Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Autor: Thomas W Winkler, Anne E Justice, Mariaelisa Graff, Llilda Barata, Mary F Feitosa, Su Chu, Jacek Czajkowski, Tõnu Esko, Tove Fall, Tuomas O Kilpeläinen, Yingchang Lu, Reedik Mägi, Evelin Mihailov, Tune H Pers, Sina Rüeger, Alexander Teumer, Georg B Ehret, Teresa Ferreira, Nancy L Heard-Costa, Juha Karjalainen, Vasiliki Lagou, Anubha Mahajan, Michael D Neinast, Inga Prokopenko, Jeannette Simino, Tanya M Teslovich, Rick Jansen, Harm-Jan Westra, Charles C White, Devin Absher, Tarunveer S Ahluwalia, Shafqat Ahmad, Eva Albrecht, Alexessander Couto Alves, Jennifer L Bragg-Gresham, Anton J M de Craen, Joshua C Bis, Amélie Bonnefond, Gabrielle Boucher, Gemma Cadby, Yu-Ching Cheng, Charleston W K Chiang, Graciela Delgado, Ayse Demirkan, Nicole Dueker, Niina Eklund, Gudny Eiriksdottir, Joel Eriksson, Bjarke Feenstra, Krista Fischer, Francesca Frau, Tessel E Galesloot, Frank Geller, Anuj Goel, Mathias Gorski, Tanja B Grammer, Stefan Gustafsson, Saskia Haitjema, Jouke-Jan Hottenga, Jennifer E Huffman, Anne U Jackson, Kevin B Jacobs, Åsa Johansson, Marika Kaakinen, Marcus E Kleber, Jari Lahti, Irene Mateo Leach, Benjamin Lehne, Youfang Liu, Ken Sin Lo, Mattias Lorentzon, Jian'an Luan, Pamela A F Madden, Massimo Mangino, Barbara McKnight, Carolina Medina-Gomez, Keri L Monda, May E Montasser, Gabriele Müller, Martina Müller-Nurasyid, Ilja M Nolte, Kalliope Panoutsopoulou, Laura Pascoe, Lavinia Paternoster, Nigel W Rayner, Frida Renström, Federica Rizzi, Lynda M Rose, Kathy A Ryan, Perttu Salo, Serena Sanna, Hubert Scharnagl, Jianxin Shi, Albert Vernon Smith, Lorraine Southam, Alena Stančáková, Valgerdur Steinthorsdottir, Rona J Strawbridge, Yun Ju Sung, Ioanna Tachmazidou, Toshiko Tanaka, Gudmar Thorleifsson, Stella Trompet, Natalia Pervjakova, Jonathan P Tyrer, Liesbeth Vandenput, Sander W van der Laan, Nathalie van der Velde, Jessica van Setten, Jana V van Vliet-Ostaptchouk, Niek Verweij, Efthymia Vlachopoulou, Lindsay L Waite, Sophie R Wang, Zhaoming Wang, Sarah H Wild, Christina Willenborg, James F Wilson, Andrew Wong, Jian Yang, Loïc Yengo, Laura M Yerges-Armstrong, Lei Yu, Weihua Zhang, Jing Hua Zhao, Ehm A Andersson, Stephan J L Bakker, Damiano Baldassarre, Karina Banasik, Matteo Barcella, Cristina Barlassina, Claire Bellis, Paola Benaglio, John Blangero, Matthias Blüher, Fabrice Bonnet, Lori L Bonnycastle, Heather A Boyd, Marcel Bruinenberg, Aron S Buchman, Harry Campbell, Yii-Der Ida Chen, Peter S Chines, Simone Claudi-Boehm, John Cole, Francis