Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Nikolaos E. Labrou"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Multidrug-resistant (MDR) bacteria have become a growing threat to public health. The gram-positive Enterococcus faecium is classified by WHO as a high-priority pathogen among the global priority list of antibiotic-resistant bacteria. Peptid
Externí odkaz:
https://doaj.org/article/5cd4d25526844aaeafcca8248ae05f43
Autor:
Steliana Tsouri, Evanthia Tselo, Georgios E. Premetis, Veronika Furlan, Panagiota D. Pantiora, Barbara Mavroidi, Dimitris Matiadis, Maria Pelecanou, Anastassios C. Papageorgiou, Urban Bren, Marina Sagnou, Nikolaos E. Labrou
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 365 (2024)
Human glutathione transferase A4-4 (hGSTA4-4) displays high catalytic efficiency towards 4-hydroxyalkenals and other cytotoxic and mutagenic products of radical reactions and lipid peroxidation. Its role as a target for the chemosensitization of canc
Externí odkaz:
https://doaj.org/article/1c39e881fdbf4dc7948c349b505a5aa6
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 85 (2023)
Fosfomycin-resistance proteins (FosAs) are dimeric metal-dependent glutathione transferases that conjugate the antibiotic fosfomycin (Fos) to the tripeptide glutathione (γ-Glu-Cys-Gly, GSH), rendering it inactive. In the present study, we reported a
Externí odkaz:
https://doaj.org/article/f8e1b8f944d84112a4fc553dc1ca0951
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 41 (2023)
Glutathione peroxidases (GPXs) are antioxidant selenoenzymes, which catalyze the reduction of hydroperoxides via glutathione (GSH), providing protection to cells against oxidative stress metabolites. The present study aims to create an efficient semi
Externí odkaz:
https://doaj.org/article/83015a6ac6604e96a1606d0e7bb110ac
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/5a12817b0c0b48dda2ae5f8a3e80dc13
Autor:
Alexandros Mavrommatis, Eleni Tsiplakou, Anastasia Zerva, Panagiota D. Pantiora, Nikolaos D. Georgakis, Georgia P. Tsintzou, Panagiotis Madesis, Nikolaos E. Labrou
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1882 (2023)
Microalgae are a renewable and sustainable source of bioactive compounds, such as essential amino acids, polyunsaturated fatty acids, and antioxidant compounds, that have been documented to have beneficial effects on nutrition and health. Among these
Externí odkaz:
https://doaj.org/article/76220612fc584c2692104dd0f58f9859
Autor:
Nikolaos D. Georgakis, Elisavet Ioannou, Marianna Chatzikonstantinou, Marián Merino, Evangelia G. Chronopoulou, José Luis Mullor, Panagiotis Madesis, Nikolaos E. Labrou
Publikováno v:
Cosmetics, Vol 10, Iss 3, p 75 (2023)
In the present study, selected cosmeceutical properties of aqueous extracts from the microalgae strain Trachydiscus minutus were assessed and compared with those obtained using three widely used Chlorella strains (C. vulgaris, C. sorokiniana, and C.
Externí odkaz:
https://doaj.org/article/3c3e44bd975d4cedaae2b33c88c42970
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8523 (2023)
The emergence of multidrug-resistant (MDR) bacteria has risen rapidly, leading to a great threat to global public health. A promising solution to this problem is the exploitation of phage endolysins. In the present study, a putative N-acetylmuramoyl-
Externí odkaz:
https://doaj.org/article/cb884e04ca3640408f6ec65ed044ed21
Autor:
Oleksii Kupreienko, Fotini Pouliou, Konstantinos Konstandinidis, Irene Axarli, Eleni Douni, Anastassios C. Papageorgiou, Nikolaos E. Labrou
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 613 (2023)
Multidrug resistance is a significant barrier that makes anticancer therapies less effective. Glutathione transferases (GSTs) are involved in multidrug resistance mechanisms and play a significant part in the metabolism of alkylating anticancer drugs
Externí odkaz:
https://doaj.org/article/defe8b6ca8eb44d99a2d53aac5353659
Autor:
Evangelia G. Chronopoulou, Lana Mutabdzija, Nirmal Poudel, Anastassios C. Papageorgiou, Nikolaos E. Labrou
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3700 (2023)
Glutathione transferases (GSTs) are promiscuous enzymes whose main function is the detoxification of electrophilic compounds. These enzymes are characterized by structural modularity that underpins their exploitation as dynamic scaffolds for engineer
Externí odkaz:
https://doaj.org/article/7128a81077b842ddb813948c8beedba6