Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Nikolay B, Pestov"'
Autor:
Abdul-Saleem Amoah, Nikolay B. Pestov, Tatyana V. Korneenko, Igor A. Prokhorenko, Georgy F. Kurakin, Nickolai A. Barlev
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3961 (2024)
The persisting presence of opportunistic pathogens like Pseudomonas aeruginosa poses a significant threat to many immunocompromised cancer patients with pulmonary infections. This review highlights the complexity of interactions in the host’s defen
Externí odkaz:
https://doaj.org/article/110166bb1413414bb052eb7154eefc7d
Autor:
Gleb S. Ivanov, Vyacheslav G. Tribulovich, Nikolay B. Pestov, Temitope I. David, Abdul-Saleem Amoah, Tatyana V. Korneenko, Nikolai A. Barlev
Publikováno v:
Biology Direct, Vol 17, Iss 1, Pp 1-21 (2022)
Abstract Originally discovered by Nielsen in 1991, peptide nucleic acids and other artificial genetic polymers have gained a lot of interest from the scientific community. Due to their unique biophysical features these artificial hybrid polymers are
Externí odkaz:
https://doaj.org/article/a9ee53a3af80442ba86a886ad8ba03b3
Autor:
Tatyana V. Korneenko, Nikolay B. Pestov, Ivan A. Nevzorov, Alexandra A. Daks, Kirill N. Trachuk, Olga N. Solopova, Nickolai A. Barlev
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1675 (2023)
The evolutionary conserved DNA-sensing cGAS-STING innate immunity pathway represents one of the most important cytosolic DNA-sensing systems that is activated in response to viral invasion and/or damage to the integrity of the nuclear envelope. The k
Externí odkaz:
https://doaj.org/article/8eef0a70b5e841dcbe8118096edea3ba
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 22 (2023)
In this review, we discuss the long-known problem of tissue-specific carcinogenesis in BRCA1 and BRCA2 mutation carriers: while the genes are expressed ubiquitously, increased cancer risk is observed mostly in the breast and ovaries, and to a much le
Externí odkaz:
https://doaj.org/article/5b1173af1e174ddeb1cb0d9f0f087f86
Autor:
Alina S. Nazarenko, Mikhail F. Vorovitch, Yulia K. Biryukova, Nikolay B. Pestov, Ekaterina A. Orlova, Nickolai A. Barlev, Nadezhda M. Kolyasnikova, Aydar A. Ishmukhametov
Publikováno v:
Viruses, Vol 15, Iss 10, p 1973 (2023)
Oncolytic viruses offer a promising approach to tumor treatment. These viruses not only have a direct lytic effect on tumor cells but can also modify the tumor microenvironment and activate antitumor immunity. Due to their high pathogenicity, flavivi
Externí odkaz:
https://doaj.org/article/45a5bb0a6e5249c397ee6768abe872c4
Autor:
Anna P. Loboda, Leonid S. Adonin, Svetlana D. Zvereva, Dmitri Y. Guschin, Tatyana V. Korneenko, Alexandra V. Telegina, Olga K. Kondratieva, Sofia E. Frolova, Nikolay B. Pestov, Nick A. Barlev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4982 (2023)
Two related tumor suppressor genes, BRCA1 and BRCA2, attract a lot of attention from both fundamental and clinical points of view. Oncogenic hereditary mutations in these genes are firmly linked to the early onset of breast and ovarian cancers. Howev
Externí odkaz:
https://doaj.org/article/d3866f5587df4245b4132d5fa2136a59
Autor:
Nisar Ahmad, Ivana L. de la Serna, Himangi G. Marathe, Xiaoming Fan, Prabhatchandra Dube, Shungang Zhang, Steven T. Haller, David J. Kennedy, Nikolay B. Pestov, Nikolai N. Modyanov
Publikováno v:
Life, Vol 13, Iss 2, p 414 (2023)
Vertebrate ATP1B4 genes represent a rare instance of orthologous gene co-option, resulting in radically different functions of the encoded BetaM proteins. In lower vertebrates, BetaM is a Na, K-ATPase β-subunit that is a component of ion pumps in th
Externí odkaz:
https://doaj.org/article/6e2ef6f1976b45d49fbfa027ede664ac
Autor:
Alla Y. Molchanova, Svetlana N. Rjabceva, Tigran B. Melik-Kasumov, Nikolay B. Pestov, Plamena R. Angelova, Vadim V. Shmanai, Olga L. Sharko, Andrei V. Bekish, Genevieve James, Hui Gyu Park, Irina A. Udalova, J. Thomas Brenna, Mikhail S. Shchepinov
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 681 (2022)
Arachidonic acid (ARA) is a major component of lipid bilayers as well as the key substrate for the eicosanoid cascades. ARA is readily oxidized, and its non-enzymatic and enzymatic oxidation products induce inflammatory responses in nearly all tissue
Externí odkaz:
https://doaj.org/article/77209d44acb742b8a46aa6c9f62d2c9b
Autor:
Nikolay B. Pestov, Nadezhda M. Kolyasnikova, Jeanne P. Sanchez-Pimentel, Nikolay A. Barlev, Aidar A. Ishmukhametov
Publikováno v:
Current Pharmaceutical Biotechnology. 24:266-278
Abstract: The idea of using the lytic power of viruses against malignant cells has been entertained for many decades. However, oncolytic viruses gained broad attention as an emerging anti-cancer therapy only recently with the successful implementatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e351dc96bd49190ea73b67eaa9797738
https://doi.org/10.2174/1389201023666220516121813
https://doi.org/10.2174/1389201023666220516121813
Autor:
Nikolay B. Pestov, Daniel V. Kalinovsky, Tatyana D. Larionova, Alia Z. Zakirova, Nikolai N. Modyanov, Irina A. Okkelman, Tatyana V. Korneenko
Publikováno v:
PeerJ, Vol 7, p e6691 (2019)
Background Lysyl oxidases (LOX) have been extensively studied in mammals, whereas properties and functions of recently found homologues in prokaryotic genomes remain enigmatic. Methods LOX open reading frame was cloned from Haloterrigena turkmenica i
Externí odkaz:
https://doaj.org/article/540564c0db0648839130e5d2570ef420