S Collins, Eco J C de Geus, Lisette C P G M de Groot, Maria Dimitriou, Jubao Duan, Stefan Enroth, Elodie Eury, Aliki-Eleni Farmaki, Nita G Forouhi, Nele Friedrich, Pablo V Gejman, Bruna Gigante, Nicola Glorioso, Alan S Go, Omri Gottesman, Jürgen Gräßler, Harald Grallert, Niels Grarup, Yu-Mei Gu, Linda Broer, Annelies C Ham, Torben Hansen, Tamara B Harris, Catharina A Hartman, Maija Hassinen, Nicholas Hastie, Andrew T Hattersley, Andrew C Heath, Anjali K Henders, Dena Hernandez, Hans Hillege, Oddgeir Holmen, Kees G Hovingh, Jennie Hui, Lise L Husemoen, Nina Hutri-Kähönen, Pirro G Hysi, Thomas Illig, Philip L De Jager, Shapour Jalilzadeh, Torben Jørgensen, J Wouter Jukema, Markus Juonala, Stavroula Kanoni, Maria Karaleftheri, Kay Tee Khaw, Leena Kinnunen, Steven J Kittner, Wolfgang Koenig, Ivana Kolcic, Peter Kovacs, Nikolaj T Krarup, Wolfgang Kratzer, Janine Krüger, Diana Kuh, Meena Kumari, Theodosios Kyriakou, Claudia Langenberg, Lars Lannfelt, Chiara Lanzani, Vaneet Lotay, Lenore J Launer, Karin Leander, Jaana Lindström, Allan Linneberg, Yan-Ping Liu, Stéphane Lobbens, Robert Luben, Valeriya Lyssenko, Satu Männistö, Patrik K Magnusson, Wendy L McArdle, Cristina Menni, Sigrun Merger, Lili Milani, Grant W Montgomery, Andrew P Morris, Narisu Narisu, Mari Nelis, Ken K Ong, Aarno Palotie, Louis Pérusse, Irene Pichler, Maria G Pilia, Anneli Pouta, Myriam Rheinberger, Rasmus Ribel-Madsen, Marcus Richards, Kenneth M Rice, Treva K Rice, Carlo Rivolta, Veikko Salomaa, Alan R Sanders, Mark A Sarzynski, Salome Scholtens, Robert A Scott, William R Scott, Sylvain Sebert, Sebanti Sengupta, Bengt Sennblad, Thomas Seufferlein, Angela Silveira, P Eline Slagboom, Jan H Smit, Thomas H Sparsø, Kathleen Stirrups, Ronald P Stolk, Heather M Stringham, Morris A Swertz, Amy J Swift, Ann-Christine Syvänen, Sian-Tsung Tan, Barbara Thorand, Anke Tönjes, Angelo Tremblay, Emmanouil Tsafantakis, Peter J van der Most, Uwe Völker, Marie-Claude Vohl, Judith M Vonk, Melanie Waldenberger, Ryan W Walker, Roman Wennauer, Elisabeth Widén, Gonneke Willemsen, Tom Wilsgaard, Alan F Wright, M Carola Zillikens, Suzanne C van Dijk, Natasja M van Schoor, Folkert W Asselbergs, Paul I W de Bakker, Jacques S Beckmann, John Beilby, David A Bennett, Richard N Bergman, Sven Bergmann, Carsten A Böger, Bernhard O Boehm, Eric Boerwinkle, Dorret I Boomsma, Stefan R Bornstein, Erwin P Bottinger, Claude Bouchard, John C Chambers, Stephen J Chanock, Daniel I Chasman, Francesco Cucca, Daniele Cusi, George Dedoussis, Jeanette Erdmann, Johan G Eriksson, Denis