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of 10
pro vyhledávání: '"Nikolas Nikolaou"'
Autor:
Shaakir Salam, Sara Tacconelli, Bradley N. Smith, Jacqueline C. Mitchell, Elizabeth Glennon, Nikolas Nikolaou, Corinne Houart, Caroline Vance
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Aberrantly expressed fused in sarcoma (FUS) is a hallmark of FUS-related amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Wildtype FUS localises to synapses and interacts with mitochondrial proteins while mutations have
Externí odkaz:
https://doaj.org/article/0579a38085794fbda811e7a5e4c1c5ce
Publikováno v:
Cell Reports, Vol 5, Iss 3, Pp 582-592 (2013)
A striking feature of the CNS is the precise wiring of its neuronal connections. During vertebrate visual system development, different subtypes of retinal ganglion cells (RGCs) form specific connections with their corresponding synaptic partners. Ho
Externí odkaz:
https://doaj.org/article/bb01cbf53c7f427d852c99fb36ef290b
Autor:
Nikolas Nikolaou, Patricia M. Gordon, Fursham Hamid, Richard Taylor, Joshua Lloyd-Jones, Eugene V. Makeyev, Corinne Houart
Publikováno v:
Current Biology. 32:5099-5115.e8
Regulation of pre-mRNA splicing and polyadenylation plays a profound role in neurons by diversifying the proteome and modulating gene expression in response to physiological cues. Although most of the pre-mRNA processing is thought to occur in the nu
Autor:
Sara Tacconelli, Elizabeth B. Glennon, Corinne Houart, Nikolas Nikolaou, Caroline Vance, Bradley N. Smith, Jacqueline C. Mitchell, Shaakir Salam
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
BackgroundAberrantly expressed fused in sarcoma (FUS) is a hallmark of FUS-related amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Wildtype FUS localises to synapses and interacts with mitochondrial proteins while mutations hav
Autor:
Corinne Houart, Ruth D. Taylor, Patricia M. Gordon, Fursham Hamid, Nikolas Nikolaou, Eugene V. Makeyev
SUMMARYRegulation of pre-mRNA splicing and polyadenylation plays a profound role in neurons by diversifying the proteome and modulating gene expression during development and in response to physiological cues. Although most pre-mRNA processing reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1bb685f857400ef120724d64929c0ad
https://doi.org/10.1101/2020.05.25.097444
https://doi.org/10.1101/2020.05.25.097444
Publikováno v:
Cell Reports, Vol 5, Iss 3, Pp 582-592 (2013)
Cell Reports
Antinucci, P, Nikolaou, N, Meyer, M & Hindges, R 2013, ' Teneurin-3 Specifies Morphological and Functional Connectivity of Retinal Ganglion Cells in the Vertebrate Visual System ', Cell Reports, vol. 5, no. 3, pp. 582-592 . https://doi.org/10.1016/j.celrep.2013.09.045
Cell Reports
Antinucci, P, Nikolaou, N, Meyer, M & Hindges, R 2013, ' Teneurin-3 Specifies Morphological and Functional Connectivity of Retinal Ganglion Cells in the Vertebrate Visual System ', Cell Reports, vol. 5, no. 3, pp. 582-592 . https://doi.org/10.1016/j.celrep.2013.09.045
Summary A striking feature of the CNS is the precise wiring of its neuronal connections. During vertebrate visual system development, different subtypes of retinal ganglion cells (RGCs) form specific connections with their corresponding synaptic part
Publikováno v:
Lowe, A S, Nikolaou, N, Hunter, P R, Thompson, I D & Meyer, M P 2013, ' A Systems-Based Dissection of Retinal Inputs to the Zebrafish Tectum Reveals Different Rules for Different Functional Classes during Development ', Journal of Neuroscience, vol. 33, no. 35, pp. 13946-13956 . https://doi.org/10.1523/JNEUROSCI.1866-13.2013
We have examined the form, diversity, and organization of three functional classes of retinal inputs to the zebrafish optic tectum during development. Our systems-based approach was to analyze data from populations of retinal ganglion cells labeled w
Autor:
Martin P. Meyer, Nikolas Nikolaou
Publikováno v:
Developmental Neurobiology. 72:346-357
The study of nervous system development has been greatly facilitated by recent advances in molecular biology and imaging techniques. These approaches are perfectly suited to young transparent zebrafish where they have allowed direct observation of ne
Autor:
Nikolas Nikolaou, Reinhard W. Köster, David G. Wilkinson, Sebastian S. Gerety, Tomomi Watanabe-Asaka, Martin Distel
Previous studies have identified roles of the modulation of Notch activation by Fringe homologues in boundary formation and in regulating the differentiation of vertebrate thymocytes and Drosophila glial cells. We have investigated the role of Lunati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d977ccfe1a82c3068bf3249192ef17
https://europepmc.org/articles/PMC2709061/
https://europepmc.org/articles/PMC2709061/
Autor:
Nikolas Nikolaou, Martin P. Meyer
Publikováno v:
Current Biology
Summary Visuomotor circuits filter visual information and determine whether or not to engage downstream motor modules to produce behavioral outputs. However, the circuit mechanisms that mediate and link perception of salient stimuli to execution of a