Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Nikolai V. Tomilin"'
Autor:
Alexey S. Gladchuk, Elena S. Silyavka, Vladimir V. Shilovskikh, Vladimir N. Bocharov, Ivan M. Zorin, Nikolai V. Tomilin, Nikita A. Stepashkin, Marina L. Alexandrova, Nikolai V. Krasnov, Alexander Yu. Gorbunov, Vladimir N. Babakov, Nikolai G. Sukhodolov, Artem A. Selyutin, Ekaterina P. Podolskaya
Publikováno v:
Thin Solid Films. 756:139374
Publikováno v:
Cell and Tissue Biology. 5:531-535
DNA double-strand breaks (DSBs) which occurs in cells after ionizing radiation (IR) or chemical agents are the most dangerous lesions in eukariotic cells, which leads to cell death or chromosome abberations and cancer. One of the earliest response of
Publikováno v:
Biochimie. 93:306-313
Peroxiredoxins (PRDXs) represent a conserved family of six antioxidant proteins which are widely expressed in different organisms. Human PRDX5 is detected in the cytosol and nucleus and can also target peroxisomes and mitochondria. However, it remain
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 685:54-60
Covalent modifications of histones in chromatin play an important role in regulation of eukaryotic gene expression and DNA repair. Formation of double-strand breaks (DSBs) in DNA is followed by the rapid local phosphorylation of the C-terminal serine
Autor:
Nikolai V. Tomilin, Vladimir B. Serikov, L. V. Solovjeva, Nadezhda Pleskach, Denis Firsanov, Maria Svetlova
Publikováno v:
Radiation Research. 171:419-424
Forskolin is a natural compound found in the coleus herb that activates the enzyme adenylate cyclase and increases the concentration of intracellular cyclic AMP (cAMP). This chemical is widely used as a stimulating food additive. It is unknown whethe
Publikováno v:
Cell and Tissue Biology. 2:457-462
Promoter fragments of deoxyribonuclease II (DNAse II) and calcium-modulating cyclophilin ligand (CAML) associated with Alu family repeats have been inserted into luciferase reporter vectors. The constructs were introduced into A549 and HEK293 cell li
Publikováno v:
Cell and Tissue Biology. 2:217-221
Using computer-based methods, we determined the global distribution of short interspersed nuclear elements (SINEs) on human and mouse X chromosomes. It was shown that this distribution was similar to the distribution of CpG islands and genes, but was
Autor:
Nikolai V. Tomilin
Publikováno v:
BioEssays. 30:338-348
Genomes of higher eukaryotes contain abundant non-coding repeated sequences whose overall biological impact is unclear. They comprise two categories. The first consists of retrotransposon-derived elements. These are three major families of retroeleme
Publikováno v:
FEBS Journal. 274:5804-5814
Peroxiredoxin V (PRDX5) is a member of the family of mammalian proteins that neutralize reactive oxygen species. The PRDX5 gene is constitutively expressed at a high level in many human tissues, but functional elements of its promoter responsible for
Publikováno v:
Chromosome Research. 15:787-797
Double-strand DNA breaks (DSBs) induced by ionizing radiation can be visualized in human cells using antibodies against Ser-139 phosphorylated histone H2AX (gamma-H2AX). Large gamma-H2AX foci are seen in the nucleus fixed 1 hour after irradiation and