Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Nikolai N. Sluchanko"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Carotenoids are hydrophobic pigments binding to diverse carotenoproteins, many of which remain unexplored. Focusing on yellow gregarious locusts accumulating cuticular carotenoids, here we use engineered Escherichia coli cells to reconstitut
Externí odkaz:
https://doaj.org/article/69543eae6d5f449b8ac847240b06fa6b
Autor:
Fedor D. Kornilov, Yury B. Slonimskiy, Daria A. Lunegova, Nikita A. Egorkin, Anna G. Savitskaya, Sergey Yu. Kleymenov, Eugene G. Maksimov, Sergey A. Goncharuk, Konstantin S. Mineev, Nikolai N. Sluchanko
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Fasciclins (FAS1) are ancient adhesion protein domains with no common small ligand binding reported. A unique microalgal FAS1-containing astaxanthin (AXT)-binding protein (AstaP) binds a broad repertoire of carotenoids by a largely unknown m
Externí odkaz:
https://doaj.org/article/78b6c2636a5a4b1aa2163e97ab3973a8
Autor:
Marcus Moldenhauer, Hsueh-Wei Tseng, Anastasia Kraskov, Neslihan N. Tavraz, Igor A. Yaroshevich, Peter Hildebrandt, Nikolai N. Sluchanko, Georg A. Hochberg, Lars-Oliver Essen, Nediljko Budisa, Lukas Korf, Eugene G. Maksimov, Thomas Friedrich
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Dissecting the intricate networks of covalent and non-covalent interactions that stabilize complex protein structures is notoriously difficult and requires subtle atomic-level exchanges to precisely affect local chemical functionality.
Externí odkaz:
https://doaj.org/article/6ed6139269b24933818f17479db45d3c
Autor:
Georgy V. Tsoraev, Elena A. Protasova, Elizaveta A. Klimanova, Yury L. Ryzhykau, Alexander I. Kuklin, Yury S. Semenov, Baosheng Ge, Wenjun Li, Song Qin, Thomas Friedrich, Nikolai N. Sluchanko, Eugene G. Maksimov
Publikováno v:
Structural Dynamics, Vol 9, Iss 5, Pp 054701-054701-11 (2022)
The structural organization of natural pigment-protein complexes provides a specific environment for the chromophore groups. Yet, proteins are inherently dynamic and conformationally mobile. In this work, we demonstrate the heterogeneity of chromopho
Externí odkaz:
https://doaj.org/article/c6fb86fbc9064e07bac4c672910d7588
Autor:
Igor A. Yaroshevich, Eugene G. Maksimov, Nikolai N. Sluchanko, Dmitry V. Zlenko, Alexey V. Stepanov, Ekaterina A. Slutskaya, Yury B. Slonimskiy, Viacheslav S. Botnarevskii, Alina Remeeva, Ivan Gushchin, Kirill Kovalev, Valentin I. Gordeliy, Ivan V. Shelaev, Fedor E. Gostev, Dmitry Khakhulin, Vladimir V. Poddubnyy, Timofey S. Gostev, Dmitry A. Cherepanov, Tomáš Polívka, Miroslav Kloz, Thomas Friedrich, Vladimir Z. Paschenko, Victor A. Nadtochenko, Andrew B. Rubin, Mikhail P. Kirpichnikov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Yaroshevich et al. present a chemical reaction mechanism of a 35-kDa blue light-triggered photoreceptor, the Orange Carotenoid Protein (OCP). They find that photoactivation critically involves the transient formation of a protonated ketocarotenoid (o
Externí odkaz:
https://doaj.org/article/40cdd7274af644f0968f4c7f7500f01e
Autor:
Gergo Gogl, Kristina V. Tugaeva, Pascal Eberling, Camille Kostmann, Gilles Trave, Nikolai N. Sluchanko
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
14-3-3 proteins recognize phosphorylated motifs within numerous protein partners. Here, the authors characterize the binding of all human 14-3-3 isoforms to four E6 oncoproteins, and identify a fixed order of 14-3-3 binding affinities that is conserv
Externí odkaz:
https://doaj.org/article/1012e611587b4449b559fa63901828a2
Autor:
Alexey N. Semenov, Eugene G. Maksimov, Anastasia M. Moysenovich, Marina A. Yakovleva, Georgy V. Tsoraev, Alla A. Ramonova, Evgeny A. Shirshin, Nikolai N. Sluchanko, Tatiana B. Feldman, Andrew B. Rubin, Mikhail P. Kirpichnikov, Mikhail A. Ostrovsky
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 413 (2023)
Lipofuscin of retinal pigment epithelium (RPE) cells is a complex heterogeneous system of chromophores which accumulates as granules during the cell’s lifespan. Lipofuscin serves as a source of various cytotoxic effects linked with oxidative stress
Externí odkaz:
https://doaj.org/article/b23b1696131d4d6194be47326a1320f3
Autor:
Vladislav M. Shatov, Lydia K. Muranova, Maria A. Zamotina, Nikolai N. Sluchanko, Nikolai B. Gusev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1085 (2023)
The α-crystallin domain (ACD) is the hallmark of a diverse family of small heat shock proteins (sHsps). We investigated some of the ACD properties of five human sHsps as well as their interactions with different full-length sHsps. According to size-
Externí odkaz:
https://doaj.org/article/1a34995996894784a6fa26697cef6fca
Autor:
Alexey N. Semenov, Danil A. Gvozdev, Dmitry V. Zlenko, Elena A. Protasova, Anastasia R. Khashimova, Evgenia Yu. Parshina, Adil A. Baizhumanov, Natalia Yu. Lotosh, Eleonora E. Kim, Yuriy N. Kononevich, Alexey A. Pakhomov, Alla A. Selishcheva, Nikolai N. Sluchanko, Evgeny A. Shirshin, Eugene G. Maksimov
Publikováno v:
Membranes, Vol 12, Iss 10, p 905 (2022)
Carotenoids are potent antioxidants with a wide range of biomedical applications. However, their delivery into human cells is challenging and relatively inefficient. While the use of natural water-soluble carotenoproteins capable to reversibly bind c
Externí odkaz:
https://doaj.org/article/93579752460a4033bda2f89f178b9264
Autor:
Alexey V. Samokhvalov, Irina V. Safenkova, Sergei A. Eremin, Artem N. Bonchuk, Oksana G. Maksimenko, Nikolai N. Sluchanko, Anatoly V. Zherdev, Boris B. Dzantiev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4876 (2022)
Short oligonucleotides are widely used for the construction of aptamer-based sensors and logical bioelements to modulate aptamer–ligand binding. However, relationships between the parameters (length, location of the complementary region) of oligonu
Externí odkaz:
https://doaj.org/article/14be0c7bbdb442ba88940122a1114a7e