Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nikolaos Mitrousis"'
Autor:
Haitao Liu, Sayan Ghosh, Tanuja Vaidya, Sridhar Bammidi, Chao Huang, Peng Shang, Archana Padmanabhan Nair, Olivia Chowdhury, Nadezda A. Stepicheva, Anastasia Strizhakova, Stacey Hose, Nikolaos Mitrousis, Santosh Gopikrishna Gadde, Thirumalesh MB, Pamela Strassburger, Gabriella Widmer, Eleonora M. Lad, Patrice E. Fort, José-Alain Sahel, J. Samuel Zigler Jr., Swaminathan Sethu, Peter D. Westenskow, Alan D. Proia, Akrit Sodhi, Arkasubhra Ghosh, Derrick Feenstra, Debasish Sinha
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
Diabetic retinopathy (DR) is a leading cause of blindness in working-age adults and remains an important public health issue worldwide. Here we demonstrate that the expression of stimulator of interferon genes (STING) is increased in patients with DR
Externí odkaz:
https://doaj.org/article/b18fbfa1ae7541e5a0a6f27bd00d5aed
Autor:
Lisa R. Volpatti, Rachel P. Wallace, Shijie Cao, Michal M. Raczy, Ruyi Wang, Laura T. Gray, Aaron T. Alpar, Priscilla S. Briquez, Nikolaos Mitrousis, Tiffany M. Marchell, Maria Stella Sasso, Mindy Nguyen, Aslan Mansurov, Erica Budina, Ani Solanki, Elyse A. Watkins, Mathew R. Schnorenberg, Andrew C. Tremain, Joseph W. Reda, Vlad Nicolaescu, Kevin Furlong, Steve Dvorkin, Shann S. Yu, Balaji Manicassamy, James L. LaBelle, Matthew V. Tirrell, Glenn Randall, Marcin Kwissa, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
Externí odkaz:
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Autor:
Laura T. Gray, Glenn Randall, Mindy Nguyen, Matthew Tirrell, Marcin Kwissa, Steve Dvorkin, Aaron T. Alpar, Balaji Manicassamy, Jeffrey A. Hubbell, Nikolaos Mitrousis, Elyse A. Watkins, James L. LaBelle, Tiffany M. Marchell, Erica Budina, Shann S. Yu, Shijie Cao, Ruyi Wang, Rachel P. Wallace, Michal M. Raczy, Mathew R. Schnorenberg, Kevin Furlong, Vlad Nicolaescu, Lisa R. Volpatti, Andrew C Tremain, Melody A. Swartz, Joseph W. Reda, Aslan Mansurov, Maria Stella Sasso, Priscilla S. Briquez, Ani Solanki
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Central Science
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Central Science
The COVID-19 pandemic underscores the need for rapid, safe, and effective vaccines. In contrast to some traditional vaccines, nanoparticle-based subunit vaccines are particularly efficient in trafficking antigens to lymph nodes, where they induce pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eb21cfa353bc8b2d6928782bffd622
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Autor:
Tiffany M. Marchell, Nikolaos Mitrousis, Ruyi Wang, Laura T. Gray, Glenn Randall, Melody A. Swartz, Marcin Kwissa, Rachel P. Wallace, Kevin Furlong, Vlad Nicolaescu, Michal M. Raczy, Mindy Nguyen, Elyse A. Watkins, Balaji Manicassamy, Andrew C Tremain, D. Scott Wilson, Lisa R. Volpatti, Ani Solanki, Steve Dvorkin, Maria Stella Sasso, Shijie Cao, Erica Budina, Aaron T. Alpar, Jeffrey A. Hubbell, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez, Shann S. Yu
The SARS-CoV-2 virus has caused an unprecedented global crisis, and curtailing its spread requires an effective vaccine which elicits a diverse and robust immune response. We have previously shown that vaccines made of a polymeric glyco-adjuvant conj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::609dc88b5ac6a29a8652cb34dab4d818
https://doi.org/10.1101/2021.05.20.445060
https://doi.org/10.1101/2021.05.20.445060
Autor:
Ani Solanki, Marcin Kwissa, Andrew C Tremain, Vlad Nicolaescu, Aaron T. Alpar, Nikolaos Mitrousis, Melody A. Swartz, Lisa R. Volpatti, Shann S. Yu, Rachel P. Wallace, Matthew Tirrell, Ruyi Wang, Elyse A. Watkins, Maria Stella Sasso, Tiffany M. Marchell, Balaji Manicassamy, Michal M. Raczy, Shijie Cao, Steve Dvorkin, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez, Kevin Furlong, Mathew R. Schnorenberg, Glenn Randall, Erica Budina, Mindy Nguyen, Laura T. Gray, Jeffrey A. Hubbell, James L. LaBelle
A diverse portfolio of SARS-CoV-2 vaccine candidates is needed to combat the evolving COVID-19 pandemic. Here, we developed a subunit nanovaccine by conjugating SARS-CoV-2 Spike protein receptor binding domain (RBD) to the surface of oxidation-sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29e4a1f213b1a04920be54ae8e85047
https://doi.org/10.1101/2021.04.08.438884
https://doi.org/10.1101/2021.04.08.438884
Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas
Autor:
Nikolaos Mitrousis, Priscilla S. Briquez, Yue Wang, Maria Stella Sasso, Melody A. Swartz, Sylvie Hauert, Jeffrey A. Hubbell, Jun Ishihara
Publikováno v:
Science Advances
New approach for immune cell recruitment in therapeutic anticancer vaccines drives antigenically broad and long-lasting immunity.
