Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Nikolai Klena"'
Autor:
Jana Muroňová, Zine Eddine Kherraf, Elsa Giordani, Emeline Lambert, Simon Eckert, Caroline Cazin, Amir Amiri-Yekta, Magali Court, Geneviève Chevalier, Guillaume Martinez, Yasmine Neirijnck, Francoise Kühne, Lydia Wehrli, Nikolai Klena, Virginie Hamel, Lisa De Macedo, Jessica Escoffier, Paul Guichard, Charles Coutton, Selima Fourati Ben Mustapha, Mahmoud Kharouf, Anne-Pacale Bouin, Raoudha Zouari, Nicolas Thierry-Mieg, Serge Nef, Stefan Geimer, Corinne Loeuillet, Pierre F Ray, Christophe Arnoult
Publikováno v:
eLife, Vol 12 (2024)
From a cohort of 167 infertile patients suffering from multiple morphological abnormalities of the flagellum (MMAF), pathogenic bi-allelic mutations were identified in the CCDC146 gene. In somatic cells, CCDC146 is located at the centrosome and at mu
Externí odkaz:
https://doaj.org/article/078af173188c4adb858332ae057a3a05
Publikováno v:
Bio-Protocol, Vol 13, Iss 17 (2023)
Expansion microscopy is an innovative method that enables super-resolution imaging of biological materials using a simple confocal microscope. The principle of this method relies on the physical isotropic expansion of a biological specimen cross-link
Externí odkaz:
https://doaj.org/article/ac95c30245e140c6a3aad894ac038165
Autor:
Simona Angerani, Eric Lindberg, Nikolai Klena, Christopher K. E. Bleck, Charlotte Aumeier, Nicolas Winssinger
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Monitoring the activity of the processive motor protein kinesin-1 in live cells is currently difficult. Here the authors report the fluorogenic small molecule QPD-OTf, a kinesin-1 substrate that causes activity-dependent dye precipitation.
Externí odkaz:
https://doaj.org/article/84c103ff473b4a30af353c47c941bdf3
Autor:
Jovenal T. San Agustin, Nikolai Klena, Kristi Granath, Ashok Panigrahy, Eileen Stewart, William Devine, Lara Strittmatter, Julie A. Jonassen, Xiaoqin Liu, Cecilia W. Lo, Gregory J. Pazour
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Using forward genetic screen in fetal mice, Gregory Pazour and colleagues describe mutants affecting kidney/urinary tract development. The authors also show that mutants that cause kidney defects overlaps with those leading to congenital heart defect
Externí odkaz:
https://doaj.org/article/24ebdd773ad74cf7bafc2e4b2c563c39
Autor:
Jovenal T. San Agustin, Nikolai Klena, Kristi Granath, Ashok Panigrahy, Eileen Stewart, William Devine, Lara Strittmatter, Julie A. Jonassen, Xiaoqin Liu, Cecilia W. Lo, Gregory J. Pazour
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7 Article number:11103 (2016); Published 22 March 2016; Updated 8 June 2016 In Fig. 6 of this Article, defects in the tectonic complex were inadvertently labelled during the production process as causing postnatal, rather than p
Externí odkaz:
https://doaj.org/article/16b91fd4130143c3929e6aa9da1537f3
Autor:
Jana Muroňová, Zine-Eddine Kherraf, Elsa Giordani, Simon Eckert, Caroline Cazin, Amir Amiri-Yekta, Emeline lambert, Geneviève Chevalier, Guillaume Martinez, Yasmine Neirijnck, Francoise Kühne, Lydia Wehrli, Nikolai Klena, Virginie Hamel, Jessica Escoffier, Paul Guichard, Charles Coutton, Selima Fourati Ben Mustapha, Mahmoud Kharouf, Raoudha Zouari, Nicolas Thierry-Mieg, Serge Nef, Stefan Geimer, Corinne Loeuillet, Pierre Ray, Christophe Arnoult
Genetic mutations are a recurrent cause of male infertility. Multiple morphological abnormalities of the flagellum (MMAF) syndrome is a heterogeneous genetic disease, with which more than 50 genes have been linked. Nevertheless, for 50% of patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63562146c7e0493193e24d7308a88040
https://doi.org/10.1101/2023.02.27.530236
https://doi.org/10.1101/2023.02.27.530236
Publikováno v:
Nature Methods
Cryofixation has proven to be the gold standard for efficient preservation of native cell ultrastructure compared to chemical fixation, but this approach is not widely used in fluorescence microscopy owing to implementation challenges. Here, we devel
Autor:
Hugo van den Hoek, William Wan, Miroslava Schaffer, Wolfgang Baumeister, Gonzalo Alvarez Viar, Nikolai Klena, Benjamin D. Engel, Philipp Erdmann, Paul Guichard, Juergen M. Plitzko, Mareike A Jordan, Virginie Hamel, Gaia Pigino
The cilium is an antenna-like organelle that performs numerous cellular functions, including motility, sensing, and signaling. The base of the cilium contains a selective barrier that regulates the entry of large intraflagellar transport (IFT) trains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b4785fd2ade0684ff6a4fac408acab3
https://doi.org/10.1101/2021.10.17.464685
https://doi.org/10.1101/2021.10.17.464685
Autor:
Nicolas Winssinger, Nikolai Klena, Eric Lindberg, Simona Angerani, Christopher K. E. Bleck, Charlotte Aumeier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol. 12, No 1463 (2021)
Nature Communications
Nature Communications, Vol. 12, No 1463 (2021)
Nature Communications
Kinesin-1 is a processive motor protein that uses ATP-derived energy to transport a variety of intracellular cargoes toward the cell periphery. The ability to visualize and monitor kinesin transport in live cells is critical to study the myriad of fu
Autor:
Eric Lindberg, Nicolas Winssinger, Charlotte Aumeier, Simona Angerani, Nikolai Klena, Christopher K. E. Bleck
Kinesin-1 is a processive motor protein that uses ATP-derived energy to transport a variety of intracellular cargoes toward the cell periphery. As tracks for cargo delivery, kinesin-1 uses a subset of microtubules within the dense microtubule network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4020a2ee64c9b4747ad8158236dbdee