A Evans, Ulf de Faire, Martin Farrall, Luigi Ferrucci, Ian Ford, Lude Franke, Paul W Franks, Philippe Froguel, Ron T Gansevoort, Christian Gieger, Henrik Grönberg, Vilmundur Gudnason, Ulf Gyllensten, Per Hall, Anders Hamsten, Pim van der Harst, Caroline Hayward, Markku Heliövaara, Christian Hengstenberg, Andrew A Hicks, Aroon Hingorani, Albert Hofman, Frank Hu, Heikki V Huikuri, Kristian Hveem, Alan L James, Joanne M Jordan, Antti Jula, Mika Kähönen, Eero Kajantie, Sekar Kathiresan, Lambertus A L M Kiemeney, Mika Kivimaki, Paul B Knekt, Heikki A Koistinen, Jaspal S Kooner, Seppo Koskinen, Johanna Kuusisto, Winfried Maerz, Nicholas G Martin, Markku Laakso, Timo A Lakka, Terho Lehtimäki, Guillaume Lettre, Douglas F Levinson, Lars Lind, Marja-Liisa Lokki, Pekka Mäntyselkä, Mads Melbye, Andres Metspalu, Braxton D Mitchell, Frans L Moll, Jeffrey C Murray, Arthur W Musk, Markku S Nieminen, Inger Njølstad, Claes Ohlsson, Albertine J Oldehinkel, Ben A Oostra, Lyle J Palmer, James S Pankow, Gerard Pasterkamp, Nancy L Pedersen, Oluf Pedersen, Brenda W Penninx, Markus Perola, Annette Peters, Ozren Polašek, Peter P Pramstaller, Bruce M Psaty, Lu Qi, Thomas Quertermous, Olli T Raitakari, Tuomo Rankinen, Rainer Rauramaa, Paul M Ridker, John D Rioux, Fernando Rivadeneira, Jerome I Rotter, Igor Rudan, Hester M den Ruijter, Juha Saltevo, Naveed Sattar, Heribert Schunkert, Peter E H Schwarz, Alan R Shuldiner, Juha Sinisalo, Harold Snieder, Thorkild I A Sørensen, Tim D Spector, Jan A Staessen, Bandinelli Stefania, Unnur Thorsteinsdottir, Michael Stumvoll, Jean-Claude Tardif, Elena Tremoli, Jaakko Tuomilehto, André G Uitterlinden, Matti Uusitupa, André L M Verbeek, Sita H Vermeulen, Jorma S Viikari, Veronique Vitart, Henry Völzke, Peter Vollenweider, Gérard Waeber, Mark Walker, Henri Wallaschofski, Nicholas J Wareham, Hugh Watkins, Eleftheria Zeggini, arcOGEN Consortium, CHARGE Consortium, DIAGRAM Consortium, GLGC Consortium, Global-BPGen Consortium, ICBP Consortium, MAGIC Consortium, Aravinda Chakravarti, Deborah J Clegg, L Adrienne Cupples, Penny Gordon-Larsen, Cashell E Jaquish, D C Rao, Goncalo R Abecasis, Themistocles L Assimes, Inês Barroso, Sonja I Berndt, Michael Boehnke, Panos Deloukas, Caroline S Fox, Leif C Groop, David J Hunter, Erik Ingelsson, Robert C Kaplan, Mark I McCarthy, Karen L Mohlke, Jeffrey R O'Connell, David Schlessinger, David P Strachan, Kari Stefansson, Cornelia M van Duijn, Joel N Hirschhorn, Cecilia M Lindgren, Iris M Heid, Kari E North, Ingrid B Borecki, Zoltán Kutalik, Ruth J F Loos