In melanoma, the induction of lymphatic growth (lymphangiogenesis) has long been correlated with metastasis and poo
In melanoma, the induction of lymphatic growth (lymphangiogenesis) has long been correlated with metastasis and poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1b7b84160992e3ce2d2600128a469a
https://doi.org/10.1126/sciadv.abe4362
https://doi.org/10.1126/sciadv.abe4362
Autor:
Margaret T. Ho, Andras Nagy, Nikolaos Mitrousis, Yves Sauve, Molly S. Shoichet, Derek van der Kooy, Sabiha Hacibekiroglu
Publikováno v:
Biomaterials. 257
We demonstrate a novel approach to reverse advanced stages of blindness using hydrogel-mediated delivery of retinal pigmented epithelium (RPE) and photoreceptors directly to the degenerated retina of blind mice. With sodium iodate (NaIO3) injections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a5ca617de6cddf62502f6f8e42381f
https://pubmed.ncbi.nlm.nih.gov/32791386
https://pubmed.ncbi.nlm.nih.gov/32791386
Publikováno v:
Nature Reviews Materials. 3:441-456
Cell transplantation holds immense potential for reversing diseases that are currently incurable and for regenerating tissues. However, poor cell survival, cell aggregation and lack of cell integration into the host tissue constitute major challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b22e6a37fe96c652510882214d7f3379
https://doi.org/10.1038/s41578-018-0057-0
https://doi.org/10.1038/s41578-018-0057-0
Autor:
Ruyi Wang, Nikolaos Mitrousis, Melody A. Swartz, Kevin Furlong, D. Scott Wilson, Vlad Nicolaescu, Elyse A. Watkins, Tiffany M. Marchell, Lisa R. Volpatti, Balaji Manicassamy, Andrew C Tremain, Glenn Randall, Rachel P. Wallace, Ani Solanki, Laura T. Gray, Steve Dvorkin, Marcin Kwissa, Maria Stella Sasso, Mindy Nguyen, Aaron T. Alpar, Michal M. Raczy, Jeffrey A. Hubbell, Erica Budina, Shijie Cao, Shann S. Yu, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez
Publikováno v:
Biomaterials
The SARS-CoV-2 virus has caused an unprecedented global crisis, and curtailing its spread requires an effective vaccine which elicits a diverse and robust immune response. We have previously shown that vaccines made of a polymeric glyco-adjuvant conj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b93d0c83332f519748f85280205edd
http://europepmc.org/articles/PMC8482845
http://europepmc.org/articles/PMC8482845
Autor:
Jun Ishihara, Nikolaos Mitrousis, Melody A. Swartz, Maria Stella Sasso, Priscilla S. Briquez, Yue Wang, Sylvie Hauert, Jeffrey A. Hubbell
Publikováno v:
Cancer Research. 80:1072-1072
We recently demonstrated that the growth of tumor-associated lymphatic vessels (lymphangiogenesis) promotes immune infiltration in melanoma (Lund et al. 2016) and increases T cell activation following immunotherapy, resulting in strongly enhanced the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74419bef2ac25812a7c4169fec91e1c1
https://doi.org/10.1158/1538-7445.am2020-1072
https://doi.org/10.1158/1538-7445.am2020-1072