Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Nikolaus Gassler"'
Autor:
Paola Berenice Mass-Sanchez, Marinela Krizanac, Paula Štancl, Marvin Leopold, Kathrin M. Engel, Eva Miriam Buhl, Josef van Helden, Nikolaus Gassler, Jürgen Schiller, Rosa Karlić, Diana Möckel, Twan Lammers, Steffen K. Meurer, Ralf Weiskirchen, Anastasia Asimakopoulos
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The molecular mechanisms underlying the transition from nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC) are incompletely understood. During the development of NAFLD, Perilipin 5 (PLIN5) can regulate lipid metabolis
Externí odkaz:
https://doaj.org/article/2fdd9001212f423bba51c0fecc09dd17
Autor:
Amira Jusovic-Stocanin, Elke Kaemmerer, Hannah Ihle, Angelina Autsch, Sandra Kleemann, Juliane Sanft, Michael Hubig, Gita Mall, Nikolaus Gassler
Publikováno v:
Diseases, Vol 12, Iss 10, p 241 (2024)
In systemic hyper-inflammation, as in severe COVID-19 disease, there are pronounced disorders of the hematological and lymphatic systems with prognostically relevant hemophagocytosis of the bone marrow. The current work aimed to address the importanc
Externí odkaz:
https://doaj.org/article/2faa2ad107ed44ee8a77ae9c2dbe1297
Autor:
Wenfang Gui, Mikal Jacob Hole, Antonio Molinaro, Karolina Edlund, Kristin K. Jørgensen, Huan Su, Brigitte Begher-Tibbe, Nikolaus Gaßler, Carolin V. Schneider, Uthayakumar Muthukumarasamy, Antje Mohs, Lijun Liao, Julius Jaeger, Christian J. Mertens, Ina Bergheim, Till Strowig, Jan G. Hengstler, Johannes R. Hov, Hanns-Ulrich Marschall, Christian Trautwein, Kai Markus Schneider
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by chronic inflammation and progressive fibrosis of the biliary tree. The majority of PSC patients suffer from concomitant inflammatory bowel disease (
Externí odkaz:
https://doaj.org/article/822db6e3defc4196a740ad1cdce3eff7
Autor:
Jessica Hoff, Ling Xiong, Tobias Kammann, Sophie Neugebauer, Julia M. Micheel, Nikolaus Gaßler, Michael Bauer, Adrian T. Press
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-16 (2023)
Abstract Necroptosis facilitates cell death in a controlled manner and is employed by many cell types following injury. It plays a significant role in various liver diseases, albeit the cell-type-specific regulation of necroptosis in the liver and es
Externí odkaz:
https://doaj.org/article/fafdec10994e41eb93f99e613ef4c196
Autor:
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Peixin Dong, Nikolaus Gassler, Mohammad Taheri, Aria Baniahmad, Nader Akbari Dilmaghani
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-69 (2022)
Abstract The Cyclin-dependent kinase (CDK) class of serine/threonine kinases has crucial roles in the regulation of cell cycle transition and is mainly involved in the pathogenesis of cancers. The expression of CDKs is controlled by a complex regulat
Externí odkaz:
https://doaj.org/article/0a0c9af078f04b028b0f715b2d066b3a
Autor:
Dustin Beyer, Jessica Hoff, Oliver Sommerfeld, Alexander Zipprich, Nikolaus Gaßler, Adrian T. Press
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-15 (2022)
Abstract Liver failure is a life-threatening complication of infections restricting the host's response to infection. The pivotal role of the liver in metabolic, synthetic, and immunological pathways enforces limits the host's ability to control the
Externí odkaz:
https://doaj.org/article/659ad0f61403493d8c1ebb4bb4bf1990
Autor:
Tobias Hoffmann, Peter Oelzner, Ulf Teichgräber, Marcus Franz, Nikolaus Gaßler, Claus Kroegel, Gunter Wolf, Alexander Pfeil
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
Lung involvement is the most common and serious organ manifestation in patients with inflammatory rheumatic disease (IRD). The type of pulmonary involvement can differ, but the most frequent is interstitial lung disease (ILD). The clinical manifestat
Externí odkaz:
https://doaj.org/article/268356ae887549da99f775aea235d14d
Autor:
Adrian T Press, Petra Babic, Bianca Hoffmann, Tina Müller, Wanling Foo, Walter Hauswald, Jovana Benecke, Martina Beretta, Zoltán Cseresnyés, Stephanie Hoeppener, Ivo Nischang, Sina M Coldewey, Markus H Gräler, Reinhard Bauer, Falk Gonnert, Nikolaus Gaßler, Reinhard Wetzker, Marc Thilo Figge, Ulrich S Schubert, Michael Bauer
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp 1-17 (2021)
Abstract Jaundice, the clinical hallmark of infection‐associated liver dysfunction, reflects altered membrane organization of the canalicular pole of hepatocytes and portends poor outcomes. Mice lacking phosphoinositide 3‐kinase‐γ (PI3Kγ) are
Externí odkaz:
https://doaj.org/article/0fad10ab812d436c8a511f93c2eb66d8
Autor:
Tobias Hoffmann, Nikolaus Gassler, Ulf Teichgräber, Tim Sandhaus, Peter Oelzner, Gunter Wolf, Alexander Pfeil
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 2, Pp 61-62 (2023)
Externí odkaz:
https://doaj.org/article/00456de6ecc44bf8acb117b6904cd803
Autor:
Andreas Dittberner, Rafat Ziadat, Franziska Hoffmann, David Pertzborn, Nikolaus Gassler, Orlando Guntinas-Lichius
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundWhite-light endoscopy and microscopy combined with histological analysis is currently the mainstay for intraprocedural tissue diagnosis during panendoscopy for head and neck cancer. However, taking biopsies leads to selection bias, ex vivo
Externí odkaz:
https://doaj.org/article/cfe991b8225f40c9864bca8d401de563