Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nikolaus Mendler"'
Autor:
Ralf, Günzinger, Stephen M, Wildhirt, Hubert, Schad, Werner, Heimisch, Manuela, Gurdan, Nikolaus, Mendler, Joachim, Grammer, Rüdiger, Lange, Robert, Bauernschmitt
Publikováno v:
Basic Research in Cardiology. 102:508-517
Cardiopulmonary bypass (CPB) is known to induce systemic inflammation and cardiac dysfunction associated with a significant morbidity. Aim of the study was to develop an in vivo model of rat CPB with hypothermic cardiac arrest and the use of cardiopl
Autor:
Nikolaus Mendler, Peter Tassani, Ursula Ettner, Angelika Bernhard-Abt, Rüdiger Lange, Heimisch W, Hubert Schad
Publikováno v:
Cardiovascular Drugs and Therapy. 16:435-441
The calcium sensitizer levosimendan (LEV) improves the function of stunned myocardium, cardiac performance in heart failure, and possibly the efficiency of myocardial work. The present experiments investigated the effect of LEV on myocardial contract
Publikováno v:
Cardiovascular Engineering: An International Journal. 1:93-99
The severity of coronary artery (CA) disease depends on the degree of CA stenosis possibly aggravated by an O2 deficiency in the blood and the CA architecture. To analyze the functional response of the myocardium to hypoxia provoked by different meth
Autor:
Hans Meisner, Klaus Holper, Sung Un Paek, Michael Homann, John Cristoph Haehnel, Nikolaus Mendler, Rüdiger Lange
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 17:624-630
Objective: The reconstruction of the RVOT in congenital heart disease often requires the implantation of a valved conduit. Although allografts are considered the conduit of choice their availability is limited and therefore xenografts are implanted a
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 17:325-330
Objective: Biventricular bypass (BVB) with autologous lung perfusion is an attractive concept to ameliorate systemic inflammatory response by eliminating the oxygenator from the extracorporeal circulation. The effect of biventricular bypass as compar
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 14:503-507
Background: The significance of cellular viability in human valve allografts for functional clinical longevity continues to be debated. Meaningful tests for this biological entity are therefore in demand to quantify the relative merits of graft origi
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 13:710-717
Objective: Post-ischaemic stunned myocardium shows an impaired function at restored coronary blood flow, but performance can be normalized by positive inotropic stimulation. The power of stunned myocardium, however, is not augmented with increasing h
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 11:1125-1132
Objective: Most mammalian cardiac muscles show a positive force-frequency relation, which is turned into a negative relation in failing hearts. Stunned myocardium shows similar defects as failing myocardium, it has a functional reserve recruitable by
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 6:S17-S24
In an experimental study of 31 anesthetized dogs the importance of the mitral apparatus for the left ventricular function was investigated. During extracorporeal circulation bileaflet mitral valve prostheses were implanted preserving the mitral subva
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 5:598-602
Intracoronary injection of papaverine is used to determine coronary flow reserve in patients. The present study was to investigate the effect of papaverine on the performance of myocardium with reduced flow reserve. In nine anaesthetized open-chest d