Grachev, Natalia N. Zybina, Vsevolod B. Matveev, Oleg O. Yanushevich, Ivan S. Stilidi
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 3, Pp 107-119 (2024)
Background: Galectins are a family of β-galactoside binding proteins that regulate the vast majority of cellular functions, including proliferation, migration, adhesion, and phagocytosis in both health and disease. More and more experimental and cli
Externí odkaz:
https://doaj.org/article/3dc7de3dbc9b49969eb33690ddc7e80c
Autor:
Ulyana A. Boyarskih, Andrey A. Kechin, Alyona V. Zyuzyukina, Yevgeny A. Khrapov, Igor P. Oscorbin, Yefim Y. Alexeenok, Galina A. Avdiyuk, Ruslan A. Zukov, Nikolay E. Kushlinskii, Maksim L. Filipenko
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 3, Pp 132-139 (2024)
Background: For effective screening of breast cancer patients for candidates for target therapy with alpelisib, it is necessary to identify activating somatic mutations in the PIK3CA gene by allele specific polymerase chain reaction (PCR); this requi
Externí odkaz:
https://doaj.org/article/066dd6030c43452ba3308b2541346f48
Autor:
Yuri D. Ivanov, Ekaterina D. Nevedrova, Angelina V. Vinogradova, Kristina V. Goldaeva, Tatyana O. Pleshakova, Rafael A. Galiullin, Alexander N. Ableev, Ivan D. Shumov, Andrey F. Kozlov, Vladimir P. Popov, Nikolay E. Kushlinskii, Ivan S. Stilidi, Zaman Z. Mamedli, Dmitry V. Enikeev, Natalia V. Potoldykova, Vladimir A. Konev, Oleg B. Kovalev, Vadim S. Ziborov, Leonid I. Grishin, Alexander Y. Dolgoborodov, Oleg F. Petrov, Alexander I. Archakov
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 3, Pp 120-131 (2024)
Rationale: Colorectal cancer (CRC) is one of the most prevalent oncological diseases with high mortality. Invasive optical (endoscopic) colono- scopy has been recognized as a golden standard for the CRC diagnostics. A promising area is the developmen
Externí odkaz:
https://doaj.org/article/22f430a0240641ffbc212c3f691b49e1
Autor:
Tatiana N. Zabotina, Antonina I. Chertkova, Anna A. Borunova, Nikolay E. Kushlinskii, Elena S. Gershtein, Elena N. Zakharova, Esma K. Shoua, Vasily T. Tsiklauri, Igor V. Samoylenko, Maxim V. Khoroshilov, Zaira G. Kadagidze
Publikováno v:
Современная онкология, Vol 25, Iss 3, Pp 301-307 (2023)
Background. The PD-1/PD-L1 pathway plays an important role in tumor evasion from immunological surveillance. In addition to the membrane forms of PD-1 and PD-L1, there are soluble variants: sPD-1 and sPD-L1. Both membrane and soluble forms have immun
Externí odkaz:
https://doaj.org/article/03217cc7200040a588ddd35a922d7771
Autor:
Eugene I. Goufman, Nataliia B. Tikhonova, Andrey P. Aleksankin, Karina B. Gershkovich, Alexander A. Stepanov, Irina I. Stepanova, Liudmila M. Mikhaleva, Natalia V. Nizyaeva, Olga V. Kovaleva, Alexander A. Alferov, Yury B. Kuzmin, Nikolay E. Kushlinskii
Publikováno v:
Diagnostics, Vol 14, Iss 13, p 1396 (2024)
Blood serum of patients with gastric (n = 68) and esophageal (n = 43) cancer was assessed for proteolytic fragments of IgG. Serum samples of 20 healthy donors were used as a control. We analyzed indicators of hemostasis (prothrombin time, fibrinogen,
Externí odkaz:
https://doaj.org/article/31352469157745778be8befeaa984628
Autor:
Ludmila I. Velikanova, Natalia V. Vorokhobina, Zulfiya R. Shafigullina, Valentina V. Kalugina, Ekaterina V. Malevanaya, Elena G. Strelnikova, Maria O. Buinova, Aleksandr A. Lisitsyn, Nikolay E. Kushlinskii
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 51, Iss 3, Pp 143-153 (2023)
Background: Adrenocortical cancer (ACC) is a rare aggressive and rapidly metastatic disease. Early diagnosis of the disease and its metastatic stage are important for the choice of treatment strategy. Evaluation of urine steroid profiles (USP) by gas
Externí odkaz:
https://doaj.org/article/44a9522377d94469908369a3d49453d2
Autor:
Vadim B. Krylov, Anton N. Kuznetsov, Alina V. Polyanskaya, Pavel V. Tsarapaev, Dmitry V. Yashunsky, Nikolay E. Kushlinskii, Nikolay E. Nifantiev
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Mannans are polysaccharide antigens expressed on the cell wall of different fungal species including Saccharomyces cerevisiae and Candida spp. These fungi are components of the normal intestinal microflora, and the presence of antibodies to fungal an
Externí odkaz:
https://doaj.org/article/eb06535752d64760b121aaeebae9a017
Autor:
Ekaterina A. Korotkova, Elena S. Gershtein, Ekaterina V. Samoilova, Irina O. Goryacheva, Aram P. Petrosyan, Natalia N. Zybina, Oleg O. Yanushevich, Ivan S. Stilidi, Nikolay E. Kushlinskii
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 51, Iss 1, Pp 23-31 (2023)
Background: High incidence of gastric cancer (GC), its aggressive clinical course, rapid tumor dissemination, low sensitivity to chemotherapy and lack of reliable laboratory diagnostic criteria urgently require a search for the most informative marke
Externí odkaz:
https://doaj.org/article/9e579446db2345808e6179ba9139e706
Autor:
Anastasia P. Koval, Alexandra S. Khromova, Konstantin A. Blagodatskikh, Yulia V. Zhitnyuk, Yanina A. Shtykova, Aleksandr A. Alferov, Nikolay E. Kushlinskii, Dmitry S. Shcherbo
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Cell-free DNA (cfDNA) testing is the core of most liquid biopsy assays. In particular, cfDNA fragmentation features could facilitate non-invasive cancer detection due to their interconnection with tumor-specific epigenetic alterations. However, the f
Externí odkaz:
https://doaj.org/article/4188525145304295968eb034c4c209bd