Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nikolaus Deigendesch"'
Autor:
Chiara Stüdle, Hideaki Nishihara, Sven Wischnewski, Laila Kulsvehagen, Sylvain Perriot, Hiroshi Ishikawa, Horst Schroten, Stephan Frank, Nikolaus Deigendesch, Renaud Du Pasquier, Lucas Schirmer, Anne-Katrin Pröbstel, Britta Engelhardt
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background As a consequence of SARS-CoV-2 infection various neurocognitive and neuropsychiatric symptoms can appear, which may persist for several months post infection. However, cell type-specific routes of brain infection and underlying me
Externí odkaz:
https://doaj.org/article/d9433b49b0e545ddb46501b777be8935
Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease
Autor:
Barbara Bettegazzi, Laura Sebastian Monasor, Serena Bellani, Franca Codazzi, Lisa Michelle Restelli, Alessio Vittorio Colombo, Nikolaus Deigendesch, Stephan Frank, Takashi Saito, Takaomi C. Saido, Sven Lammich, Sabina Tahirovic, Fabio Grohovaz, Daniele Zacchetti
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-14 (2021)
Abstract Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder. Increased Aβ production plays a fundamental role in the pathogenesis of the disease and BACE1, the protease that triggers the amyloidogenic processing of
Externí odkaz:
https://doaj.org/article/0432a5c706c549658e2f87056cfe8f8a
Autor:
Jakob M Bader, Philipp E Geyer, Johannes B Müller, Maximilian T Strauss, Manja Koch, Frank Leypoldt, Peter Koertvelyessy, Daniel Bittner, Carola G Schipke, Enise I Incesoy, Oliver Peters, Nikolaus Deigendesch, Mikael Simons, Majken K Jensen, Henrik Zetterberg, Matthias Mann
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 6, Pp 1-17 (2020)
Abstract Neurodegenerative diseases are a growing burden, and there is an urgent need for better biomarkers for diagnosis, prognosis, and treatment efficacy. Structural and functional brain alterations are reflected in the protein composition of cere
Externí odkaz:
https://doaj.org/article/80195a6e8c6a486e943130141f08bd7a
Autor:
Philipp S. Fuchs, Jonas Lötscher, Caroline M. Berkemeier, Julia R. Hirsiger, Adhideb Ghosh, Quan-Zhen Li, Nikolaus Deigendesch, Emanuel Christ, Alexander A. Navarini, Mike Recher, Thomas Daikeler, Ingmar A. F. M. Heijnen, Christoph T. Berger
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundANCA-associated vasculitis (AAV) and Sjögren’s syndrome (SS) are uncommon autoimmune diseases. The co-occurrence in the same patient has been rarely described. Acromegaly has been associated with autoimmune thyroiditis, but the prevalenc
Externí odkaz:
https://doaj.org/article/519ffe4a909d4784ab512654423d8dfd
Autor:
André Maier, Nikolaus Deigendesch, Kathrin Müller, Jochen H Weishaupt, Alexander Krannich, Robert Röhle, Felix Meissner, Kaaweh Molawi, Christoph Münch, Teresa Holm, Robert Meyer, Thomas Meyer, Arturo Zychlinsky
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139684 (2015)
Preclinical studies show that blocking Interleukin-1 (IL-1) retards the progression of Amyotrophic Lateral Sclerosis (ALS). We assessed the safety of Anakinra (ANA), an IL-1 receptor antagonist, in ALS patients. In a single arm pilot study we treated
Externí odkaz:
https://doaj.org/article/56643e57e39e454ba13da7bb1eceeff4
Autor:
Maja Weisser, Nina Khanna, Anemone Hedstueck, Sarah Tschudin Sutter, Sandra Roesch, Gregor Stehle, Mihaela Sava, Nikolaus Deigendesch, Manuel Battegay, Laura Infanti, Andreas Holbro, Stefano Bassetti, Hans Pargger, Hans H. Hirsch, Karoline Leuzinger, Laurent Kaiser, Diem‐Lan Vu, Katharina Baur, Nadine Massaro, Michael Paul Busch, Graham Simmons, Mars Stone, Philip L. Felgner, Rafael R. de Assis, Saahir Khan, Cheng‐ting Tsai, Peter V. Robinson, David Seftel, Johannes Irsch, Anil Bagri, Andreas S. Buser, Laurence Corash
Publikováno v:
Transfusion. 62(10)
Efficacy of donated COVID-19 convalescent plasma (dCCP) is uncertain and may depend on antibody titers, neutralizing capacity, timing of administration, and patient characteristics.In a single-center hypothesis-generating prospective case-control stu
Autor:
Nikolaus Deigendesch, Mike Recher, Henrik Köhler, Christoph Berger, Ingmar Heijnen, Ezra Burstein, Annette Rovina, Corinne Légeret, Thomas Daikeler, Benedikt J. Meyer
Publikováno v:
Journal of Clinical Immunology
Autor:
Andreas Lindner, Arne Schröder, Christina Oetzmann von Sochaczewski, Jan Baumgart, Axel Heimann, Oliver J. Muensterer, Nikolaus Deigendesch
Publikováno v:
European Surgical Research. 61:95-100
Introduction: Swine had special roles in the development of minimally invasive procedures to treat vesicoureteral reflux, and minipigs have been gaining ground in recent years in experimental pediatric urology as they combine small size with less vul
Autor:
Mike Recher, Dorothee Harder, Christoph Berger, Joaquín M. Espinosa, Julia R. Hirsiger, Alexander A. Navarini, Thomas Daikeler, Nikolaus Deigendesch, Annaïse Jauch, Marc B. Bigler, Adhideb Ghosh
Publikováno v:
Rheumatology (Oxford)
Publikováno v:
Der Nervenarzt. 90:623-641
Eine Vielzahl unterschiedlicher Parasiten und Pilze kann zu Infektionen des zentralen Nervensystems (ZNS) fuhren und je nach Lokalisation unterschiedliche klinische Symptome und Verlaufe zeigen. Die Pravalenz von ZNS-Infektionen hangt von vielen Fakt