Zobrazeno 1 - 10
of 414
pro vyhledávání: '"Nikolaos G. Frangogiannis"'
Autor:
Nikolaos Frangogiannis
Publikováno v:
Discoveries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720b8014e4a74dd51582370f16e23ea4
https://pubmed.ncbi.nlm.nih.gov/32309549
https://pubmed.ncbi.nlm.nih.gov/32309549
Autor:
Ruoshui Li, Bijun Chen, Akihiko Kubota, Anis Hanna, Claudio Humeres, Silvia C. Hernandez, Yang Liu, Richard Ma, Izabela Tuleta, Shuaibo Huang, Harikrishnan Venugopal, Fenglan Zhu, Kai Su, Jun Li, Jinghang Zhang, Deyou Zheng, Nikolaos G. Frangogiannis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Macrophages sense changes in the extracellular matrix environment through the integrins and play a central role in regulation of the reparative response after myocardial infarction. Here we show that macrophage integrin α5 protects the infa
Externí odkaz:
https://doaj.org/article/2c80b06b17ca43dea72a0bd195b86518
Publikováno v:
Discoveries (Craiova, Romania) [Discoveries (Craiova)] 2014 Jun 30; Vol. 2 (2), pp. e20. Date of Electronic Publication: 2014 Jun 30.
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 6 (2023)
Background Interstitial and perivascular fibrosis may contribute to diabetes‐associated heart failure. Pericytes can convert to fibroblasts under conditions of stress and have been implicated in the pathogenesis of fibrotic diseases. We hypothesize
Externí odkaz:
https://doaj.org/article/8238c6a255b64184bc43b948e8ed2392
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Reliable tools for macrophage identification in mouse tissues are critical for studies investigating inflammatory and reparative responses. Transgenic reporter mice and anti-macrophage antibodies have been used as “specific pan-macrophage
Externí odkaz:
https://doaj.org/article/3b7ea66225014cfbbd3e63a02dbf7432
Autor:
Claudio Humeres, Arti V. Shinde, Anis Hanna, Linda Alex, Silvia C. Hernández, Ruoshui Li, Bijun Chen, Simon J. Conway, Nikolaos G. Frangogiannis
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
Repair of the infarcted heart requires TGF-β/Smad3 signaling in cardiac myofibroblasts. However, TGF-β–driven myofibroblast activation needs to be tightly regulated in order to prevent excessive fibrosis and adverse remodeling that may precipitat
Externí odkaz:
https://doaj.org/article/cf5b1c6e35dd4f71ae1a816c353b45b6
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 1 (2022)
Background In the myocardium, pericytes are often confused with other interstitial cell types, such as fibroblasts. The lack of well‐characterized and specific tools for identification, lineage tracing, and conditional targeting of myocardial peric
Externí odkaz:
https://doaj.org/article/9870d3e2de4e41c8a3451430807cde27
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 449-467 (2019)
Summary: Expansion and activation of fibroblasts following cardiac injury is important for repair but may also contribute to fibrosis, remodeling, and dysfunction. The authors discuss the dynamic alterations of fibroblasts in failing and remodeling m
Externí odkaz:
https://doaj.org/article/d5df0791839442adaecce125cd72ef3d
Autor:
Nikolaos G. Frangogiannis
Publikováno v:
JACC: Basic to Translational Science. 8:497-500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae07f6ec03f6af16e9d3ad889b38bae2
https://doi.org/10.1016/j.jacbts.2023.02.004
https://doi.org/10.1016/j.jacbts.2023.02.004
Publikováno v:
Cells, Vol 11, Iss 9, p 1386 (2022)
The adult mammalian heart contains abundant interstitial and perivascular fibroblasts that expand following injury and play a reparative role but also contribute to maladaptive fibrotic remodeling. Following myocardial infarction, cardiac fibroblasts
Externí odkaz:
https://doaj.org/article/9f9214ad172742e092a66b7c72c8782c