Publikováno v: PLoS Genetics, Vol 12, Iss 6, p e1006166 (2016)

[This corrects the article DOI: 10.1371/journal.pgen.1005378.].

Externí odkaz: https://doaj.org/article/4cc95013f85a4fc193c939c0924ea7db

Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease.

Autor: Karina Banasik, Johanne M Justesen, Malene Hornbak, Nikolaj T Krarup, Anette P Gjesing, Camilla H Sandholt, Thomas S Jensen, Niels Grarup, Asa Andersson, Torben Jørgensen, Daniel R Witte, Annelli Sandbæk, Torsten Lauritzen, Bernard Thorens, Søren Brunak, Thorkild I A Sørensen, Oluf Pedersen, Torben Hansen

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e16542 (2011)

Candidate genes for non-alcoholic fatty liver disease (NAFLD) identified by a bioinformatics approach were examined for variant associations to quantitative traits of NAFLD-related phenotypes.By integrating public database text mining, trans-organism

Externí odkaz: https://doaj.org/article/0cbd53982403493c882e8efdca4fdc26

A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals

Autor: Ehm A. Andersson, Oluf Pedersen, Torben Hansen, Torben Jørgensen, Anders Borglykke, Johanne Marie Justesen, Niels Grarup, Camilla H. Sandholt, Kristine H. Allin, Nikolaj T. Krarup

Publikováno v: Krarup, N T, Borglykke, A, Allin, K H, Sandholt, C H, Justesen, J M, Andersson, E A, Grarup, N, Jørgensen, T, Pedersen, O & Hansen, T 2015, ' A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals ', Atherosclerosis, vol. 240, no. 2, pp. 305-310 . https://doi.org/10.1016/j.atherosclerosis.2015.03.022

BACKGROUND: In Europeans, 45 genetic risk variants for coronary artery disease (CAD) have been identified in genome-wide association studies. We constructed a genetic risk score (GRS) of these variants to estimate the effect on incidence and clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cd024d9a2959ec8aca52c8c6d5d315
https://doi.org/10.1016/j.atherosclerosis.2015.03.022

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

Autor: Daniel F. Gudbjartsson, Gisli Masson, Riyaz S. Patel, Nilesh J. Samani, Alistair S. Hall, Torben Hansen, Andre M. van Rij, Christopher P. Nelson, Svati H. Shah, William E. Kraus, Isleifur Olafsson, Audur Magnusdottir, Mogens Fenger, Gregory T. Jones, Arna B Agustsdottir, Paul Nioi, Gudmundur I. Eyjolfsson, Asgeir Sigurdsson, Ulrik Abildgaard, Thorunn Rafnar, Peter Riis Hansen, Daniel J. Rader, Hannes Helgason, Gudmundur L. Norddahl, Dorine W. Swinkels, Patrick Sulem, Tessel E. Galesloot, Torsten Lauritzen, Unnur Thorsteinsdottir, Kari Stefansson, Henrik Vestergaard, Hilma Holm, Muredach P. Reilly, Anna Helgadottir, Lambertus A. Kiemeney, Olof Sigurdardottir, Allan Linneberg, Nele Friedrich, Arshed A. Quyyumi, Peter S. Braund, Allan I Levey, Aslaug Jonasdottir, Michael J.A. Williams, Niels Grarup, Gudmundur Thorgeirsson, Valgerdur Steinthorsdottir, Torben Jørgensen, Nikolaj T. Krarup, Oluf Pedersen, Gudmar Thorleifsson, Salim S. Hayek, Solveig Gretarsdottir, Ingileif Jonsdottir, Anders Galløe

