Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Nikolas J Hodges"'
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30587 (2012)
Cytoglobin is an intracellular globin of unknown function that is expressed mostly in cells of a myofibroblast lineage. Possible functions of cytoglobin include buffering of intracellular oxygen and detoxification of reactive oxygen species. Previous
Externí odkaz:
https://doaj.org/article/272c7280f8c84174a79bf865ce3ee2aa
Autor:
Lorna S. Thorne, Garret Rochford, Timothy D. Williams, Andrew D. Southam, Giovanny Rodriguez-Blanco, Warwick B. Dunn, Nikolas J. Hodges
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Cytoglobin is important in the progression of oral squamous cell carcinoma but the molecular and cellular basis remain to be elucidated. In the current study, we develop a new cell model to study the function of cytoglobin in oral squamous c
Externí odkaz:
https://doaj.org/article/59c7ba7ed6054be7b34453142d43f65a
Autor:
Abiola N. Dosumu, Sunil Claire, Luke S. Watson, Patricia M. Girio, Shani A. M. Osborne, Zoe Pikramenou, Nikolas J. Hodges
Publikováno v:
JACS Au, Vol 1, Iss 2, Pp 174-186 (2021)
Externí odkaz:
https://doaj.org/article/ec960953a4b54a6ab2c389c0666193b3
Autor:
Asier R. Muguruza, Alessandro di Maio, Nikolas J. Hodges, Jessica M. A. Blair, Zoe Pikramenou
Publikováno v:
Nanoscale Advances. 5:2453-2461
Silica nanoparticles decorated with aminocarboxylate ligands are novel vehicles to deliver antibiotics which are otherwise not able to penetrate the bacteria membrane and can also include agents for tracking and imaging.
Publikováno v:
Heterocyclic Communications. 28:11-17
This research investigated the general high-throughput synthetic protocol for the accelerated synthesis of functionalized trifluoromethylpyrazolopyrimidines 3 and N-(5-cyano-3-methyl-1-phenyl-1H-pyrazol-4-yl) benzamide 4 from aminocyanopyrazole 1 pre
Autor:
Maryam Naghynajadfard, Nikolas J Hodges, Adam Towler, Amanda J Lee, Joanna Norman, Ryan Doran, Rhiannon M David, Anne E Pheasant, Jerry Marsden, James K Chipman
Cutaneous Malignant Melanoma (CMM) is a life threatening disease whose incidence and mortality rates have risen rapidly in the White Caucasian population in recent decades. The aim of the current study was to investigate the association between polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e315d702748861cf4a7bf1a1a7ec523
https://doi.org/10.1101/2022.12.19.22283655
https://doi.org/10.1101/2022.12.19.22283655
Autor:
Brandon A. Coke, Emma L. Shepherd, Nikolas J. Hodges, Kyriaki Chatzi, Timothy Schulz-utermoehl, Nicholas J. Coltman, Patricia F. Lalor
Publikováno v:
Toxicology Letters. 345:34-45
HepG2 cells continue to be a valuable tool in early drug discovery and pharmaceutical development. In the current study we develop a 3D in vitro liver model, using HepG2/C3A cells that is predictive of human genotoxic exposure. HepG2/C3A cells cultur
Autor:
Garret Rochford, Rameeza Basar, Rose Dhiman, Djeren Simitdjioglu, Lorna S Thorne, Lakis Liloglou, Janet M. Risk, Nikolas J Hodges
Cytoglobin has been implicated in a range of pathological conditions including fibrosis and cancer, where cytoglobin expression is linked to hypoxia- and drug-resistance. One disease where there is evidence of a role for cytoglobin is head and neck s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df064cfa94c576f2813dd90630d053bf
Autor:
Patricia M. Girio, Shani A. M. Osborne, Luke S. Watson, Sunil Claire, Nikolas J. Hodges, Zoe Pikramenou, Abiola N. Dosumu
Publikováno v:
Jacs Au
JACS Au, Vol 1, Iss 2, Pp 174-186 (2021)
JACS Au, Vol 1, Iss 2, Pp 174-186 (2021)
Optical microscopy techniques are ideal for live cell imaging for real-time nanoparticle tracking of nanoparticle localization. However, the quantification of nanoparticle uptake is usually evaluated by analytical methods that require cell isolation.
Autor:
Nikolas J. Hodges, Tim D. Williams, Garret Rochford, Lorna Susan Thorne, Andrew D. Southam, Giovanny Rodriguez-Blanco, Warwick B. Dunn
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Cytoglobin is important in the progression of oral squamous cell carcinoma but the molecular and cellular basis remain to be elucidated. In the current study, we develop a new cell model to study the function of cytoglobin in oral squamous carcinoma