Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Nikolai O, Artemyev"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Ric8A regulates G protein α-subunits (Gα) by acting as a guanine nucleotide exchange factor (GEF) and a Gα chaperone. Here, the authors solve the crystal structures of free and Gα fragment bound Ric8A, and provide insights into the structural bas
Externí odkaz:
https://doaj.org/article/bea98bc56e5b4376a6be5042e63b46f6
Autor:
Dhiraj Srivastava, Ravi P. Yadav, Shivangi M. Inamdar, Zhen Huang, Maxim Sokolov, Kimberly Boyd, Nikolai O. Artemyev
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Transducin mediates signal transduction in a classical G protein-coupled receptor (GPCR) phototransduction cascade. Interactions of transducin with the receptor and the effector molecules had been extensively investigated and are currently defined at
Externí odkaz:
https://doaj.org/article/87277b3e108444508fb5a654a73265f5
Autor:
Ala Morshedian, Gabriela Sendek, Sze Yin Ng, Kimberly Boyd, Roxana A. Radu, Mingyao Liu, Nikolai O. Artemyev, Alapakkam P. Sampath, Gordon L. Fain
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 11
J Neurosci
J Neurosci
The high sensitivity of night vision requires that rod photoreceptors reliably and reproducibly signal the absorption of single photons, a process that depends on tight regulation of intracellular cGMP concentration through the phototransduction casc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aee363012006ca0a1a9894e1d711434
https://doi.org/10.1523/jneurosci.2119-21.2021
https://doi.org/10.1523/jneurosci.2119-21.2021
Autor:
Christie K. Campla, Ulisse Bocchero, Ryan Strickland, Jacob Nellissery, Jayshree Advani, Irina Ignatova, Dhiraj Srivastava, Angel M. Aponte, Yuchen Wang, Jessica Gumerson, Kirill Martemyanov, Nikolai O. Artemyev, Johan Pahlberg, Anand Swaroop
Publikováno v:
eNeuro. 9(5)
Trafficking of transducin (Gαt) in rod photoreceptors is critical for adaptive and modulatory responses of the retina to varying light intensities. In addition to fine-tuning phototransduction gain in rod outer segments (OSs), light-induced transloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6847c0098623f0c470d2e7abc86c4ed0
https://pubmed.ncbi.nlm.nih.gov/36180221
https://pubmed.ncbi.nlm.nih.gov/36180221
Autor:
Katherine E. Fehlhaber, Anurima Majumder, Kimberly K. Boyd, Khris G. Griffis, Nikolai O. Artemyev, Gordon L. Fain, Alapakkam P. Sampath
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8106
Mammalian UNC119 is a ciliary trafficking chaperone highly expressed in the inner segment of retinal photoreceptors. Previous research has shown that UNC119 can bind to transducin, the synaptic ribbon protein RIBEYE, and the calcium-binding protein C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bcb0b61c74006f754f2475ba3fd80b
https://doi.org/10.3390/ijms24098106
https://doi.org/10.3390/ijms24098106
Autor:
Terry C. Yin, Jonathan G. Van Vranken, Dhiraj Srivastava, Jissele A. Verdinez, Aschleigh E. Graham, Susan A. Walsh, Michael A. Acevedo, Robert J. Kerns, Nikolai O. Artemyev, Steven P. Gygi, Julien Albert Sebag
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca80afd0f7b10eeb06fe17af721ce13c
https://doi.org/10.2139/ssrn.4251792
https://doi.org/10.2139/ssrn.4251792
Publikováno v:
Structure. 31:309-317.e5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c12a9d38fbda00e2ec111c1f622bb9bf
https://doi.org/10.1016/j.str.2022.12.014
https://doi.org/10.1016/j.str.2022.12.014
Autor:
Glenn Yiu, Yumei Li, Nikolai O. Artemyev, Kota N. Gopalakrishna, Jun Wang, Jeffrey Rogers, Kimberly K. Boyd, R. Alan Harris, Laura Garzel, Ori Pomerantz, Rui Chen, Yijun Huang, Sara M Thomasy, J. Timothy Stout, Ashley N. Cameron, Muthuswamy Raveendran, Ala Moshiri, Qingnan Liang, Sarah M. Davis, Christopher J. Murphy, Jeffrey A. Roberts, Soohyun Kim
Publikováno v:
Journal of Clinical Investigation. 129:863-874
Inherited retinal degenerations are a common cause of untreatable blindness worldwide, with retinitis pigmentosa and cone dystrophy affecting approximately 1 in 3500 and 1 in 10,000 individuals, respectively. A major limitation to the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9ae5bcc61166d5868cbf2ae6bca5b31
https://doi.org/10.1172/jci123980
https://doi.org/10.1172/jci123980
Autor:
Gaël Manes, Pallavi Cheguru, Anurima Majumder, Béatrice Bocquet, Audrey Sénéchal, Nikolai O Artemyev, Christian P Hamel, Philippe Brabet
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95768 (2014)
Autosomal dominant congenital stationary night blindness (adCSNB) is caused by mutations in three genes of the rod phototransduction cascade, rhodopsin (RHO), transducin α-subunit (GNAT1), and cGMP phosphodiesterase type 6 β-subunit (PDE6B). In mos
Externí odkaz:
https://doaj.org/article/7f003c8183e14ddb951cea4178a6b4b4
Autor:
Sheila A. Baker, Brittany Williams, Paul J Derr, Kate L Randall, Ravi P. Yadav, Amy S. Lee, Luca Della Santina, Jussara Hagen, Vasily Kerov, Nikolai O. Artemyev, J. Wesley Maddox, Mrinalini Hoon
Publikováno v:
eLife, Vol 9 (2020)
Synapses are fundamental information processing units that rely on voltage-gated Ca2+(Cav) channels to trigger Ca2+-dependent neurotransmitter release. Cavchannels also play Ca2+-independent roles in other biological contexts, but whether they do so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37b94a0eef38ef5ad8fc6f58512c533
https://doi.org/10.7554/elife.62184
https://doi.org/10.7554/elife.62184