Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Nikolai Danchev"'
Autor:
Ivanka Kostadinova, Nikolai Danchev, Boycho Landzhov, Dobrina Tsvetkova, Lyubomir Marinov, Ivalina Ivanova
Publikováno v:
Pharmacia, Vol 70, Iss 4, Pp 967-972 (2023)
In the current study, we investigated the effect of creatine monohydrate (CrM) and newly synthesized creatine lysinate (CrLys) in tail suspension (TST) and rotarod tests and their influence on the histology of the skeletal muscles. In the TST, a slig
Externí odkaz:
https://doaj.org/article/992a52dee1f24158afabe0215f48f597
Autor:
Ivanka Kostadinova, Nikolai Danchev, Boycho Landzhov, Lyubomir Marinov, Ivalina Ivanova, Dobrina Tsvetkova
Publikováno v:
Pharmacia, Vol 70, Iss 4, Pp 895-899 (2023)
In our study we investigated the acute toxicity of а newly synthesized creatine lysinate as well as its effect on the biochemical parameters in mice. Creatine lysinate exerts better solubility in water (3.3%) in comparison to creatine monohydrate (1
Externí odkaz:
https://doaj.org/article/d7d55204531e4c66a1682606c8a87169
Autor:
Ivanka Kostadinova, Nikolai Danchev
Publikováno v:
Pharmacia, Vol 66, Iss 2, Pp 67-74 (2019)
In this review are described the preclinical and clinical pharmacological data as well as new therapeutic indications for the use of 4-aminopyridine. 4-aminopyridine is a potassium (K+) channel blocker that has a long history and various application
Externí odkaz:
https://doaj.org/article/af97cda93e514a85b96ab24a5ec07359
Publikováno v:
Bulletin of Experimental Biology and Medicine. 170:200-202
The effect of original peptide derivatives of galantamine on scopolamine-induced memory impairment in mice was assessed using the passive avoidance test over 12 days. It was found that some galantamine derivatives administered in a dose of 1/20LD50 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183497a810617a93c511ff2a95186f81
https://doi.org/10.1007/s10517-020-05032-z
https://doi.org/10.1007/s10517-020-05032-z
Autor:
Ivanka I. Kostadinova, Vessela Vitcheva, Irini Doytchinova, Irena Philipova, Nikolai Danchev, Georgi Stavrakov, Rumiana Simeonova, Iva Valkova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daaad42f6d2be85af1c2eaf90a244c54
https://doi.org/10.7546/crabs.2021.06.13
https://doi.org/10.7546/crabs.2021.06.13
Autor:
Irena Philipova, Ivanka I. Kostadinova, Vessela Vitcheva, Rumiana Simeonova, Irini Doytchinova, Nikolai Danchev, Georgi Stavrakov, Iva Valkova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8131e7090539054fc826aad1f984b1e
https://doi.org/10.7546/crabs.2021.02.08
https://doi.org/10.7546/crabs.2021.02.08
Autor:
Boycho Landzhov, Nikolai Danchev, Lyubomir T. Vezenkov, Ivanka I. Kostadinova, Lyubomir Marinov
Publikováno v:
Amino acids. 53(8)
The aim of this study was to assess the effect of newly synthesized derivatives of 4-aminopyridine (4-AP) on cuprizone-induced model of brain demyelination in mice. 4-AP is already approved for the treatment of walking difficulties in patients with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bef84c147a172b2c63b6d79530e178
https://pubmed.ncbi.nlm.nih.gov/34240251
https://pubmed.ncbi.nlm.nih.gov/34240251
Autor:
Ivanka I. Kostadinova, Rositsa Mihaylova, D. Tsekova, Lyubomir T. Vezenkov, Nikolay G. Vassilev, Nikolai Danchev
Publikováno v:
Current Alzheimer research. 16(3)
Background: Although no effective treatment for the Alzheimer’s disease currently exist, some drugs acting as Acetylcholinesterase inhibitors, like galanthamine have positively affected such patients. β- and/or γ-secretase inhibitors are another
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6af291b073d90c7701379b216e4d803
https://pubmed.ncbi.nlm.nih.gov/30819081
https://pubmed.ncbi.nlm.nih.gov/30819081
Autor:
Ivanka I. Kostadinova, Lyubomir T. Vezenkov, Borislav A. Anchev, Daniela S. Tsekova, Nikolay G. Vasilev, Kristian Fidanov, Nikolai Danchev
Publikováno v:
Proceedings of the 35th European Peptide Symposium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc0d1c0e18486f8f3e464c3f44336d68
https://doi.org/10.17952/35eps.2018.241
https://doi.org/10.17952/35eps.2018.241
Autor:
Lyubomir T. Vezenkov, Lilia Ilieva, Dancho L. Danalev, D. Nikolay Vassilev, Irina Nikolova, Anastasia Bakalova, Nikolai Danchev
Publikováno v:
Protein & Peptide Letters. 22:913-922
New derivatives of galanthamine containing peptide fragments with β-secretase inhibitor activity were synthesized. In position 6 of the galanthamine new shortened analogues of β-secretase inhibitor OM 99-2 (Boc-Val-Asn-Leu-Ala-OH and Boc-Val-Asn-Le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0004ed8d0768892b2efc06931458b8
https://doi.org/10.2174/0929866522666150701111642
https://doi.org/10.2174/0929866522666150701111642