Publikováno v: The New England Journal of Medicine, 374, 22, pp. 2131-41
The New England Journal of Medicine, 374, 2131-41
Nioi, P, Sigurdsson, A, Thorleifsson, G, Helgason, H, Agustsdottir, A B, Norddahl, G L, Helgadottir, A, Magnusdottir, A, Jonasdottir, A, Grétarsdóttir, S, Jonsdottir, I, Steinthorsdottir, V, Rafnar, T, Swinkels, D W, Galesloot, T E, Grarup, N, Jørgensen, T, Vestergaard, H, Hansen, T, Lauritzen, T, Linneberg, A, Friedrich, N, Krarup, N T, Fenger, M, Abildgaard, U, Hansen, P R, Galløe, A M, Braund, P S, Nelson, C P, Hall, A S, Williams, M J A, van Rij, A M, Jones, G T, Patel, S R, Levey, A I, Hayek, S, Shah, S H, Reilly, M, Eyjolfsson, G I, Sigurdardottir, O, Olafsson, I, Kiemeney, L A, Quyyumi, A A, Rader, D J, Kraus, W E, Samani, N J, Pedersen, O, Thorgeirsson, G, Masson, G, Holm, H, Gudbjartsson, D F, Sulem, P, Thorsteinsdottir, U & Stefansson, K 2016, ' Variant ASGR1 associated with a reduced risk of coronary artery disease ', The New England Journal of Medicine, vol. 374, no. 22, pp. 2131-2141 . https://doi.org/10.1056/NEJMoa1508419
Nioi, P, Sigurdsson, A S, Thorleifsson, G, Helgason, H, Agustsdottir, A B, Norddahl, G L, Helgadottir, A, Magnúsdóttir, A, Jonasdottir, A, Grétarsdóttir, S, Jónsdóttir, I S, Steinthorsdottir, V, Rafnar, T, Swinkels, D W, Galesloot, T E, Grarup, N, Jorgensen, T, Vestergaard, H, Hansen, T, Lauritzen, T, Linneberg, A, Friedrich, N, Krarup, N T, Fenger, M, Abildgaard, U, Hansen, P R, Galloe, A M, Braund, P S, Nelson, C P, Hall, A S, Williams, M J A, van Rij, A M, Jones, G T, Patel, S R, Levey, A I, Hayek, S, Shah, S H, Reilly, M M, Eyjolfsson, G I, Sigurdardottir, O, Olafsson, I, Kiemeney, L A, Quyyumi, A A, Rader, D J, Kraus, W E, Samani, N J, Pedersen, O, Thorgeirsson, G, Masson, G, Holm, H, Gudbjartsson, D F, Sulem, P, Thorsteinsdottir, U & Stefansson, K 2016, ' Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease ', The New England Journal of Medicine, vol. 374, no. 22, pp. 2131-2141 . https://doi.org/10.1056/NEJMoa1508419
Nioi, P, Sigurdsson, A, Thorleifsson, G, Helgason, H, Agustsdottir, A B, Norddahl, G L, Helgadottir, A, Magnusdottir, A, Jonasdottir, A, Gretarsdottir, S, Jonsdottir, I, Steinthorsdottir, V, Rafnar, T, Swinkels, D W, Galesloot, T E, Grarup, N, Jørgensen, T, Vestergaard, H, Hansen, T, Lauritzen, T, Linneberg, A, Friedrich, N, Krarup, N T, Fenger, M, Abildgaard, U, Hansen, P R, Galløe, A M, Braund, P S, Nelson, C P, Hall, A S, Williams, M J A, van Rij, A M, Jones, G T, Patel, R S, Levey, A I, Hayek, S, Shah, S H, Reilly, M, Eyjolfsson, G I, Sigurdardottir, O, Olafsson, I, Kiemeney, L A, Quyyumi, A A, Rader, D J, Kraus, W E, Samani, N J, Pedersen, O, Thorgeirsson, G, Masson, G, Holm, H, Gudbjartsson, D, Sulem, P, Thorsteinsdottir, U & Stefansson, K 2016, ' Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease ', The New England Journal of Medicine, vol. 374, no. 22, pp. 2131-2141 . https://doi.org/10.1056/NEJMoa1508419

BACKGROUNDSeveral sequence variants are known to have effects on serum levels of non-high-density lipoprotein (HDL) cholesterol that alter the risk of coronary artery disease.METHODSWe sequenced the genomes of 2636 Icelanders and found variants that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8477856a4eaec7734e261bdbd7c19eed
https://hdl.handle.net/2066/171918

Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population

Autor: Johanne Marie Justesen, Torben Hansen, Niels Grarup, Nikolaj T. Krarup, Kristine H. Allin, Anders Borglykke, Camilla H. Sandholt, Torben Jørgensen, Oluf Pedersen, Allan Linneberg

Publikováno v: Justesen, J M, Allin, K H, Sandholt, C H, Borglykke, A, Krarup, N T, Grarup, N, Linneberg, A, Jørgensen, T, Hansen, T & Pedersen, O 2015, ' Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population ', Circulation. Cardiovascular Genetics (Online), vol. 8, no. 3, pp. 465-472 . https://doi.org/10.1161/CIRCGENETICS.114.000637

Background— There are several well-established lifestyle factors influencing dyslipidemia and currently; 157 genetic susceptibility loci have been reported to be associated with serum lipid levels at genome-wide statistical significance. However, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f2d3ad264160e9587a56b3b47bca5c
https://vbn.aau.dk/da/publications/32da0f58-cc6a-4141-b3a1-cf08038632b5