Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nikolai Slynko"'
Autor:
Nikolai Slynko, Lyudmila F. Gulyaeva, Elena N. Pivovarova, Vladimir O. Pustylnyak, Vyacheslav V. Lyakhovich
Publikováno v:
Life Sciences. 85:815-821
Aim The aim of the current study was to investigate the species-specific induction of CYP2B by 2,4,6-tryphenyldioxane-1,3 (TPD) in relation to activation of CAR. Main methods 7-Pentoxyresorufin O-dealkylase (PROD) activity, RT-PCR, Western blot, Elec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d42c036e6ee94446fe3cadd292d28dd
https://doi.org/10.1016/j.lfs.2009.10.015
https://doi.org/10.1016/j.lfs.2009.10.015
Autor:
Nikolai Slynko, Yuliya Kazakova, Vladimir O. Pustylnyak, Lyudmila F. Gulyaeva, Andrei A. Yarushkin
Publikováno v:
Chemico-biological interactions. 194(2-3)
2,4,6-Triphenyldioxane-1,3 (TPD) is a highly effective inducer of CYP2В in rats, but not in mice. Several analogs of TPD were synthesized. All substituents were entered into the same position of TPD (R = H, cisTPD and transTPD; R = N(CH3)2, transpDM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6996efa1ff265c4164fd37ed2900eee
https://pubmed.ncbi.nlm.nih.gov/21982821
https://pubmed.ncbi.nlm.nih.gov/21982821
Autor:
Ekaterina Kachaylo, Nikolai Slynko, Andrei A. Yarushkin, Vladimir O. Pustylnyak, Lyudmila F. Gulyaeva, Vyacheslav V. Lyakhovich
Publikováno v:
Chemico-biological interactions. 192(3)
2,4,6-Triphenyldioxane-1,3 (TPD) is a highly effective species-specific inducer of CYP2В in rats. Several analogs of TPD were synthesized to verify a hypothesis that minor changes in the inducer structure can cause changes in induction abilities (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5be0ccc6f5c4e0cb1eca4544c319818
https://pubmed.ncbi.nlm.nih.gov/21453690
https://pubmed.ncbi.nlm.nih.gov/21453690
Autor:
Nikolai Slynko, Lyudmila F. Gulyaeva, L. Yu. Zacharova, Vladimir O. Pustylnyak, Vyacheslav V. Lyakhovich
Publikováno v:
Biochemistry. Biokhimiia. 69(10)
CYP2B gene expression in liver of rats treated with phenobarbital and triphenyldioxane at early stage of induction (40 min-18 h) was studied using electrophoretic mobility shift assay (EMSA) and RT-PCR. During first 6 h after induction, differences i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a312063996444061bd135e34c63b98
https://pubmed.ncbi.nlm.nih.gov/15527410
https://pubmed.ncbi.nlm.nih.gov/15527410