Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Nikolaos C Kyriakidis"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Hyperactivation of YAP/TAZ, the Hippo pathway downstream effectors, is common in human cancer. The requirement of YAP/TAZ for cancer cell survival in preclinical models, prompted the development of pharmacological inhibitors that suppress th
Externí odkaz:
https://doaj.org/article/81918d5ba10342318d2b7e11ec28ad7f
Autor:
Anthony Loor-Giler, Sara Castillo-Reyes, Silvana Santander-Parra, Manuel Caza, Nikolaos C. Kyriakidis, Antonio J. Piantino Ferreira, Luis Nuñez
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-11 (2024)
Abstract Background Enteric viruses are among the most prominent etiological agents of Runting-Stunting Syndrome (RSS). The Avian Nephritis Virus (ANV) is an astrovirus associated with enteric diseases in poultry, whose early diagnosis is essential f
Externí odkaz:
https://doaj.org/article/e96203206731484c8b4e5e25bb273919
Autor:
María José Ramos-Medina, Gabriela Echeverría-Garcés, Nikolaos C. Kyriakidis, Ángela León Cáceres, Esteban Ortiz-Prado, Jhommara Bautista, Álvaro A. Pérez-Meza, Andrea Abad-Sojos, Karol Nieto-Jaramillo, Samantha Espinoza-Ferrao, Belén Ocaña-Paredes, Andrés López-Cortés
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23682- (2024)
Cardiovascular diseases are the leading cause of death worldwide, with heart failure being a complex condition that affects millions of individuals. Single-nucleus RNA sequencing has recently emerged as a powerful tool for unraveling the molecular me
Externí odkaz:
https://doaj.org/article/e0e718d001024f43bae9c6fd348ce604
Publikováno v:
Viruses, Vol 16, Iss 4, p 574 (2024)
DNA oncoviruses represent an intriguing subject due to their involvement in oncogenesis. These viruses have evolved mechanisms to manipulate the host immune response, facilitating their persistence and actively contributing to carcinogenic processes.
Externí odkaz:
https://doaj.org/article/251cfd21387c4a14b27f5d8c61122294
Autor:
Andrés López-Cortés, Lavanya Prathap, Esteban Ortiz-Prado, Nikolaos C. Kyriakidis, Ángela León Cáceres, Isaac Armendáriz-Castillo, Antonella Vera-Guapi, Verónica Yumiceba, Katherine Simbaña-Rivera, Gabriela Echeverría-Garcés, Jennyfer M. García-Cárdenas, Andy Pérez-Villa, Patricia Guevara-Ramírez, Andrea Abad-Sojos, Jhommara Bautista, Lourdes Puig San Andrés, Nelson Varela, Santiago Guerrero
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access to nutrients due to poor vascularization in the tissue, phenomenon known as hypoxia. Hypoxic tumors are able to regulate the expression of certain gen
Externí odkaz:
https://doaj.org/article/232a46b4edde474ab4010ae0d3483ad3
Autor:
Jorge Luis Vélez Paez, Fernando E. Rueda-Barragán, Sarahí Dueñas-Andrade, Alfonso Rodrigez-Morales, Nikolaos C. Kyriakidis
Publikováno v:
Microbes, Infection and Chemotherapy, Vol 3 (2023)
Sepsis is defined as "an organic dysfunction secondary to the dysregulated response of the patient to an infection." This concept only reveals the tip of the iceberg, the clinical expression of organic failures, without understanding their basis, whi
Externí odkaz:
https://doaj.org/article/7a8fb9c9ec674afa923832260cdaf5f4
Autor:
Esteban Ortiz-Prado, Estefanía Espín, Jorge Vásconez, Nathalia Rodríguez-Burneo, Nikolaos C. Kyriakidis, Andrés López-Cortés
Publikováno v:
Tropical Diseases, Travel Medicine and Vaccines, Vol 7, Iss 1, Pp 1-21 (2021)
Abstract In the Americas, The United States of America, Canada, Mexico, and Brazil are the top vaccine producers and the countries with the leading infrastructure for biological manufacturing. The North American countries have the most demanding legi
Externí odkaz:
https://doaj.org/article/b05a00962c604acd84fbc83352d26e34
Autor:
Nikolaos C. Kyriakidis, Andrés López-Cortés, Eduardo Vásconez González, Alejandra Barreto Grimaldos, Esteban Ortiz Prado
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-17 (2021)
Abstract The new SARS-CoV-2 virus is an RNA virus that belongs to the Coronaviridae family and causes COVID-19 disease. The newly sequenced virus appears to originate in China and rapidly spread throughout the world, becoming a pandemic that, until J
Externí odkaz:
https://doaj.org/article/9fc292bcd3b4444790fed93887bc094b
Autor:
Andrés López-Cortés, Santiago Guerrero, Esteban Ortiz-Prado, Verónica Yumiceba, Antonella Vera-Guapi, Ángela León Cáceres, Katherine Simbaña-Rivera, Ana María Gómez-Jaramillo, Gabriela Echeverría-Garcés, Jennyfer M. García-Cárdenas, Patricia Guevara-Ramírez, Alejandro Cabrera-Andrade, Lourdes Puig San Andrés, Doménica Cevallos-Robalino, Jhommara Bautista, Isaac Armendáriz-Castillo, Andy Pérez-Villa, Andrea Abad-Sojos, María José Ramos-Medina, Ariana León-Sosa, Estefanía Abarca, Álvaro A. Pérez-Meza, Karol Nieto-Jaramillo, Andrea V. Jácome, Andrea Morillo, Fernanda Arias-Erazo, Luis Fuenmayor-González, Luis Abel Quiñones, Nikolaos C. Kyriakidis
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: It is imperative to identify drugs that allow treating symptoms of severe COVID-19. Respiratory failure is the main cause of death in severe COVID-19 patients, and the host inflammatory response at the lungs remains poorly understood.Meth
Externí odkaz:
https://doaj.org/article/e8b07b23be824df88651bfffed4353ac
Autor:
Ismar A. Rivera-Olivero, Aquiles R. Henríquez-Trujillo, Nikolaos C. Kyriakidis, Esteban Ortiz-Prado, Juan Carlos Laglaguano, Alexander Paolo Vallejo-Janeta, Tannya Lozada, Miguel Angel Garcia-Bereguiain, UDLA COVID-19 team
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
BackgroundAlthough RT-qPCR remains the gold-standard for COVID-19 diagnosis, anti-SARS-CoV-2 serology-based assays have been widely used during 2020 as an alternative for individual and mass testing, and are currently used for seroprevalence studies.
Externí odkaz:
https://doaj.org/article/53c35ad4af5346b397d85ca99a2010fe