Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nikolas R, Burton"'
Autor:
Nikolas R. Burton, Keriann M. Backus
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Mapping the ligandability or potential druggability of all proteins in the human proteome is a central goal of mass spectrometry-based covalent chemoproteomics. Achieving this ambitious objective requires high throughput and high coverage sa
Externí odkaz:
https://doaj.org/article/5c9a1665fc4442f3852c0596e4439907
Autor:
Tianyang Yan, Andrew B. Palmer, Daniel J. Geiszler, Daniel A. Polasky, Lisa M. Boatner, Nikolas R. Burton, Ernest Armenta, Alexey I. Nesvizhskii, Keriann M. Backus
Publikováno v:
Analytical Chemistry. 94:3800-3810
Mass spectrometry-based chemoproteomics has enabled functional analysis and small molecule screening at thousands of cysteine residues in parallel. Widely adopted chemoproteomic sample preparation workflows rely on the use of pan cysteine-reactive pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dadd80a4e1f19030a0ef65033e33ca8
https://doi.org/10.1021/acs.analchem.1c04402
https://doi.org/10.1021/acs.analchem.1c04402
Autor:
Roger Machín Rivera, Nikolas R. Burton, Luke D. Call, Marshall A. Tomat, Vincent N. G. Lindsay
Publikováno v:
Org Lett
Pericyclic processes such as [3,3]-sigmatropic rearrangements leading to the rapid generation of molecular complexity constitute highly valuable tools in organic synthesis. Herein, we report the formation of particularly hindered tertiary alcohols vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc66087fd59f720f055892074a85d9f2
https://europepmc.org/articles/PMC9502203/
https://europepmc.org/articles/PMC9502203/
Autor:
Jason Wu, Allison S. Hacker, Ohyun Kwon, Nikolas R Burton, Jason C. Quintana, Andrew J. Smaligo, Ruoxi Wang, Changmin Xie, Aslam C. Shaikh
Publikováno v:
Angewandte Chemie International Edition. 59:1211-1215
Reported herein is a one-pot protocol for the oxodealkenylative introduction of carbonyl functionalities into terpenes and terpene-derived compounds. This transformation proceeds by Criegee ozonolysis of an alkene, reductive cleavage of the resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b66413c41c6145e8bbd101a94a118dc
https://doi.org/10.1002/anie.201913201
https://doi.org/10.1002/anie.201913201
Autor:
Jian Cao, Lisa M Boatner, Keriann M. Backus, Heta S Desai, Ernest Armenta, Nikolas R Burton, Neil J. Chan, Jose Omar Castellon
Publikováno v:
Anal Chem
Mass-spectrometry-based chemoproteomics has enabled the rapid and proteome-wide discovery of functional and potentially 'druggable' hotspots in proteins. While numerous transformations are now available, chemoproteomic studies still rely overwhelming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fb40882db17d2e87f23da2924a4618
https://europepmc.org/articles/PMC8849040/
https://europepmc.org/articles/PMC8849040/
Autor:
Andrew J, Smaligo, Jason, Wu, Nikolas R, Burton, Allison S, Hacker, Aslam C, Shaikh, Jason C, Quintana, Ruoxi, Wang, Changmin, Xie, Ohyun, Kwon
Publikováno v:
Angew Chem Int Ed Engl
Reported herein is a one-pot protocol for the oxodealkenylative introduction of carbonyl functionalities into terpenes and terpene-derived compounds. This transformation proceeds by Criegee ozonolysis of an alkene, reductive cleavage of the resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd569a9cef81545f487d0bb50df32c7f
https://pubmed.ncbi.nlm.nih.gov/31692203
https://pubmed.ncbi.nlm.nih.gov/31692203
Autor:
Burton, Nikolas R.1,2 (AUTHOR), Backus, Keriann M.1,2,3,4,5,6 (AUTHOR) kbackus@mednet.ucla.edu
Publikováno v:
Communications Chemistry. 4/10/2024, Vol. 7 Issue 1, p1-12. 12p.
Autor:
Smaligo, Andrew J.1 (AUTHOR), Wu, Jason1 (AUTHOR), Burton, Nikolas R.1 (AUTHOR), Hacker, Allison S.1 (AUTHOR), Shaikh, Aslam C.1 (AUTHOR), Quintana, Jason C.1 (AUTHOR), Wang, Ruoxi1 (AUTHOR), Xie, Changmin1 (AUTHOR), Kwon, Ohyun1 (AUTHOR) ohyun@chem.ucla.edu
Publikováno v:
Angewandte Chemie. Jan2020, Vol. 132 Issue 3, p1227-1231. 5p.
Publikováno v:
Organic & Biomolecular Chemistry; 9/28/2021, Vol. 19 Issue 36, p7729-7735, 7p
Publikováno v:
Organic & Biomolecular Chemistry; 9/28/2021, Vol. 19 Issue 36, p7792-7809, 18p