Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nikolas Klein"'
Autor:
Alexander Geppert, Gottfried Heinz, Markus Müller, Markus Zeitlinger, Martin Frossard, Christian Joukhadar, Peter Dittrich, Keso Skhirtladze, Nikolas Klein
Publikováno v:
Journal of Antimicrobial Chemotherapy. 51:1247-1252
The present study was undertaken to investigate the target site penetration properties of fosfomycin, an antibiotic particularly suitable for treatment of soft tissue infections (STIs) in critically ill patients.The study population included nine pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93aa7ae1d8c181bf14491f314f759006
https://doi.org/10.1093/jac/dkg187
https://doi.org/10.1093/jac/dkg187
Autor:
Oswald Wagner, Michael Roden, Christian Bieglmayer, Martin Frossard, Christian Joukhadar, Edith Lackner, Markus Müller, Herbert Langenberger, Harald Herkner, Nikolas Klein
Publikováno v:
European Journal of Clinical Investigation. 33:141-146
BACKGROUND Transcapillary insulin transfer is considered a rate-limiting step in insulin action at supraphysiological insulin concentrations. However, it remains unclear whether this concept also applies for physiological conditions. MATERIALS AND ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa9e94019f151e1d6c8d7c20c763ce4
https://doi.org/10.1046/j.1365-2362.2003.01106.x
https://doi.org/10.1046/j.1365-2362.2003.01106.x
Autor:
Harald Herkner, Nicole Kreischitz, Martin Frossard, Edith Lackner, M.R. Müller, Christian Joukhadar, Nikolas Klein, Markus Müller, Bernhard X. Mayer
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 165:273-276
The majority of bacterial lung infections are localized to the interstitial space fluid, which is therefore an important target site for antimicrobial chemotherapy. Direct measurement of interstitial concentrations of antimicrobial agents in human lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6be9f7d0beffca27a13b7b044c1acaf
https://doi.org/10.1164/ajrccm.165.2.2106082
https://doi.org/10.1164/ajrccm.165.2.2106082
Autor:
Nikolas Klein
Publikováno v:
Gesellschaftsrecht in der Diskussion 2013
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee7a20d990b8966e8155e0d35be583aa
https://doi.org/10.9785/ovs.9783504383961.101
https://doi.org/10.9785/ovs.9783504383961.101
Autor:
Markus Herrmann, Heino Stass, Christian Joukhadar, Edith Lackner, Markus Müller, Nikolas Klein, Eva Riedmüller, Erich Minar, Martin Frossard
Publikováno v:
Clinical Pharmacology & Therapeutics. 70:546-551
Objective Patients with peripheral arterial occlusive disease are prone to soft tissue infections and frequently require antibiotics. To date, however, it is not known whether improvement of arterial blood flow by angioplasty of stenosis increases an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5676bfe771dc47115fb145b21704643
https://doi.org/10.1016/s0009-9236(01)74143-4
https://doi.org/10.1016/s0009-9236(01)74143-4
Autor:
Peter Siostrzonek, Markus Müller, Bernhard X. Mayer, Hans Georg Eichler, Martin Brunner, Nikolas Klein, Martin Frossard, Christian Joukhadar
Publikováno v:
Critical Care Medicine. 29:385-391
Current guidelines for adjusting antimicrobial therapy regimens commonly are based on drug concentrations measured in plasma. In septic patients, however, the interstitial space of soft tissues in addition to the central compartment represents the ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1c0ba1cc9373215f6f247ca4eeaea2
https://doi.org/10.1097/00003246-200102000-00030
https://doi.org/10.1097/00003246-200102000-00030
Autor:
Gerhard Fuhrmann, Georg Rosenberger, Michael Grusch, Georg Krupitza, Johannes Hofmann, Nikolas Klein
Publikováno v:
Mutation Research/Reviews in Mutation Research. 437:205-217
Over-expression of the transcription factor c-Myc immortalizes primary cells and transforms in co-operation with activated ras. Therefore, c-myc is considered a proto-oncogene. Since its discovery c-Myc has been shown to render cells growth factor in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbfd79b336bb2d4af90349cdb382552
https://doi.org/10.1016/s1383-5742(99)00084-8
https://doi.org/10.1016/s1383-5742(99)00084-8
Autor:
Markus Müller, A. Donner, M.J. Barbanoj, Marta Valle, I. Izquierdo, U. Herranz, Nikolas Klein, Hans-Georg Eichler, Martin Brunner
Publikováno v:
European journal of clinical pharmacology. 61(2)
Triflusal has been shown to exert neuroprotective effects by downregulating molecules considered responsible for the development of Alzheimer's disease (AD). The aim of this study was to develop a population pharmacokinetic model to characterize plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97a36313e95efb00fbe6c0492c1534d
https://pubmed.ncbi.nlm.nih.gov/15711832
https://pubmed.ncbi.nlm.nih.gov/15711832
Publikováno v:
Textbook of Biological Psychiatry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de517e1bf49d4bb021a35bb8def38319
https://doi.org/10.1002/0471468975.ch6
https://doi.org/10.1002/0471468975.ch6
Autor:
Bernhard X. Mayer, Gottfried Heinz, Nikolas Klein, Nicole Kreischitz, Peter Palkovits, Christian Joukhadar, Markus Müller, Georg Delle-Karth
Publikováno v:
Critical care medicine. 30(7)
Broad initial antibiotic treatment is crucial for patients experiencing septic shock or severe sepsis. Fourth-generation beta-lactam antibiotics, such as cefpirome, are frequently favored in these conditions because of their low toxicity and wide ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc34322d2c981f14dbca3abe952b143
https://pubmed.ncbi.nlm.nih.gov/12130965
https://pubmed.ncbi.nlm.nih.gov/12130965