Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nikolai Hecker"'
Autor:
Henrike Indrischek, Juliane Hammer, Anja Machate, Nikolai Hecker, Bogdan Kirilenko, Juliana Roscito, Stefan Hans, Caren Norden, Michael Brand, Michael Hiller
Publikováno v:
eLife, Vol 11 (2022)
Despite decades of research, knowledge about the genes that are important for development and function of the mammalian eye and are involved in human eye disorders remains incomplete. During mammalian evolution, mammals that naturally exhibit poor vi
Externí odkaz:
https://doaj.org/article/401fc606f4a84ae2a09373993f44d03c
Autor:
Mark S. Springer, Christopher A. Emerling, John Gatesy, Jason Randall, Matthew A. Collin, Nikolai Hecker, Michael Hiller, Frédéric Delsuc
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-19 (2019)
Abstract Background The gene for odontogenic ameloblast-associated (ODAM) is a member of the secretory calcium-binding phosphoprotein gene family. ODAM is primarily expressed in dental tissues including the enamel organ and the junctional epithelium,
Externí odkaz:
https://doaj.org/article/e0e85f562cb744a6afdeb5ca214bc1c5
Autor:
Virag Sharma, Nikolai Hecker, Juliana G. Roscito, Leo Foerster, Bjoern E. Langer, Michael Hiller
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Gene losses are generally considered detrimental, or at best neutral. Here, Sharma and colleagues present a new comparative genomics method to detect gene losses and highlight cases of gene losses in mammals that have potentially contributed to adapt
Externí odkaz:
https://doaj.org/article/a37564bac57644bdaaa74f2b2bf0bfd3
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Anatomical subdivisions of the human brain can be associated with different neuronal functions. This functional diversification is reflected by differences in gene expression. By analyzing post-mortem gene expression data from the Allen Brai
Externí odkaz:
https://doaj.org/article/83d500d9e1854594a7000a1f6d217009
Autor:
Virag Sharma, Nikolai Hecker, Juliana G. Roscito, Leo Foerster, Bjoern E. Langer, Michael Hiller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/2d39117bb1314197a77fb5945a94c3a5
Autor:
Nikolai Hecker, Carsten Stephan, Hans-Joachim Mollenkopf, Klaus Jung, Robert Preissner, Hellmuth-A Meyer
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64543 (2013)
BackgroundMicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. It has been proposed that miRNAs play an important role in cancer development and progression. Their ability to affect multiple gene pathways by targeting various m
Externí odkaz:
https://doaj.org/article/7bcbe37186fb490f95b924c9eedef52a
Autor:
Carmen Bravo González-Blas, Seppe De Winter, Gert Hulselmans, Nikolai Hecker, Irina Matetovici, Valerie Christiaens, Suresh Poovathingal, Jasper Wouters, Sara Aibar, Stein Aerts
Joint profiling of chromatin accessibility and gene expression of individual cells provides an opportunity to decipher enhancer-driven gene regulatory networks (eGRN). Here we present a new method for the inference of eGRNs, called SCENIC+. SCENIC+ p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d740f08177a518541d2c32bf3b39a87b
https://doi.org/10.1101/2022.08.19.504505
https://doi.org/10.1101/2022.08.19.504505
Autor:
Henrike Indrischek, Juliane Hammer, Anja Machate, Nikolai Hecker, Bogdan Kirilenko, Juliana Roscito, Stefan Hans, Caren Norden, Michael Brand, Michael Hiller
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7394154670eaf9d9490847e41f6c72e9
https://doi.org/10.7554/elife.77999.sa2
https://doi.org/10.7554/elife.77999.sa2
Autor:
M. Foote, A.-W. Ahmed, Ana Luiza Fonseca Destro, B. K. Lim, Nikolai Hecker, Martin Pippel, M. Bontempo Freitas, A. Morales, T. Brown, Michael Hiller, Tilman Schell, Axel Janke, B. Kirilenko, M. Blumer, J. A. Oliveira, David Jebb, Carola Greve
Publikováno v:
Science Advances. 8
Feeding exclusively on blood, vampire bats represent the only obligate sanguivorous lineage among mammals. To uncover genomic changes associated with adaptations to this unique dietary specialization, we generated a new haplotype-resolved reference-q
Autor:
Juliana Gusson Roscito, Katrin Sameith, Bogdan Mikhailovich Kirilenko, Nikolai Hecker, Sylke Winkler, Andreas Dahl, Miguel Trefaut Rodrigues, Michael Hiller
Publikováno v:
Cell reports. 38(3)
Loss of limbs evolved many times in squamate reptiles. Here we investigated the genomic basis of convergent limb loss in reptiles. We sequenced the genomes of a closely related pair of limbless-limbed gymnophthalmid lizards and performed a comparativ