Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nikolaos Dimitrakakis"'
Autor:
Kwasi Adu-Berchie, Joshua M. Brockman, Yutong Liu, Tania W. To, David K. Y. Zhang, Alexander J. Najibi, Yoav Binenbaum, Alexander Stafford, Nikolaos Dimitrakakis, Miguel C. Sobral, Maxence O. Dellacherie, David J. Mooney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Although adoptive T cell therapy provides the T cell pool needed for immediate tumor debulking, the infused T cells generally have a narrow repertoire for antigen recognition and limited ability for long-term protection. Here, we present a h
Externí odkaz:
https://doaj.org/article/c82858dc6c3249e0bed06dcad9fd4919
Autor:
Mark Cartwright, Martin Rottman, Nathan I. Shapiro, Benjamin Seiler, Patrick Lombardo, Nazita Gamini, Julie Tomolonis, Alexander L. Watters, Anna Waterhouse, Dan Leslie, Dana Bolgen, Amanda Graveline, Joo H. Kang, Tohid Didar, Nikolaos Dimitrakakis, David Cartwright, Michael Super, Donald E. Ingber
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 217-227 (2016)
Background: Blood cultures, and molecular diagnostic tests that directly detect pathogen DNA in blood, fail to detect bloodstream infections in most infected patients. Thus, there is a need for a rapid test that can diagnose the presence of infection
Externí odkaz:
https://doaj.org/article/b480f6acc7b148be903892a421baa371
Autor:
Nikolaos Dimitrakakis, Anna Waterhouse, Shanda Lightbown, Daniel C Leslie, Amanda Jiang, Dana E Bolgen, Kayla Lightbown, Kelly Cascio, Gabriela Aviles, Elizabeth Pollack, Sam Jurek, Kathryn Donovan, Julia B Hicks-Berthet, Kazuo Imaizumi, Michael Super, Donald E Ingber, Arthur Nedder
Publikováno v:
J Am Assoc Lab Anim Sci
Swine are widely used in biomedical research, translational research, xenotransplantation, and agriculture. For these uses, physiologic reference intervals are extremely important for assessing the health status of the swine and diagnosing disease. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aeda1510a342e2860e0061c41d591ea
https://doi.org/10.30802/aalas-jaalas-21-000014
https://doi.org/10.30802/aalas-jaalas-21-000014
Autor:
Morgan A. Burt, Titilola D. Kalejaiye, Rohan Bhattacharya, Nikolaos Dimitrakakis, Samira Musah
Publikováno v:
ACS Chemical Biology. 17:3341-3351
The most severe forms of kidney diseases are often associated with irreversible damage to the glomerular podocytes, the highly specialized epithelial cells that encase glomerular capillaries and regulate the removal of toxins and waste from the blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e0359c6d72a759560ebbf84b479671
https://doi.org/10.1021/acschembio.1c00678
https://doi.org/10.1021/acschembio.1c00678
Autor:
Hamza Ijaz, Frank R. Urena, Des White, Chyenne D. Yeager, David J. Mooney, Vasanth Chandrasekhar, Alexander G. Stafford, Justin M. Scott, Benjamin T. Seiler, Amanda R. Graveline, Edward J. Doherty, Fernanda Langellotto, Mark Cartwright, Shanda L. Lightbown, Aileen W. Li, Caitlin L. Horgan, Mohan Karkada, Donald E. Ingber, Collin Leese-Thompson, Michael Super, Sami A. Rifai, Maxence O. Dellacherie, Nikolaos Dimitrakakis, Kayla R. Lightbown, Amanda R. Jiang
Publikováno v:
Nature Biomedical Engineering. 6:8-18
Most bacterial vaccines work for a subset of bacterial strains or require the modification of the antigen or isolation of the pathogen before vaccine development. Here we report injectable biomaterial vaccines that trigger potent humoral and T-cell r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f25a46b11b58f1a23c029f6b1447a5
https://doi.org/10.1038/s41551-021-00756-3
https://doi.org/10.1038/s41551-021-00756-3
Autor:
