Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Nikolai B, Gusev"'
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253432 (2021)
The small heat shock protein (sHsp) called HspB8 (formerly, Hsp22) is one of the least typical sHsp members, whose oligomerization status remains debatable. Here we analyze the effect of mutations in a highly conservative sequence located in the N-te
Externí odkaz:
https://doaj.org/article/8ca8b1bd332d4cd292859edb1713fd2b
Autor:
Ivan I. Dedov, Vsevolod A. Tkachuk, Nikolai B. Gusev, Vladimir P. Shirinsky, Aleksandr V. Vorotnikov, Tatiana N. Kochegura, Aleksander Y. Mayorov, Marina V. Shestakova
Publikováno v:
Сахарный диабет, Vol 21, Iss 5, Pp 364-375 (2018)
Type 2 diabetes mellitus (T2DM) is a socially important disease with only symptomatic therapy developed due to lack of knowledge about its pathogenesis and underlying mechanism. Insulin resistance (IR) is the first link of T2DM pathogenesis and resul
Externí odkaz:
https://doaj.org/article/5c1738b3a0bc4182853b0ade8b934222
Publikováno v:
Biochimie. 202:103-109
It is postulated that the small heat shock proteins directly interact with actin, affect formation and stabilize actin filaments. To verify this suggestion, we have analyzed interaction of recombinant human small heat shock protein HspB7 with skeleta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf71cd0229c9b8c00680ef74e1253554
https://doi.org/10.1016/j.biochi.2022.08.007
https://doi.org/10.1016/j.biochi.2022.08.007
Publikováno v:
Biochemistry (Moscow). 87:800-811
Small heat shock proteins (sHsps) play an important role in the maintenance of proteome stability and, particularly, in stabilization of the cytoskeleton and cell contractile apparatus. Cell exposure to different types of stress is accompanied by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e1dddc8890038d4013e3853e096d04
https://doi.org/10.1134/s0006297922080119
https://doi.org/10.1134/s0006297922080119
Autor:
Vladislav M. Shatov, Lydia K. Muranova, Maria A. Zamotina, Nikolai N. Sluchanko, Nikolai B. Gusev
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1085
The α-crystallin domain (ACD) is the hallmark of a diverse family of small heat shock proteins (sHsps). We investigated some of the ACD properties of five human sHsps as well as their interactions with different full-length sHsps. According to size-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec585c355165749a9bbf89a9d301a0f
Autor:
Vladislav M Shatov, Nikolai B. Gusev
Publikováno v:
Biochimie. 174:126-135
Physico-chemical properties of HspB6 S10F and P20L mutants with abrogated cardioprotective activity and associated with different forms of cardiomyopathy were analyzed. Under normal conditions both the wild-type HspB6 and its mutants formed small siz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82e1d743bb2a731a7623504d5ddbb2f
https://doi.org/10.1016/j.biochi.2020.04.021
https://doi.org/10.1016/j.biochi.2020.04.021
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126248 (2015)
Physico-chemical properties of the mutations G34R, P39L and E41K in the N-terminal domain of human heat shock protein B1 (HspB1), which have been associated with hereditary motor neuron neuropathy, were analyzed. Heat-induced aggregation of all mutan
Externí odkaz:
https://doaj.org/article/3d82948e80174eb6ae7880217a6320cf
Autor:
Maria V. Sudnitsyna, Nikolai B. Gusev
Publikováno v:
Cell Stress and Chaperones. 24:419-426
This study analyzed the interaction of commercial monoclonal anti-methylglyoxal antibodies that predominantly recognize argpyrimidine with unmodified and modified model proteins and small heat shock proteins. These antibodies specifically recognize m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c3404c09a133f64669c956a4c26194
https://doi.org/10.1007/s12192-019-00975-3
https://doi.org/10.1007/s12192-019-00975-3
Publikováno v:
Biochemistry. Biokhimiia. 86(Suppl 1)
HspB7 is one of ten human small heat shock proteins. This protein is expressed only in insulin-dependent tissues (heart, skeletal muscle, and fat tissue), and expression of HspB7 is regulated by many different factors. Single nucleotide polymorphism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854b20d63ea0421462d25b8145007091
https://pubmed.ncbi.nlm.nih.gov/33827396
https://pubmed.ncbi.nlm.nih.gov/33827396
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253432 (2021)
PLoS ONE
PLoS ONE
The small heat shock protein (sHsp) called HspB8 (formerly, Hsp22) is one of the least typical sHsp members, whose oligomerization status remains debatable. Here we analyze the effect of mutations in a highly conservative sequence located in the N-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f451fc86b09da974d41e3be394c3cfe
https://doaj.org/article/8ca8b1bd332d4cd292859edb1713fd2b
https://doaj.org/article/8ca8b1bd332d4cd292859edb1713fd2b