Gilles Berger, Erik H. Knelson, Jorge L. Jimenez-Macias, Michal O. Nowicki, Saemi Han, Eleni Panagioti, Patrick H. Lizotte, Kwasi Adu-Berchie, Alexander Stafford, Nikolaos Dimitrakakis, Lanlan Zhou, E. Antonio Chiocca, David J. Mooney, David A. Barbie, Sean E. Lawler
Immunotherapy has had a tremendous impact on cancer treatment in the past decade, with hitherto unseen responses at advanced and metastatic stages of the disease. However, the aggressive brain tumor glioblastoma (GBM) is highly immunosuppressive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663f56c8b95a09a68adec095017e5059
https://doi.org/10.1101/2022.02.28.481908
https://doi.org/10.1101/2022.02.28.481908
Autor:
Maxence O. Dellacherie, Sarai Bardales, David J. Mooney, Benjamin T. Seiler, Christina M. Tringides, Hamza Ijaz, Anna N. Honko, Makda S. Gebre, Rebecca I. Johnson, Anthony Griffiths, Tal Gilboa, Jingyou Yu, Dan H. Barouch, Chi-An Cheng, Des White, Mark Cartwright, Edward J. Doherty, Nikolaos Dimitrakakis, Amanda R. Graveline, Fernanda Langellotto, Nadia Storm, David R. Walt, Chyenne D. Yeager
Publikováno v:
Advanced Healthcare Materials
The coronavirus disease 2019 (COVID‐19) pandemic demonstrates the importance of generating safe and efficacious vaccines that can be rapidly deployed against emerging pathogens. Subunit vaccines are considered among the safest, but proteins used in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cadaaf0d95bf66a32f4d1a698ddfe9
http://europepmc.org/articles/PMC8652677
http://europepmc.org/articles/PMC8652677
Autor:
Kayla R. Lightbown, Julia B Hicks-Berthet, Michael Super, Anna Waterhouse, Daniel Antonoff, Nikolaos Dimitrakakis, Cheyene N Leslie, Donald E. Ingber, Shanda L. Lightbown, Daniel C. Leslie, Marc B. Ackerman
Publikováno v:
ACS Biomaterials Science & Engineering. 5:420-424
Localized infections caused by biofilm formation on dentures pose a serious health risk for patients, especially the elderly, as they can lead to complications such as pneumonia. Daily enzymatic denture cleaners do not fully prevent biofilm formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed31768f9d8d2f3a3ae1fea1da706d65
https://doi.org/10.1021/acsbiomaterials.8b01214
https://doi.org/10.1021/acsbiomaterials.8b01214
Autor:
Jon M. Dempersmier, Radosław P. Nowak, Eihab Kabha, Pierre P.M. Junghanns, Evangelos Papadopoulos, Eric S. Fischer, Patrick D. Fischer, Ognyan Petrov, Christian Ducho, Nikolaos Dimitrakakis, Christoph Gorgulla, Vladimir Gelev, Haribabu Arthanari, Katherine A. Donovan, Constantine S. Mitsiades, Zi-Fu Wang, Gerhard Wagner, Joann Kalabathula
Publikováno v:
Eur J Med Chem
The eukaryotic translation initiation factor 4E (eIF4E) is the master regulator of cap-dependent protein synthesis. Overexpression of eIF4E is implicated in diseases such as cancer, where dysregulation of oncogenic protein translation is frequently o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7624b60458fe74e310646e63478aba
https://europepmc.org/articles/PMC8846605/
https://europepmc.org/articles/PMC8846605/
Autor:
Anna, Waterhouse, Daniel C, Leslie, Kayla, Lightbown, Daniel, Antonoff, Shanda, Lightbown, Nikolaos, Dimitrakakis, Julia B, Hicks-Berthet, Cheyene N, Leslie, Michael, Super, Donald E, Ingber, Marc B, Ackerman
Publikováno v:
ACS biomaterials scienceengineering. 5(2)
Localized infections caused by biofilm formation on dentures pose a serious health risk for patients, especially the elderly, as they can lead to complications such as pneumonia. Daily enzymatic denture cleaners do not fully prevent biofilm formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a1bbad9b071d8981aeea4058dd592c9
https://pubmed.ncbi.nlm.nih.gov/33405807
https://pubmed.ncbi.nlm.nih.gov/33405807